Skip to main content
Erschienen in: Journal of Gastrointestinal Cancer 2/2012

01.06.2012 | Brief Communication

Uterine Leiomyosarcoma Metastasis to the Pancreas: Report of a Case and Review of the Literature

verfasst von: Jaime Alonso Gómez, Álvaro Arjona Sánchez, David Martínez Cecilia, Rafael Díaz Nieto, Jorge Roldán de la Rúa, Amparo Valverde Martínez, Enrique Lizárraga Febres, Javier Padillo Ruiz, Sebastián Rufián Peña

Erschienen in: Journal of Gastrointestinal Cancer | Ausgabe 2/2012

Einloggen, um Zugang zu erhalten

Abstract

Introduction

Uterine leiomyosarcoma is an aggressive malignant tumor that often leads to metastatic dissemination, generally in the lungs, liver, brain, and bones. Despite the fact that pancreatic neoplasms spread easily, the pancreas is not a usual target organ from other neoplasms.

Case Report

We present a rare case of metastasis to the pancreas from uterine leiomyosarcoma treated with segmental resection with no recurrence at this stage. A review of the literature is later presented showing no similar case to what has been reported.

Discussion

Surgical resection of unique pancreatic metastases is a safe practice. An increase in the survival rate has been demonstrated after resection of metastases from renal cell carcinoma, although it has not been proved with metastases from other locations. Further trials are needed.
Literatur
1.
Zurück zum Zitat Leath 3rd CA, Huh WK, Straughn Jr JM, Conner MG. Uterine leiomyosarcoma metastatic to the thyroid. Obstet Gynecol. 2002;100(5 Pt 2):1122–4.PubMedCrossRef Leath 3rd CA, Huh WK, Straughn Jr JM, Conner MG. Uterine leiomyosarcoma metastatic to the thyroid. Obstet Gynecol. 2002;100(5 Pt 2):1122–4.PubMedCrossRef
2.
Zurück zum Zitat Ma L, Wu S, Zou Y, Li W, Gong L, Gerelle G, et al. One-stage surgery of low-grade malignant intravenous uterine leiomyosarcomatosis with right atrium extension. Ann Thorac Surg. 2007;84(2):644–7.PubMedCrossRef Ma L, Wu S, Zou Y, Li W, Gong L, Gerelle G, et al. One-stage surgery of low-grade malignant intravenous uterine leiomyosarcomatosis with right atrium extension. Ann Thorac Surg. 2007;84(2):644–7.PubMedCrossRef
3.
Zurück zum Zitat Moreno-Cabral RJ, Fukuyama O, Powell WS, Gold S, McNamara JJ. Surgical resection of giant metastatic leiomyosarcoma of the heart. J Thorac Cardiovasc Surg. 1987;94(3):447–9.PubMed Moreno-Cabral RJ, Fukuyama O, Powell WS, Gold S, McNamara JJ. Surgical resection of giant metastatic leiomyosarcoma of the heart. J Thorac Cardiovasc Surg. 1987;94(3):447–9.PubMed
4.
Zurück zum Zitat Saiz AD, Sachdev U, Brodman ML, Deligdisch L. Metastatic uterine leiomyosarcoma presenting as a primary sarcoma of the parotid gland. Obstet Gynecol. 1998;92(4 Pt 2):667–8.PubMedCrossRef Saiz AD, Sachdev U, Brodman ML, Deligdisch L. Metastatic uterine leiomyosarcoma presenting as a primary sarcoma of the parotid gland. Obstet Gynecol. 1998;92(4 Pt 2):667–8.PubMedCrossRef
5.
Zurück zum Zitat Kaziro GS. Metastatic uterine leiomyosarcoma to the tongue: report of case. J Oral Surg. 1981;39(2):128–9.PubMed Kaziro GS. Metastatic uterine leiomyosarcoma to the tongue: report of case. J Oral Surg. 1981;39(2):128–9.PubMed
6.
Zurück zum Zitat Aarvold A, Bann S, Giblin V, Wotherspoon A, Mudan SS. Osteosarcoma metastasising to the duodenum and pancreas. J Bone Joint Surg Br. 2007;89(4):542–4.PubMedCrossRef Aarvold A, Bann S, Giblin V, Wotherspoon A, Mudan SS. Osteosarcoma metastasising to the duodenum and pancreas. J Bone Joint Surg Br. 2007;89(4):542–4.PubMedCrossRef
7.
Zurück zum Zitat Eloubeidi MA, Jhala D, Chhieng DC, Jhala N, Eltoum I, Wilcox CM. Multiple late asymptomatic pancreatic metastases from renal cell carcinoma: diagnosis by endoscopic ultrasound-guided fine needle aspiration biopsy with immunocytochemical correlation. Dig Dis Sci. 2002;47(8):1839–42.PubMedCrossRef Eloubeidi MA, Jhala D, Chhieng DC, Jhala N, Eltoum I, Wilcox CM. Multiple late asymptomatic pancreatic metastases from renal cell carcinoma: diagnosis by endoscopic ultrasound-guided fine needle aspiration biopsy with immunocytochemical correlation. Dig Dis Sci. 2002;47(8):1839–42.PubMedCrossRef
8.
Zurück zum Zitat Noseda A, Gangji D, Cremer M. Acute pancreatitis as presenting symptom and sole manifestation of small cell lung carcinoma. Dig Dis Sci. 1987;32(3):327–31.PubMedCrossRef Noseda A, Gangji D, Cremer M. Acute pancreatitis as presenting symptom and sole manifestation of small cell lung carcinoma. Dig Dis Sci. 1987;32(3):327–31.PubMedCrossRef
9.
Zurück zum Zitat Yeung KY, Haidak DJ, Brown JA, Anderson D. Metastasis-induced acute pancreatitis in small cell bronchogenic carcinoma. Arch Intern Med. 1979;139(5):552–4.PubMedCrossRef Yeung KY, Haidak DJ, Brown JA, Anderson D. Metastasis-induced acute pancreatitis in small cell bronchogenic carcinoma. Arch Intern Med. 1979;139(5):552–4.PubMedCrossRef
10.
Zurück zum Zitat Niccolini DG, Graham JH, Banks PA. Tumor-induced acute pancreatitis. Gastroenterology. 1976;71(1):142–5.PubMed Niccolini DG, Graham JH, Banks PA. Tumor-induced acute pancreatitis. Gastroenterology. 1976;71(1):142–5.PubMed
11.
Zurück zum Zitat David AW, Samuel R, Eapen A, Vyas F, Joseph P, Sitaram V. Pancreatic metastasis from renal cell carcinoma years after nephrectomy: a case report and review of the literature. Trop Gastroenterol. 2006;27(4):175–6.PubMed David AW, Samuel R, Eapen A, Vyas F, Joseph P, Sitaram V. Pancreatic metastasis from renal cell carcinoma years after nephrectomy: a case report and review of the literature. Trop Gastroenterol. 2006;27(4):175–6.PubMed
12.
Zurück zum Zitat Sohn TA, Yeo CJ, Cameron JL, Nakeeb A, Lillemoe KD. Renal cell carcinoma metastatic to the pancreas: results of surgical management. J Gastrointest Surg. 2001;5(4):346–51.PubMedCrossRef Sohn TA, Yeo CJ, Cameron JL, Nakeeb A, Lillemoe KD. Renal cell carcinoma metastatic to the pancreas: results of surgical management. J Gastrointest Surg. 2001;5(4):346–51.PubMedCrossRef
13.
Zurück zum Zitat Reddy S, Edil BH, Cameron JL, Pawlik TM, Herman JM, Gilson MM, et al. Pancreatic resection of isolated metastases from nonpancreatic primary cancers. Ann Surg Oncol. 2008;15(11):3199–206.PubMedCrossRef Reddy S, Edil BH, Cameron JL, Pawlik TM, Herman JM, Gilson MM, et al. Pancreatic resection of isolated metastases from nonpancreatic primary cancers. Ann Surg Oncol. 2008;15(11):3199–206.PubMedCrossRef
14.
Zurück zum Zitat Sperti C, Pasquali C, Liessi G, Pinciroli L, Decet G, Pedrazzoli S. Pancreatic resection for metastatic tumors to the pancreas. J Surg Oncol. 2003;83(3):161–6.PubMedCrossRef Sperti C, Pasquali C, Liessi G, Pinciroli L, Decet G, Pedrazzoli S. Pancreatic resection for metastatic tumors to the pancreas. J Surg Oncol. 2003;83(3):161–6.PubMedCrossRef
15.
Zurück zum Zitat Stankard CE, Karl RC. The treatment of isolated pancreatic metastases from renal cell carcinoma: a surgical review. Am J Gastroenterol. 1992;87(11):1658–60.PubMed Stankard CE, Karl RC. The treatment of isolated pancreatic metastases from renal cell carcinoma: a surgical review. Am J Gastroenterol. 1992;87(11):1658–60.PubMed
16.
Zurück zum Zitat Bachmann J, Michalski CW, Bergmann F, Büchler MW, Kleeff J, Friess H. Metastasis of rectal adenocarcinoma to the pancreas. Two case reports and a review of the literature. JOP. 2007;8(2):214–22.PubMed Bachmann J, Michalski CW, Bergmann F, Büchler MW, Kleeff J, Friess H. Metastasis of rectal adenocarcinoma to the pancreas. Two case reports and a review of the literature. JOP. 2007;8(2):214–22.PubMed
17.
Zurück zum Zitat Hiotis SP, Klimstra DS, Conlon KC, Brennan MF. Results after pancreatic resection for metastatic lesions. Ann Surg Oncol. 2002;9:675–9.PubMedCrossRef Hiotis SP, Klimstra DS, Conlon KC, Brennan MF. Results after pancreatic resection for metastatic lesions. Ann Surg Oncol. 2002;9:675–9.PubMedCrossRef
18.
Zurück zum Zitat Z'graggen K, Fernandez-del Castillo C, Rattner DW, Sigala H, Warshaw AL. Metastases to the pancreas and their surgical extirpation. Arch Surg. 1998;133:413–7.PubMedCrossRef Z'graggen K, Fernandez-del Castillo C, Rattner DW, Sigala H, Warshaw AL. Metastases to the pancreas and their surgical extirpation. Arch Surg. 1998;133:413–7.PubMedCrossRef
19.
Zurück zum Zitat Birkmeyer JD, Siewers AE, Finlayson EV, Stukel TA, Lucas FL, Batista I, et al. Hospital volume and surgical mortality in the United States. N Engl J Med. 2002;346:1128–37.PubMedCrossRef Birkmeyer JD, Siewers AE, Finlayson EV, Stukel TA, Lucas FL, Batista I, et al. Hospital volume and surgical mortality in the United States. N Engl J Med. 2002;346:1128–37.PubMedCrossRef
20.
Zurück zum Zitat Büchler MW, Wagner M, Schmied BM, Uhl W, Friess H, Z’graggen K. Changes in morbidity after pancreatic resection: toward the end of completion pancreatectomy. Arch Surg. 2003;138:1310–4.PubMedCrossRef Büchler MW, Wagner M, Schmied BM, Uhl W, Friess H, Z’graggen K. Changes in morbidity after pancreatic resection: toward the end of completion pancreatectomy. Arch Surg. 2003;138:1310–4.PubMedCrossRef
21.
Zurück zum Zitat Wente MN, Kleeff J, Esposito I, Hartel M, Müller MW, Fröhlich BE, et al. Renal cancer cell metastasis into the pancreas: a single-center experience and overview of the literature. Pancreas. 2005;30:3.CrossRef Wente MN, Kleeff J, Esposito I, Hartel M, Müller MW, Fröhlich BE, et al. Renal cancer cell metastasis into the pancreas: a single-center experience and overview of the literature. Pancreas. 2005;30:3.CrossRef
Metadaten
Titel
Uterine Leiomyosarcoma Metastasis to the Pancreas: Report of a Case and Review of the Literature
verfasst von
Jaime Alonso Gómez
Álvaro Arjona Sánchez
David Martínez Cecilia
Rafael Díaz Nieto
Jorge Roldán de la Rúa
Amparo Valverde Martínez
Enrique Lizárraga Febres
Javier Padillo Ruiz
Sebastián Rufián Peña
Publikationsdatum
01.06.2012
Verlag
Springer US
Erschienen in
Journal of Gastrointestinal Cancer / Ausgabe 2/2012
Print ISSN: 1941-6628
Elektronische ISSN: 1941-6636
DOI
https://doi.org/10.1007/s12029-010-9172-x

Weitere Artikel der Ausgabe 2/2012

Journal of Gastrointestinal Cancer 2/2012 Zur Ausgabe

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.