nach oben

Erschienen in:

01.10.2020 | COVID-19 | Review Article Zur Zeit gratis

Cancer and Coronavirus Disease (COVID-19): Comorbidity, Mechanical Ventilation, and Death Risk

verfasst von: Mohammad Hossein Jarahzadeh, Fatemeh Asadian, Meraj Farbod, Bahare Meibodi, Hajar Abbasi, Mohammadali Jafari, Ali Raee-Ezzabadi, Reza Bahrami, Hossein Neamatzadeh

Erschienen in: Journal of Gastrointestinal Cancer | Ausgabe 1/2021

Einloggen, um Zugang zu erhalten

Abstract

Background

The presence of comorbidity poses a major clinical challenge in the care and treatment of COVID-19 patients. Moreover, having one or more comorbidities could be a life-threatening situation in COVID-19 patients. Cancer is substantially associated with significant morbidity and mortality in COVID-19 patients. However, there is not sufficient data to conclude that cancer patients have a higher risk of COVID-19 infection. In this study, we reviewed cancer comorbidity and risk of mechanical ventilation or death in patients with confirmed COVID-19.

Methods

A comprehensive systematic search was performed on PubMed, Scopus, Web of Science, SciELO, and CNKI, to find articles published until August 01, 2020. All relevant case series, case reports, systematic and narrative reviews, meta-analyses, and prospective and retrospective studies that reported clinical characteristics and epidemiological information of cancer patients infected with COVID-19 were included in the study.

Results

A total of 12 cohort studies exclusively on cancer patients with confirmed COVID-19 were selected.

Conclusions

According to the findings of this study, cancer was not among the most prevalent underlying diseases in patients with confirmed COVID-19. Moreover, cancer patients infected with COVID-19 had the lowest risk of mechanical ventilation or death than the non-cancer infected patients.

Karimi-Zarchi M, Neamatzadeh H, Dastgheib SA, Abbasi H, Mirjalili SR, Behforouz A, et al. Vertical transmission of coronavirus disease 19 (COVID-19) from infected pregnant mothers to neonates: a review. Fetal Pediatr Pathol. 2020;39:246–50.CrossRef

Schwartz DA, Graham AL. Potential maternal and infant outcomes from coronavirus 2019-nCoV (SARS-CoV-2) infecting pregnant women: lessons from SARS, MERS, and other human coronavirus infections. Viruses. 2020;12:194.CrossRef

Akbari H, Tabrizi R, Lankarani KB, Aria H, Vakili S, Asadian F, et al. The role of cytokine profile and lymphocyte subsets in the severity of coronavirus disease 2019 (COVID-19): a systematic review and meta-analysis. Life Sci. Elsevier Inc. 2020;258:118167.CrossRef

Nikpouraghdam M, Farahani AJ, Alishiri G, Heydari S, Ebrahimnia M, Samadinia H, et al. Epidemiological Characteristics of Coronavirus Disease 2019 (COVID-19) Patients in IRAN: A single Center Study. J Clin Virol. 2020;127:104378.CrossRef

Eslami H, Jalili M. The role of environmental factors to transmission of SARS-CoV-2 (COVID-19). AMB Express. 2020;10:92.CrossRef

Vardhana SA, Wolchok JD. The many faces of the anti-COVID immune response. J Exp Med. 2020;217:e20200678.CrossRef

Sanyaolu A, Okorie C, Marinkovic A, Patidar R, Younis K, Desai P, et al. Comorbidity and its impact on patients with COVID-19. SN Compr Clin Med. 2020;2:1069–76.CrossRef

Ejaz H, Alsrhani A, Zafar A, Javed H, Junaid K, Abdalla AE, et al. COVID-19 and comorbidities: Deleterious impact on infected patients. J Infect Public Health. 2020;S1876-0341:30594–3.

Xia Y, Jin R, Zhao J, Li W, Shen H. Risk of COVID-19 for patients with cancer. Lancet Oncol. 2020;21:e180.CrossRef

10.

Zhang Y, Li M, Gan L, Li B. Analysis of clinical characteristics of 5 tumor patients with coronavirus disease 2019. Guangdong Med J. 2020;41.

11.

Zhang L, Zhu F, Xie L, Wang C, Wang J, Chen R, et al. Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan, China. Ann Oncol. 2020;31:894–901.CrossRef

12.

Tian S, Hu W, Niu L, Liu H, Xu H, Xiao SY. Pulmonary pathology of early-phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer. J Thorac Oncol. 2020;15:700–4.CrossRef

13.

Moujaess E, Kourie HR, Ghosn M. Cancer patients and research during COVID-19 pandemic: a systematic review of current evidence. Crit Rev Oncol Hematol. 2020;150:102972.CrossRef

14.

Kuderer NM, Choueiri TK, Shah DP, Shyr Y, Rubinstein SM, Rivera DR, et al. Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study. Lancet. 2020;395:1907–18.CrossRef

15.

Singh AG, Deodhar J, Chaturvedi P. Navigating the impact of COVID-19 on palliative care for head and neck cancer. Head Neck. 2020;42:1144–6.CrossRef

16.

Kobayashi Y, Suh DH, Aoki D, Kim J-W. Management of ovarian cancer patients in affected areas during COVID-19 pandemic: Japan and Korea. J Gynecol Oncol. 2020;31:e65.CrossRef

17.

Rakhsha A, Azghandi S, Taghizadeh-Hesary F. COVID-19 pandemic and patients with cancer: the protocol of a Clinical Oncology center in Tehran, Iran. Rep Pract Oncol Radiother Urban Partn. 2020;25:765–7.CrossRef

18.

Burki TK. Cancer guidelines during the COVID-19 pandemic. Lancet Oncol. 2020;21:629–30.CrossRef

19.

Pooja S, Chaudhary P, Nayak LV, Rajender S, Saini KS, Deol D, et al. Polymorphic variations in IL-1β, IL-6 and IL-10 genes, their circulating serum levels and breast cancer risk in Indian women. Cytokine. 2012;60:122–8.CrossRef

20.

Tabrizi S, Trippa L, Cagney D, Tanguturi S, Ventz S, Fell G, et al. A Quantitative framework for modeling COVID-19 risk during adjuvant therapy using published randomized trials of glioblastoma in the elderly. Neuro-Oncology. 2020;22:918–27.CrossRef

21.

Polak SB, Van Gool IC, Cohen D, von der Thüsen JH, van Paassen J. A systematic review of pathological findings in COVID-19: a pathophysiological timeline and possible mechanisms of disease progression. Mod Pathol. 2020;1–11.

22.

Auld SC, Caridi-Scheible M, Blum JM, Robichaux C, Kraft C, Jacob JT, et al. ICU and ventilator mortality among critically ill adults with coronavirus disease 2019. Crit Care Med. 2020;10. https://doi.org/10.1097/CCM.0000000000004457.

23.

Nishiga M, Wang DW, Han Y, Lewis DB, Wu JC. COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives. Nature Reviews. Cardiol Nat Res. 2020;17:543–58.CrossRef

24.

Clark A, Jit M, Warren-Gash C, Guthrie B, Wang HHX, Mercer SW, et al. Global, regional, and national estimates of the population at increased risk of severe COVID-19 due to underlying health conditions in 2020: a modelling study. Lancet Glob Health. 2020;8:e1003–17.CrossRef

25.

Kermali M, Khalsa RK, Pillai K, Ismail Z, Harky A. The role of biomarkers in diagnosis of COVID-19 – a systematic review. Life Sci. Elsevier Inc. 2020;254:117788.CrossRef

26.

Williamson EJ, Walker AJ, Bhaskaran K, Bacon S, Bates C, Morton CE, et al. Factors associated with COVID-19-related death using OpenSAFELY. Nature. Nat Res. 2020;584:430–6.

27.

Albano D, Bertagna F, Bertolia M, Bosio G, Lucchini S, Motta F, et al. Incidental findings suggestive of COVID-19 in asymptomatic patients undergoing nuclear medicine procedures in a high prevalence region. J Nucl Med. 2020;61:632–6.CrossRef

28.

Curigliano G, Cardoso MJ, Poortmans P, Gentilini O, Pravettoni G, Mazzocco K, et al. Recommendations for triage, prioritization and treatment of breast cancer patients during the COVID-19 pandemic. Breast. 2020;52:8–16.CrossRef

29.

Wang W, Tang J, Wei F. Updated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan, China. J Med Virol. 2020;92:441–7.CrossRef

30.

Guan W, Liang W, Zhao Y, Liang H, Chen Z, Li Y, et al. Comorbidity and its impact on 1590 patients with Covid-19 in China: a nationwide analysis. Eur Respir J. 2020;55:2000547.CrossRef

31.

Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, et al. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area. JAMA. 2020;323:2052–9.CrossRef

32.

Desai A, Sachdeva S, Parekh T, Desai R. COVID-19 and cancer: lessons from a pooled meta-analysis. JCO Glob Oncol. 2020;6:557–9.CrossRef

33.

Shovlin CL, Vizcaychipi MP. Implications for COVID-19 triage from the ICNARC report of 2204 COVID-19 cases managed in UK adult intensive care units. Emerg Med J. 2020;37:332–3.CrossRef

34.

Zhang H, Huang Y, Xie C. The treatment and outcome of a lung cancer patient infected with SARS-CoV-2. J Thorac Oncol. 2020;15:e63–4.CrossRef

35.

Leonetti A, Facchinetti F, Zielli T, Brianti E, Tiseo M. COVID-19 in lung cancer patients receiving ALK/ROS1 inhibitors. Eur J Cancer. 2020;132:122–4.CrossRef

36.

De Felice F, Polimeni A, Valentini V. The impact of Coronavirus (COVID-19) on head and neck cancer patients’ care. Radiother Oncol. 2020;147:84–5.CrossRef

37.

Salari A, Shirkhoda M. COVID-19 pandemic & head and neck cancer patients management: the role of virtual multidisciplinary team meetings. Oral Oncol. 2020;105:104693.CrossRef

38.

Yan F, Nguyen SA. Head and neck cancer: a high-risk population for COVID-19. Head Neck. 2020;42:1150–2.CrossRef

39.

Liang W, Guan W, Chen R, Wang W, Li J, Xu K, et al. Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China. Lancet Oncol. 2020;21:335–7.CrossRef

Titel: Cancer and Coronavirus Disease (COVID-19): Comorbidity, Mechanical Ventilation, and Death Risk
verfasst von: Mohammad Hossein Jarahzadeh
Fatemeh Asadian
Meraj Farbod
Bahare Meibodi
Hajar Abbasi
Mohammadali Jafari
Ali Raee-Ezzabadi
Reza Bahrami
Hossein Neamatzadeh
Publikationsdatum: 01.10.2020
Verlag: Springer US
Schlagwort: COVID-19
Erschienen in: Journal of Gastrointestinal Cancer / Ausgabe 1/2021
Print ISSN: 1941-6628
Elektronische ISSN: 1941-6636
DOI: https://doi.org/10.1007/s12029-020-00529-2

Springer Medizin

Cancer and Coronavirus Disease (COVID-19): Comorbidity, Mechanical Ventilation, and Death Risk