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01.04.2020 | AdisInsight Report

Remimazolam: First Approval

verfasst von: Susan J. Keam

Erschienen in: Drugs | Ausgabe 6/2020

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Abstract

Remimazolam (Anerem^® in Japan; ByFavo™ in the USA; Aptimyda™ in the EU) is an ultra-short-acting intravenous (IV) benzodiazepine sedative/anesthetic being developed by PAION AG in conjunction with a number of commercial partners for use in anesthesia and procedural sedation. Remimazolam was approved on 23 January 2020 in Japan for use in general anesthesia in adult patients. Remimazolam is also undergoing regulatory assessment in South Korea for this indication and for use in procedural sedation in the USA, the EU and China. This article summarises the major milestones in the development of remimazolam for this first approval for the induction and maintenance of general anaesthesia, and its potential upcoming approvals in general anaesthesia and procedural sedation.

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12.

PAION AG. PAION grants Cosmo Pharmaceuticals remimazolam license in the U.S. and Cosmo becomes largest shareholder of PAION AG [media release]. 24 June 2016. https://www.paion.com.

13.

PAION AG. PAION grants remimazolam license for Southeast Asia to Hana Pharm [media release]. 8 Jan 2020. https://www.paion.com.

14.

PAION AG. PAION announces clinical development progress with remimazolam by its partner Hana Pharm in South Korea [media release]. 22 Mar 2018. https://www.paion.com/.

15.

PAION AG. Paion grants exclusive license to Mundipharma for development and commercialization of remimazolam in Japan [media release]. 18 Dec 2017. https://www.paion.com.

16.

PAION AG. PAION grants licence to remimazolam in Canada to Pendopharm [media release]. 9 July 2015. https://www.paion.com/.

17.

PAION AG. PAION AG grants license to R-Pharm for remimazolam [media release]. 30 Oct 2013. https://www.paion.com.

18.

PAION AG. PAION AG grants license for Turkey to add to R-Pharm territory [media release]. 26 Nov 2013. https://www.paion.com/.

19.

TRPharm. PAION AG (ISIN DE000A0B65S3; Frankfurt Stock Exchange Prime Standard: PA8), a specialty pharma company, and R-Pharm, Russia, today announced that they have extended their license agreements for remimazolam to include the "MENA Region" (Middle East andNorth Africa) [media release]. 17 June 2014. https://www.trpharm.com.

20.

PAION AG. PAION AG grants license to Yichang Humanwell for remimazolam in China [media release]. 18 July 2012. https://www.paion.com/.

21.

CeNeS Pharmaceuticals plc. CeNeS licenses new intravenous anaesthetic to Ono in Japan [media release]. 6 Aug 2007. https://www.cenes.com.

22.

PAION AG. PAION's partner Ono decides not to file for regulatory approval of remimazolam in Japan and will return its remimazolam rights for Japan to Paion [media release]. 5 Nov 2014. https://www.paion.de.

23.

PAION AG. PAION AG reports on financial year and financial results 2015 [media release]. 22 Mar 2016. https://www.paion.de.

24.

PAION AG. PAION AG completes acquisition of CeNeS [media release]. 23 June 2008. https://www.paion.de.

25.

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26.

Ono Pharmaceutical Co L. Ono enters into license agreement with CeNeS Limited [media release]. 6 Aug 2007. https://www.cenes.com.

27.

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28.

PAION AG. European Patent Office grants formulation patent for remimazolam in the EU [media release]. 28 Sep 2017. https://www.paion.com.

29.

PAION AG. US Patent & Trademark office grants substance patent for remimazolam besylate [media release]. 12 Feb 2016. https://www.paion.com/.

30.

PAION AG. Japan Patent Office grants dosing patent for remimazolam in Japan [media release]. 13 Oct 2017. https://www.paion.com/.

31.

CeNeS Pharmaceuticals plc. CeNeS is granted patent for short-acting sedatives, including CNS 7056X, by the European Patent Office [media release]. 8 Feb 2006. https://www.cenes.com.

32.

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33.

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35.

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39.

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40.

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44.

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45.

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46.

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49.

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51.

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Titel: Remimazolam: First Approval
verfasst von: Susan J. Keam
Publikationsdatum: 01.04.2020
Verlag: Springer International Publishing
Erschienen in: Drugs / Ausgabe 6/2020
Print ISSN: 0012-6667
Elektronische ISSN: 1179-1950
DOI: https://doi.org/10.1007/s40265-020-01299-8

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Remimazolam: First Approval

Abstract

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Abstract

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