Introduction
Materials & methods
Study design, participants and data source
Definitions and data collection
Statistical analysis
Results
Patient features and vitamin D status
Total N (%) | 25(OH) D level ≥ 30 ng/mL N (%) | 25(OH) D level ≤ 30 ng/mL N (%) | P- value | |
---|---|---|---|---|
Socio-demographic characteristics | ||||
Gender | ||||
Female | 66 (43.13) | 23 (40.35) | 43 (44.79) | 0.601 |
Male | 87 (53.86) | 34 (59.64) | 53 (55.2) | |
Age group (years old) | ||||
50> | 55 (35.9) | 13 (22.8) | 42 (43.75) | 0.020 |
50–65 | 54 (35.3) | 22 (38.59) | 32 (33.33) | |
> 65 | 44 (28.8) | 22 (38.59) | 22 (22.91) | |
Body mass index (BMI) | 29.909 ± 5.81 | 29.15 ± 5.71 | 29.92 ± 5.92 | 0.321 |
Living area | ||||
Rural | 57 (37.25) | 20 (35.08) | 37 (38.54) | 0.732 |
Urban | 96 (62.7) | 37 (64.91) | 59 (61.45) | |
Preexisting comorbidities | ||||
Diabetes | 41 (26.79) | 19 (38.59) | 22 (22.91) | 0.183 |
Hypertension | 44 (28.75) | 26 (45.61) | 18 (18.75) | 0.001 |
Cardiovascular disease | 30 (19.6) | 17 (29.82) | 13 (13.54) | 0.022 |
Dyslipidemia | 10 (6.53) | 1 (1.75) | 9 (9.37) | 0.091 |
Hypothyroidism | 9 (5.88) | 0 | 9 (9.37) | 0.023 |
Asthma | 6 (3.92) | 0 | 6 (6.25) | 0.081 |
Malignancy | 3 (1.96) | 2 | 1 (1.04) | 0.550 |
Chronic liver disease | 2 (1.3) | 1 (1.75) | 1 (1.04) | 1 |
Chronic Kidney Disease | 1 (0.65) | 1 (1.75) | 0 | 0.371 |
Outcomes of patients | Total N (%) | 25(OH) D level ≥ 30 N (%) | 25(OH) D level ≤ 30 N (%) | P- value |
---|---|---|---|---|
Bilateral lung involvement | 28 (17.64) | 10 (17.54) | 18 (17.7) | 0.302 |
ICU admission | 10 (6.53) | 3 (5.26) | 7 (7.29) | 0.512 |
Invasive mechanical ventilator use | 3 (1.96) | 1 (1.75) | 2 (2.083) | 1 |
Non-invasive ventilation | 15 (9.08) | 5 (8.77) | 10 (10.41) | 1 |
Mild form of COVID-19 | 72 (41.7) | 24 (42.1) | 48 (50) | 0.093 |
Moderate form of COVID-19 | 63 (41.2) | 24 (42.1) | 39 (40.62) | |
Severe form of COVID-19 | 18 (11.8) | 9 (15.78) | 9 (9.37) | |
Death | 5 (3.26) | 2 (3.57) | 3 (3.12) | 1 |
Duration of hospitalization (days): Mean ± SD | 6.3 ± 4.12 | 6.36 ± 4.35 | 6.25 ± 4.01 | 0.801 |
Ordinal logistic regression analyses for severity of COVID-19
Univariate and multivariable regression analysis for adverse outcome of COVID-19
Univariate Regression | Multivariable Regression | |||
---|---|---|---|---|
Outcome | Duration of hospitalization (days) | Duration of hospitalization (days) | ||
Variables | ||||
Betaa | P-value | Betaa | P-value | |
Vitamin D level | 0.01 | 0.876 | −0.05 | 0.543 |
Gender | 0.08 | 0.309 | NA | NA |
Body mass index (BMI) | −0.01 | 0.889 | NA | NA |
Living Area | −0.08 | 0.336 | NA | NA |
Diabetes | 0.05 | 0.518 | NA | NA |
Hypertension | 0.10 | 0.199 | 0.09 | 0.300 |
Cardiovascular disease | 0.02 | 0.769 | NA | NA |
Dyslipidemia | −0.12 | 0.133 | − 0.11 | 0.162 |
Hypothyroidism | −0.13 | 0.120 | −0.12 | 0.159 |
Asthma | − 0.08 | 0.277 | NA | NA |
Malignancy | −0.03 | 0.683 | NA | NA |
Chronic liver disease | −0.02 | 0.784 | NA | NA |
Chronic Kidney Disease | −0.01 | 0.942 | NA | NA |