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01.08.2010 | Review

Bench-to-bedside review: Molecular pharmacology and clinical use of inert gases in anesthesia and neuroprotection

verfasst von: Robert Dickinson, Nicholas P Franks

Erschienen in: Critical Care | Ausgabe 4/2010

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Abstract

In the past decade there has been a resurgence of interest in the clinical use of inert gases. In the present paper we review the use of inert gases as anesthetics and neuroprotectants, with particular attention to the clinical use of xenon. We discuss recent advances in understanding the molecular pharmacology of xenon and we highlight specific pharmacological targets that may mediate its actions as an anesthetic and neuroprotectant. We summarize recent in vitro and in vivo studies on the actions of helium and the other inert gases, and discuss their potential to be used as neuroprotective agents.

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Titel: Bench-to-bedside review: Molecular pharmacology and clinical use of inert gases in anesthesia and neuroprotection
verfasst von: Robert Dickinson
Nicholas P Franks
Publikationsdatum: 01.08.2010
Verlag: BioMed Central
Erschienen in: Critical Care / Ausgabe 4/2010
Elektronische ISSN: 1364-8535
DOI: https://doi.org/10.1186/cc9051

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Bench-to-bedside review: Molecular pharmacology and clinical use of inert gases in anesthesia and neuroprotection

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