Fig. 5
Effect of miR-338-3p overexpression on migration, invasion, and the expression of Vimentin and E-cadherin of osteosarcoma cells. Following transfection with NC and miR-338-3p mimics, transwell assay was performed to measure the migratory (A) and invasive (B) capacities of MG-63 and Saos2 cells. Left image shows representative results for migration or invasion of cells from each treatment group. Right image shows the average number of migratory or invasive cells per field among different treatment groups. Data are expressed as mean ± SD, *P < 0.05. Western blot was carried out to detect the expression of Vimentin and E-cadherin (C)