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01.10.2013 | Case study

Locally advanced verrucous carcinoma of the oral cavity

Treatment using customized mold HDR brachytherapy instead of hemi-maxillectomy

verfasst von: K.M.J. van Gestel, D.J.M. Buurman, R. Pijls, P.A.W.H. Kessler, P.L.A. van den Ende, A.L. Hoffmann, E.G.C. Troost, MD PhD

Erschienen in: Strahlentherapie und Onkologie | Ausgabe 10/2013

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Abstract

Background

Oral verrucous carcinomas are locally invasive but rarely metastasize. Current treatment options include surgery and external beam radiotherapy (EBRT). In medical inoperable patients or irresectable tumors, high-dose-rate (HDR) brachytherapy is a valid alternative.

Case

We present an 85-year-old man with functionally irresectable cT3N0M0 verrucous carcinoma superficially spreading along the upper alveolar ridge to the retro-alveolar triangle, with infiltration of the left soft and hard palate and buccal mucosa. Using a customized intraoral mold, this patient was treated with HDR brachytherapy delivering a dose of 48 Gy in 12 fractions three times per week. Treatment was well tolerated, and after prolonged confluent mucositis the tumor is in complete remission.

Review of literature and conclusion

The scarce literature on customized mold HDR brachytherapy in maxillary tumors is reviewed and recommendations for other head and neck tumors are given.

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Titel: Locally advanced verrucous carcinoma of the oral cavity
Treatment using customized mold HDR brachytherapy instead of hemi-maxillectomy
verfasst von: K.M.J. van Gestel
D.J.M. Buurman
R. Pijls
P.A.W.H. Kessler
P.L.A. van den Ende
A.L. Hoffmann
E.G.C. Troost, MD PhD
Publikationsdatum: 01.10.2013
Verlag: Springer Berlin Heidelberg
Erschienen in: Strahlentherapie und Onkologie / Ausgabe 10/2013
Print ISSN: 0179-7158
Elektronische ISSN: 1439-099X
DOI: https://doi.org/10.1007/s00066-013-0412-4

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Neu im Fachgebiet Onkologie

Adjuvante Immuntherapie verlängert Leben bei RCC

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

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