Skip to main content
Erschienen in: Archives of Orthopaedic and Trauma Surgery 5/2014

01.05.2014 | Orthopaedic Surgery

Lumbar spine stability after combined application of interspinous fastener and modified posterior lumbar interbody fusion: a biomechanical study

verfasst von: Xiuchun Yu, Lei Zhu, Qing Su

Erschienen in: Archives of Orthopaedic and Trauma Surgery | Ausgabe 5/2014

Einloggen, um Zugang zu erhalten

Abstract

Introduction

Posterior lumbar interbody fusion (PLIF) and internal fixation are commonly performed for the treatment of lower back pain due to lumbar spinal degeneration. We have developed a novel interspinous fixation device, the interspinous fastener (ISF) for potential use in the surgical management of degenerative spinal disease. The aim of this study was to assess the in vitro biomechanical characteristics of calf lumbar spine specimens after ISF fixation with modified PLIF.

Materials and methods

Ten lumbar spine (L3–L6) specimens from ten fresh calf cadavers (8–10 weeks of age) were used. Each specimen underwent sequential testing for each of the following four groups: no instrumentation (INTACT); interspinous fusion device fixation + PLIF (ISF); unilateral pedicle screw and titanium rod fixation + PLIF (UPS); bilateral pedicle screw and titanium rod fixation + PLIF (BPS). Outcome measures included angular range of motion (ROM) during unloaded and loaded (8 Nm) flexion, extension, left bending, right bending, left torsion and right torsion.

Results

For all unloaded and loaded assessments, ROM was significantly higher in the INTACT group compared with all other groups (P < 0.05). Similarly, ROM was significantly higher in the UPS group (indicating decreased stability) compared with the ISF and BPS groups (P < 0.05). The only significant difference between the ISF and BPS groups was in the ROM with unloaded extension (higher in the BPS group, P = 0.006).

Conclusions

We found that ISF fixation with PLIF of the lower lumbar spine provided biomechanical stability that was equivalent to that associated with bilateral pedicle screw/rod fixation with PLIF. The ISF shows potential as an alternative means of fixation in the surgical management of degenerative spinal disease.
Literatur
2.
Zurück zum Zitat Freemont AJ (2009) The cellular pathobiology of the degenerate intervertebral disc and discogenic back pain. Rheumatology (Oxford) 48:5–10CrossRef Freemont AJ (2009) The cellular pathobiology of the degenerate intervertebral disc and discogenic back pain. Rheumatology (Oxford) 48:5–10CrossRef
3.
Zurück zum Zitat Hughes SP, Freemont AJ, Hukins DW, McGregor AH, Roberts S (2012) The pathogenesis of degeneration of the intervertebral disc and emerging therapies in the management of back pain. J Bone Joint Surg Br 94:1298–1304PubMedCrossRef Hughes SP, Freemont AJ, Hukins DW, McGregor AH, Roberts S (2012) The pathogenesis of degeneration of the intervertebral disc and emerging therapies in the management of back pain. J Bone Joint Surg Br 94:1298–1304PubMedCrossRef
5.
Zurück zum Zitat Spoor AB, Oner FC (2013) Minimally invasive spine surgery in chronic low back pain patients. J Neurosurg Sci 57:203–218PubMed Spoor AB, Oner FC (2013) Minimally invasive spine surgery in chronic low back pain patients. J Neurosurg Sci 57:203–218PubMed
6.
Zurück zum Zitat Atlas SJ, Nardin RA (2003) Evaluation and treatment of low back pain: an evidence-based approach to clinical care. Muscle Nerve 27:265–284PubMedCrossRef Atlas SJ, Nardin RA (2003) Evaluation and treatment of low back pain: an evidence-based approach to clinical care. Muscle Nerve 27:265–284PubMedCrossRef
7.
Zurück zum Zitat Mummaneni PV, Haid RW, Rodts GE (2004) Lumbar interbody fusion: state-of-the-art technical advances. Invited submission from the Joint Section Meeting on Disorders of the Spine and Peripheral Nerves, March 2004. J Neurosurg Spine 1:24–30PubMedCrossRef Mummaneni PV, Haid RW, Rodts GE (2004) Lumbar interbody fusion: state-of-the-art technical advances. Invited submission from the Joint Section Meeting on Disorders of the Spine and Peripheral Nerves, March 2004. J Neurosurg Spine 1:24–30PubMedCrossRef
8.
Zurück zum Zitat Yu AK, Siegfried CM, Chew B, Hobbs J, Sabersky A, Jho DJ, Cook DJ, Bellotte JB, Whiting DM, Cheng BC (2012) Biomechanics of posterior dynamic fusion systems in the lumbar spine: implications for stabilization with improved arthrodesis. J Spinal Disord Tech Yu AK, Siegfried CM, Chew B, Hobbs J, Sabersky A, Jho DJ, Cook DJ, Bellotte JB, Whiting DM, Cheng BC (2012) Biomechanics of posterior dynamic fusion systems in the lumbar spine: implications for stabilization with improved arthrodesis. J Spinal Disord Tech
9.
Zurück zum Zitat Esses SI, Sachs BL, Dreyzin V (1993) Complications associated with the technique of pedicle screw fixation. A selected survey of ABS members. Spine (Phila Pa 1976) 18:2231–2238 (discussion 8–9)CrossRef Esses SI, Sachs BL, Dreyzin V (1993) Complications associated with the technique of pedicle screw fixation. A selected survey of ABS members. Spine (Phila Pa 1976) 18:2231–2238 (discussion 8–9)CrossRef
11.
Zurück zum Zitat Wang JC, Haid RW Jr, Miller JS, Robinson JC (2006) Comparison of CD HORIZON SPIRE spinous process plate stabilization and pedicle screw fixation after anterior lumbar interbody fusion. Invited submission from the Joint Section Meeting on Disorders of the Spine and Peripheral Nerves, March 2005. J Neurosurg Spine 4:132–136PubMedCrossRef Wang JC, Haid RW Jr, Miller JS, Robinson JC (2006) Comparison of CD HORIZON SPIRE spinous process plate stabilization and pedicle screw fixation after anterior lumbar interbody fusion. Invited submission from the Joint Section Meeting on Disorders of the Spine and Peripheral Nerves, March 2005. J Neurosurg Spine 4:132–136PubMedCrossRef
12.
Zurück zum Zitat Gillespie KA, Dickey JP (2004) Biomechanical role of lumbar spine ligaments in flexion and extension: determination using a parallel linkage robot and a porcine model. Spine (Phila Pa 1976) 29:1208–1216CrossRef Gillespie KA, Dickey JP (2004) Biomechanical role of lumbar spine ligaments in flexion and extension: determination using a parallel linkage robot and a porcine model. Spine (Phila Pa 1976) 29:1208–1216CrossRef
13.
Zurück zum Zitat Ma XY, Yin QS, Wu ZH, Xia H, Liu JF, Xiang M, Zhao WD, Zhong SZ (2009) C1 pedicle screws versus C1 lateral mass screws: comparisons of pullout strengths and biomechanical stabilities. Spine 34:371–377PubMedCrossRef Ma XY, Yin QS, Wu ZH, Xia H, Liu JF, Xiang M, Zhao WD, Zhong SZ (2009) C1 pedicle screws versus C1 lateral mass screws: comparisons of pullout strengths and biomechanical stabilities. Spine 34:371–377PubMedCrossRef
14.
Zurück zum Zitat Zhang J, He X, Li H, Wang D, Zhao W, Xu J, Lan B, Xu S (2006) Biomechanical study of anterior cervical corpectomy and step-cut grafting with bioabsorbable screws fixation in cadaveric cervical spine model. Spine (Phila Pa 1976) 31:2195–2201CrossRef Zhang J, He X, Li H, Wang D, Zhao W, Xu J, Lan B, Xu S (2006) Biomechanical study of anterior cervical corpectomy and step-cut grafting with bioabsorbable screws fixation in cadaveric cervical spine model. Spine (Phila Pa 1976) 31:2195–2201CrossRef
15.
Zurück zum Zitat Pradhan BB, Turner AW, Zatushevsky MA, Cornwall GB, Rajaee SS, Bae HW (2012) Biomechanical analysis in a human cadaveric model of spinous process fixation with an interlaminar allograft spacer for lumbar spinal stenosis. Laboratory investigation. J Neurosurg Spine 16:585–593PubMedCrossRef Pradhan BB, Turner AW, Zatushevsky MA, Cornwall GB, Rajaee SS, Bae HW (2012) Biomechanical analysis in a human cadaveric model of spinous process fixation with an interlaminar allograft spacer for lumbar spinal stenosis. Laboratory investigation. J Neurosurg Spine 16:585–593PubMedCrossRef
16.
Zurück zum Zitat Kettler A, Drumm J, Heuer F, Haeussler K, Mack C, Claes L, Wilke HJ (2008) Can a modified interspinous spacer prevent instability in axial rotation and lateral bending? A biomechanical in vitro study resulting in a new idea. Clin Biomech (Bristol, Avon) 23:242–247CrossRef Kettler A, Drumm J, Heuer F, Haeussler K, Mack C, Claes L, Wilke HJ (2008) Can a modified interspinous spacer prevent instability in axial rotation and lateral bending? A biomechanical in vitro study resulting in a new idea. Clin Biomech (Bristol, Avon) 23:242–247CrossRef
17.
Zurück zum Zitat Cripton PA, Bruehlmann SB, Orr TE, Oxland TR, Nolte LP (2000) In vitro axial preload application during spine flexibility testing: towards reduced apparatus-related artefacts. J Biomech 33:1559–1568PubMedCrossRef Cripton PA, Bruehlmann SB, Orr TE, Oxland TR, Nolte LP (2000) In vitro axial preload application during spine flexibility testing: towards reduced apparatus-related artefacts. J Biomech 33:1559–1568PubMedCrossRef
18.
Zurück zum Zitat Fan J, Yu GR, Liu F, Zhao J, Zhao WD (2010) A biomechanical study on the direct repair of spondylolysis by different techniques of fixation. Orthop Surg 2:46–51PubMedCrossRef Fan J, Yu GR, Liu F, Zhao J, Zhao WD (2010) A biomechanical study on the direct repair of spondylolysis by different techniques of fixation. Orthop Surg 2:46–51PubMedCrossRef
19.
Zurück zum Zitat Karahalios DG, Kaibara T, Porter RW, Kakarla UK, Reyes PM, Baaj AA, Yaqoobi AS, Crawford NR (2010) Biomechanics of a lumbar interspinous anchor with anterior lumbar interbody fusion. Neurosurg Spine 12:372–380CrossRef Karahalios DG, Kaibara T, Porter RW, Kakarla UK, Reyes PM, Baaj AA, Yaqoobi AS, Crawford NR (2010) Biomechanics of a lumbar interspinous anchor with anterior lumbar interbody fusion. Neurosurg Spine 12:372–380CrossRef
20.
Zurück zum Zitat Zhu L, Yu XC, Lu CL (2013) A study on the biomechanical stability offered by interspinous fastener combined with interbody fusion for lower lumbar spine through three-dimensional finite element analysis. Orthop Biomech Mat Clin Study 10:55–60 (in Chinese) Zhu L, Yu XC, Lu CL (2013) A study on the biomechanical stability offered by interspinous fastener combined with interbody fusion for lower lumbar spine through three-dimensional finite element analysis. Orthop Biomech Mat Clin Study 10:55–60 (in Chinese)
21.
Zurück zum Zitat McAfee PC (1999) Interbody fusion cages in reconstructive operations on the spine. J Bone Joint Surg Am 81:859–880PubMed McAfee PC (1999) Interbody fusion cages in reconstructive operations on the spine. J Bone Joint Surg Am 81:859–880PubMed
22.
Zurück zum Zitat Teo EC, Lee KK, Qiu TX, Ng HW, Yang K (2004) The biomechanics of lumbar graded facetectomy under anterior-shear load. IEEE Trans Biomed Eng 51:443–449PubMedCrossRef Teo EC, Lee KK, Qiu TX, Ng HW, Yang K (2004) The biomechanics of lumbar graded facetectomy under anterior-shear load. IEEE Trans Biomed Eng 51:443–449PubMedCrossRef
23.
Zurück zum Zitat Kettler A, Liakos L, Haegele B, Wilke HJ (2007) Are the spines of calf, pig and sheep suitable models for pre-clinical implant tests? Eur Spine J 16:2186–2192PubMedCentralPubMedCrossRef Kettler A, Liakos L, Haegele B, Wilke HJ (2007) Are the spines of calf, pig and sheep suitable models for pre-clinical implant tests? Eur Spine J 16:2186–2192PubMedCentralPubMedCrossRef
Metadaten
Titel
Lumbar spine stability after combined application of interspinous fastener and modified posterior lumbar interbody fusion: a biomechanical study
verfasst von
Xiuchun Yu
Lei Zhu
Qing Su
Publikationsdatum
01.05.2014
Verlag
Springer Berlin Heidelberg
Erschienen in
Archives of Orthopaedic and Trauma Surgery / Ausgabe 5/2014
Print ISSN: 0936-8051
Elektronische ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-014-1977-9

Weitere Artikel der Ausgabe 5/2014

Archives of Orthopaedic and Trauma Surgery 5/2014 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Mehr Frauen im OP – weniger postoperative Komplikationen

21.05.2024 Allgemeine Chirurgie Nachrichten

Ein Frauenanteil von mindestens einem Drittel im ärztlichen Op.-Team war in einer großen retrospektiven Studie aus Kanada mit einer signifikanten Reduktion der postoperativen Morbidität assoziiert.

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

Klinikreform soll zehntausende Menschenleben retten

15.05.2024 Klinik aktuell Nachrichten

Gesundheitsminister Lauterbach hat die vom Bundeskabinett beschlossene Klinikreform verteidigt. Kritik an den Plänen kommt vom Marburger Bund. Und in den Ländern wird über den Gang zum Vermittlungsausschuss spekuliert.

TEP mit Roboterhilfe führt nicht zu größerer Zufriedenheit

15.05.2024 Knie-TEP Nachrichten

Der Einsatz von Operationsrobotern für den Einbau von Totalendoprothesen des Kniegelenks hat die Präzision der Eingriffe erhöht. Für die postoperative Zufriedenheit der Patienten scheint das aber unerheblich zu sein, wie eine Studie zeigt.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.