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Erschienen in: World Journal of Surgery 10/2017

26.05.2017 | Original Scientific Report

Lymph Node Retrieval is Inferior in the Modified Merendino Resection for Early Barrett’s Carcinoma: A Matched-Pair Comparison with Ivor Lewis Resection

verfasst von: Thomas Haist, Markus Mann, Christina Oetzmann von Sochaczewski, Michael Pauthner, Annette Fisseler-Eckhoff, Dietmar Lorenz

Erschienen in: World Journal of Surgery | Ausgabe 10/2017

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Abstract

Aim of the study

A matched-pair comparison between the modified Merendino resection (MER) and Ivor Lewis resection (ILR) for early Barrett’s carcinoma.

Background

Early adenocarcinoma of the esophagus (eACE) with positive risk factors for lymph node metastasis (LNM) needs surgery for cure. MER appeared to be an alternative to ILR.

Methods

Between July 2000 and July 2012, 156 patients with high-grade dysplasia or eACE received ILR, whereas in 30 cases MER was performed in a tertiary care center for GI Surgery. A matched-pair analysis was performed on the basis of sex, age, BMI, ASA classification and tumor stage. Thirty patients were assigned to each group. The data were analyzed regarding perioperative aspects (e.g., operating time, hospital stay, complications, number of lymph nodes) and survival analysis.

Results

The mean operating time was 301.7 min for ILR, compared to 255.4 min for MER (p = 0.044). The hospital stay following ILR was significantly longer than for MER (22.4 days ILR vs. 16.4 days MER, p = 0.023). There was no statistically significant difference regarding complications between the two groups (p = 0.463). The number of resected lymph nodes was significantly lower in the MER group (median 21) compared to the ILR group, where a median of 31 lymph nodes could be removed (p < 0.001). There was no statistically significant difference in overall (p = 0.145) or tumor-specific survival (p = 0.353).

Conclusions

Lymph node retrieval is significantly inferior in the MER. Postoperative complication rates were comparable between the two operating techniques, although the operation time for ILR took longer and these patients required a longer hospital stay. MER should not be applied in cases with high risk of LNM.
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Metadaten
Titel
Lymph Node Retrieval is Inferior in the Modified Merendino Resection for Early Barrett’s Carcinoma: A Matched-Pair Comparison with Ivor Lewis Resection
verfasst von
Thomas Haist
Markus Mann
Christina Oetzmann von Sochaczewski
Michael Pauthner
Annette Fisseler-Eckhoff
Dietmar Lorenz
Publikationsdatum
26.05.2017
Verlag
Springer International Publishing
Erschienen in
World Journal of Surgery / Ausgabe 10/2017
Print ISSN: 0364-2313
Elektronische ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-017-4061-0

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