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Erschienen in: Breast Cancer Research 1/2010

01.05.2010 | Poster presentation

Macrophage-mediated breast cancer cell chemotaxis: the role of sphingosine kinase-1 activation

verfasst von: J Nunes, L Sauer, J Turner, J Waxman, J Sturge, D Pshezhetskiy

Erschienen in: Breast Cancer Research | Sonderheft 1/2010

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Excerpt

There is evidence to support the view that inflammatory processes are important in the development of local progression and metastases in patients with breast cancer. The sphingosine kinase-1/sphingosine-1-phosphate (SK1/S1P) pathway, which is a known mediator of inflammation, is critically implicated in breast cancer progression and chemotherapy resistance and is linked with poor prognosis. In this study we have investigated the implication of the SK1/S1P pathway in the interaction between tumour-associated macrophages and breast cancer cells. …
Metadaten
Titel
Macrophage-mediated breast cancer cell chemotaxis: the role of sphingosine kinase-1 activation
verfasst von
J Nunes
L Sauer
J Turner
J Waxman
J Sturge
D Pshezhetskiy
Publikationsdatum
01.05.2010
Verlag
BioMed Central
Erschienen in
Breast Cancer Research / Ausgabe Sonderheft 1/2010
Elektronische ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr2513

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