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11.10.2021 | Pelvis

Magnetic resonance elastography of the prostate in patients with lower urinary tract symptoms: feasibility of the modified driver at high multi-frequencies

verfasst von: Ying Deng, Zhuoya Yi, Tianhui Zhang, Bing Hu, Linqi Zhang, Kritisha Rajlawot, Sichi Kuang, Bingjun He, Arvin Arani, Jun Chen, Meng Yin, Phillip Rossman, Kevin J. Glaser, Sudhakar K. Venkatesh, Richard L. Ehman, Jin Wang

Erschienen in: Abdominal Radiology | Ausgabe 1/2022

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Abstract

Purpose

To demonstrate the feasibility and diagnostic value of high-frequency magnetic resonance elastography (MRE) for evaluation of prostatic disease in patients with lower urinary tract symptoms (LUTS).

Methods

41 patients who underwent preoperative prostate MRI and MRE with a modified driver were enrolled retrospectively from May 2016 to September 2021. All were included in the assessment of MRE image quality, using a qualitative visual inspection and a quantitative confidence map. 35 patients (prostate cancer (PCa), n = 13; non-PCa, n = 22) undergoing prostatectomy or biopsy were evaluated for the diagnostic performance of stiffness values. The confidence values and the stiffness values were analyzed by one-way analysis of variance (ANOVA) and independent samples T test, respectively. Area under the receiver operating characteristic (AUROC) analysis was performed.

Results

Through the qualitative analysis, all MRE acquisitions were successful at 60, 90, 120 and 150 Hz. The quantitative confidence values were significantly lower at 60 Hz (0.683 ± 0.055) and 90 Hz (0.762 ± 0.048) than that at 120 Hz (0.814 ± 0.049) and 150 Hz (0.840 ± 0.049), all P < 0.001. The stiffness of PCa was higher than non-PCa at 90 Hz (P = 0.008), 120 Hz (P < 0.001) and 150 Hz (P < 0.001). The AUCs were 0.773, 0.881 and 0.944, respectively.

Conclusion

Prostate MRE using the modified driver is feasible at 60–150 Hz and image quality is better at higher frequencies. Prostate MRE may be useful and helpful to evaluate prostate diseases in patients with LUTS at higher frequencies; however, further study may be warranted with larger population in future.

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Titel: Magnetic resonance elastography of the prostate in patients with lower urinary tract symptoms: feasibility of the modified driver at high multi-frequencies
verfasst von: Ying Deng
Zhuoya Yi
Tianhui Zhang
Bing Hu
Linqi Zhang
Kritisha Rajlawot
Sichi Kuang
Bingjun He
Arvin Arani
Jun Chen
Meng Yin
Phillip Rossman
Kevin J. Glaser
Sudhakar K. Venkatesh
Richard L. Ehman
Jin Wang
Publikationsdatum: 11.10.2021
Verlag: Springer US
Erschienen in: Abdominal Radiology / Ausgabe 1/2022
Print ISSN: 2366-004X
Elektronische ISSN: 2366-0058
DOI: https://doi.org/10.1007/s00261-021-03302-6

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Magnetic resonance elastography of the prostate in patients with lower urinary tract symptoms: feasibility of the modified driver at high multi-frequencies