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European Journal of Nuclear Medicine and Molecular Imaging

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01.11.2008 | Original Article

Measurement of the internal dose to families of outpatients treated with ¹³¹I for hyperthyroidism

verfasst von: S. F. Barrington, P. Anderson, A. G. Kettle, R. Gadd, W. H. Thomson, S. Batchelor, P. J. Mountford, L. K. Harding, M. J. O’Doherty

Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging | Ausgabe 11/2008

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Abstract

Objective

The aim of this study was to measure the internal dose received by family members from ingestion of radioactive contamination after outpatient therapy.

Materials and methods

Advice was given to minimise transfer of radioiodine. Home visits were made approximately 2, 7 and 21 days after treatment to measure radioactivity in the thyroids of family members. A decay correction was applied to radioactivity detected assuming ingestion had occurred at the earlier contact time, either the day of treatment or the previous home visit. An effective half-life of 6 or 7 days was used depending on age. Thyroid activity was summed if activity was found at more than one visit in excess of the amount attributable to radioactive decay. Effective dose (ED) was calculated using ICRP72.

Results and discussion

Fifty-three adults and 92 children, median age 12 (range 4–17) years participated. Median administered activity was 576 (range 329–690) MBq ¹³¹I. Thyroid activity ranged from 0 to 5.4 kBq in the adults with activity detected in 17. Maximum adult ED was 0.4 mSv. Thyroid activity ranged from 0 to 11.8 kBq in the children with activity detected in 26. The two highest values of 5.0 and 11.8 kBq occurred in children aged 5 and 14 years from different families. Eighty-five children had no activity or <1 kBq detected. ED was <0.2 mSv in 86 out of 92 children (93%). Previous published data showed 93% of children received an ED ≤0.8 mSv from external irradiation.

Conclusion

With advice, families of outpatients receiving radioiodine should be able to comply with statutory dose limits and constraints.

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Titel: Measurement of the internal dose to families of outpatients treated with 131I for hyperthyroidism
verfasst von: S. F. Barrington
P. Anderson
A. G. Kettle
R. Gadd
W. H. Thomson
S. Batchelor
P. J. Mountford
L. K. Harding
M. J. O’Doherty
Publikationsdatum: 01.11.2008
Verlag: Springer-Verlag
Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging / Ausgabe 11/2008
Print ISSN: 1619-7070
Elektronische ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-008-0892-0

Springer Medizin

Abstract

Objective

Materials and methods

Results and discussion

Conclusion

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