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Current Treatment Options in Gastroenterology

Erschienen in:

25.10.2018 | Motility (H Parkman and R Schey, Section Editors)

Migraine, Cyclic Vomiting Syndrome, and Other Gastrointestinal Disorders

verfasst von: Elliot S. Yu, MD, Yasodara Priyadharsini S.S., MBBS, Thangam Venkatesan, MD

Erschienen in: Current Treatment Options in Gastroenterology | Ausgabe 4/2018

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Abstract

Purpose of review

Cyclic vomiting syndrome (CVS) is a chronic functional gastrointestinal disorder characterized by episodic nausea and vomiting and is diagnosed using Rome IV criteria. CVS is being recognized more frequently in adults with a prevalence of 2%. It is associated with several functional disorders like autonomic dysfunction, anxiety, and depression, but the strongest association is with migraine. We will elucidate the close relationship between migraine and CVS and briefly discuss its association with other gastrointestinal disorders.

Recent findings

We highlight similarities in pathophysiology, clinical presentation, and response to medications between CVS and migraine (tricyclic antidepressants, triptans, antiepileptics). We also discuss novel therapies like CGRP inhibitors which are effective in migraine and have potential for adaptation in patients with CVS.

Summary

Using migraine as a template should enable investigators to elucidate the mechanisms underlying this disorder, develop novel therapies, and direct future research in CVS.

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Titel: Migraine, Cyclic Vomiting Syndrome, and Other Gastrointestinal Disorders
verfasst von: Elliot S. Yu, MD
Yasodara Priyadharsini S.S., MBBS
Thangam Venkatesan, MD
Publikationsdatum: 25.10.2018
Verlag: Springer US
Erschienen in: Current Treatment Options in Gastroenterology / Ausgabe 4/2018
Print ISSN: 1092-8472
Elektronische ISSN: 1534-309X
DOI: https://doi.org/10.1007/s11938-018-0202-2

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