Background
Material
The Danish notification system
The Danish MTBC Genotyping Register
Study cohort
Categorization and analysis
n (row %)* | Danes | Somalis | Greenlanders | Others ** | Total |
p-value
|
---|---|---|---|---|---|---|
Age
|
< 0.01
| |||||
0-19 years | 81 (15.1) | 271 (50.7) | 9 (1.7) | 174 (32.5) | 535 (100.0) | - |
20-39 years | 429 (20.1) | 791 (37.9) | 95 (4.6) | 772 (37.0) | 2,087 (100.0) | - |
40-59 years | 700 (58.4) | 82 (6.8) | 94 (7.8) | 323 (26.9) | 1,199 (100.0) | - |
60-79 years | 408 (69.5) | 26 (4.4) | 8 (1.4) | 145 (24.7) | 587 (100.0) | - |
≥ 80 years | 162 (89.5) | 0 (0) | 0 (0) | 19 (10.5) | 181 (100.0) | - |
Sex
|
< 0.01
| |||||
Women | 608 (31.5) | 526 (27.3) | 98 (5.1) | 698 (36.2) | 1,930 (100.0) | - |
Men | 1,172 (44.1) | 644 (24.2) | 108 (4.1) | 735 (27.6) | 2,659 (100.0) | - |
All | 1,780 (38.8) | 1,170 (25.5) | 206 (4.5) | 1,433 (31.2) | * 4,589 (100.0) |
n(column %)* | Danes | Migrants | Somalis | Greenlanders | Others** | Total |
---|---|---|---|---|---|---|
High copy number clustered (> 5 DNA bands)
| ||||||
Males | 842 (47.3) | 610 (21.4) | 299 (25.6) | 92 (44.6) | 219 (14.8) | 1,452 (31.4) |
Females | 328 (18.4) | 467 (16.4) | 222 (19.0) | 81 (39.3) | 164 (11.1) | 795 (17.2) |
All | 1,170 (65.7) | 1,077 (37.8) | 521 (44.6) | 173 (83.9) | 383 (25.9) | 2,247 (48.5) |
Low copy number clustered (≤ 5 DNA bands) | ||||||
Males | 28 (1.6) | 195 (6.8) | 122 (10.4) | 0 (0.0) | 73 (5.0) | 223 (4.8) |
Females | 9 (0.5) | 198 (6.9) | 117 (10.0) | 1 (0.5) | 80 (5.4) | 207 (4.5) |
All | 37 (2.1) | 393 (13.8) | 239 (20.4) | 1 (0.5) | 153 (10.4) | 430 (9.3) |
Non-clustered (all band numbers) | ||||||
Males | 302 (17.0) | 709 (24.9) | 223 (19.1) | 16 (7.8) | 470 (31.9) | 1,011 (21.8) |
Females | 271 (15.2) | 672 (23.6) | 187 (15.9) | 16 (7.8) | 469 (31.8) | 950 (20.5) |
All | 573 (32.2) | 1,381 (48.4) | 410 (35.0) | 32 (15.6) | 939 (63.7) | 1,954 (42.2) |
All
|
1,780 (100.0)
|
2,851 (100.0)
|
1170 (100.0)
|
206 (100.0)
|
1475 (100.0)
|
* 4,631
|
Year n(row %)* | Danes | Migrants | Somalis | Greenlanders | Others ** | Total |
---|---|---|---|---|---|---|
1992
| 86 (63.2) | 50 (36.8) | 13 (9.6) | 5 (3.7) | 32 (23.5) | 136 (100.0) |
1993
| 97 (53.3) | 85 (46.7) | 32 (17.6) | 15 (8.2) | 38 (20.9) | 182 (100.0) |
1994
| 107 (48.0) | 116 (52) | 61 (27.4) | 5 (2.2) | 50 (22.4) | 223 (100.0) |
1995
| 93 (43.5) | 121 (56.5) | 61 (28.5) | 14 (6.5) | 46 (21.5) | 214 (100.0) |
1996
| 101 (47.0) | 114 (53.0) | 63 (29.3) | 9 (4.2) | 42 (19.5) | 215 (100.0) |
1997
| 86 (34.5) | 163 (65.5) | 104 (41.8) | 13 (5.2) | 46 (18.5) | 249 (100.0) |
1998
| 112 (41.3) | 159 (58.7) | 90 (33.2) | 15 (5.5) | 54 (19.9) | 271 (100.0) |
1999
| 87 (35.7) | 157 (64.3) | 102 (41.8) | 8 (3.3) | 47 (19.3) | 244 (100.0) |
2000
| 94 (39.3) | 145 (60.7) | 91 (38.1) | 13 (5.4) | 41 (17.2) | 239 (100.0) |
2001
| 96 (46.8) | 109 (53.2) | 52 (25.4) | 20 (9.8) | 37 (18.0) | 205 (100.0) |
2002
| 73 (41.2) | 104 (58.8) | 37 (20.9) | 23 (13.0) | 44 (24.9) | 177 (100.0) |
2003
| 96 (56.1) | 75 (43.9) | 27 (15.8) | 18 (10.5) | 30 (17.5) | 171 (100.0) |
2004
| 79 (52.3) | 72 (47.7) | 27 (17.9) | 16 (10.6) | 29 (19.2) | 151 (100.0) |
All
| 1207 (45.1) | 1470 (54.9) | 760 (28.4) | 174 (6.5) | 536 (20.0) | * 2677 (100.0) |
n *
| Danes | Migrants | Somalis | Greenlanders | Others** | Total | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Age | ♀ | ♂ | Total | ♀ | ♂ | Total | Total | Total | Total | ♀ | ♂ | Total |
0-19
| 0,3 | 0,5 | 0,4 | 33,1 | 36,9 | 35,0 | 509,0 | 21,5 | 12,2 | 2,1 | 2,3 | 2,2 |
20-39
| 1,3 | 2,6 | 2,0 | 41,1 | 49,1 | 45,1 | 907,7 | 118,1 | 15,9 | 5,3 | 7,0 | 6,2 |
40-59
| 1,3 | 5,0 | 3,2 | 17,7 | 24,9 | 21,4 | 504,0 | 219,4 | 10,5 | 2,3 | 6,3 | 4,3 |
60-79
| 1,1 | 2,4 | 1,7 | 11,2 | 22,6 | 15,7 | 840,3 | 121,1 | 10,0 | 1,5 | 3,0 | 2,2 |
80+
| 1,3 | 2,4 | 1,6 | 3,3 | 10,1 | 4,9 | 0,0 | 0,0 | 5,0 | 1,3 | 2,6 | 1,7 |
All
|
1,0
|
2,7
|
1,9
|
29,6
|
37,9
|
33,6
|
725,4
|
121,0
|
13,0
|
2,9
|
4,9
|
3,9
|
* | Likely origin of clusters (based on numbers of Danes/migrants in the individual cluster) | Proportion of TB cases likely due to transmission | Odds ratio | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Danish (most Danes) | migrant (most migrants) | uncertain (even number) | |||||||||
Ethnic composition of cluster | Mixed | Danish | Mixed | Migrant | Mixed | % (95% CI) | % (95% CI) | OR (95% CI) | |||
Ehnicity of case | Migrants
n
| Danes
n
| Danes
n
| Migrants
n
| Danes
n
| Migrants
n
| Migrants
n
| Danes
n
| From migrants to Danes | From Danes to migrants | |
Origin of mixed clusters by criteria, | |||||||||||
Criteria 1 **
| 225 | 800 | 303 | 560 | 104 | 685 | 0 | 0 | 5.8 (CI 4.8-7.0) | 7.9 (CI 7.0-8.9) | 1.4 (CI 1.1-1.8) |
Criteria 2 **
| 205 | 796 | 303 | 558 | 87 | 685 | 22 | 21 | 5.0 (CI 4.0-6.1) | 7.3 (CI 6.4-8.3) | 1.5 (CI 1.2-1.9) |
Criteria 3 **
| 200 | 822 | 303 | 554 | 52 | 685 | 31 | 30 | 3.0 (CI 2.3-3.9) | 7.1 (CI 6.2-8.1) | 2.5 (CI 1.8-3.4) |
Criteria 4 **
| 179 | 761 | 303 | 523 | 45 | 685 | 83 | 98 | 2.7 (CI 2.0-3.6) | 6.5 (CI 5.6-7.5) | 2.5 (CI 1.8-3.5) |
Criteria 5 **
| 204 | 803 | 303 | 567 | 85 | 685 | 14 | 16 | 4.8 (CI 3.9-5.9) | 7.2 (CI 6.3-8.2) | 1.5 (CI 1.2-2.0) |