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Erschienen in: Archives of Osteoporosis 1/2017

01.12.2017 | Original Article

Minimal-trauma ankle fractures predominate during pregnancy: a 17-year retrospective study

verfasst von: Madhuni Herath, Phillip Wong, Anne Trinh, Carolyn A. Allan, Euan M. Wallace, Peter R. Ebeling, Peter J. Fuller, Frances Milat

Erschienen in: Archives of Osteoporosis | Ausgabe 1/2017

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Abstract

Summary

This study assessed all fractures occurring in pregnancy at a tertiary referral centre over a 17-year period. Most fractures were due to minimal trauma, and those involving the ankle were the most common. Women tended to fracture during their second and third trimesters and most required surgical intervention during pregnancy.

Purpose

To characterise fractures in pregnancy over a 17-year period at a tertiary referral health service.

Methods

Medical records at the Monash Health in Australia were examined from 2000–2016 for fractures in pregnancy using the birthing outcome system database and the tenth revision of the International Statistical Classification of Diseases and Related Health Problems coding. Site, mechanism, investigations, management and outcomes were documented.

Results

Of the 114,673 live births during this period, 33 women (mean age 30.3 ± 1.9 years) were identified with fracture in pregnancy (~ 2.9 maternal fractures/10,000 live births). Minimal-trauma fractures (MTFs) occurred in 28 women whilst 5 were due to motor vehicle accidents. Of the MTF, 2/28 (7.1%), 13/28 (46.4%) and 13/28 (46.4%) occurred in the first, second and third trimesters, respectively. MTF involved the lower limb (60.7%), upper limb (25.0%), ribs (10.7%) and clavicle (3.6%). The ankle was involved in 39.3% of MTFs. Diabetes (14.3%), asthma (10.7%) and thyroid dysfunction (7.1%) affected these women with MTF; vitamin D levels were not routinely measured. Surgical interventions requiring anaesthesia were required in 57.1% with MTF: 50.0% during their second, 31.3% in their third and 12.5% in their first trimesters; 6.3% had surgery post partum. Pre-term birth and emergency caesarean section complicated 6/28 (21.4%) of MTF pregnancies. One patient received post-partum bisphosphonate therapy; only two 2/32 (6.25%) received medical follow-up.

Conclusions

Fractures in pregnancy are uncommon. Lower limb fractures are frequently due to minimal trauma, and surgical intervention is often required. The low rate of medical follow-up in MTF is of concern and reinforces the need for greater recognition of potential osteoporosis in this population.
Literatur
1.
Zurück zum Zitat Albright F, Reifenstein EC (1949) The parathyroid glands and metabolic bone disease. Selected studies. Am J Med 7:844 Albright F, Reifenstein EC (1949) The parathyroid glands and metabolic bone disease. Selected studies. Am J Med 7:844
2.
3.
Zurück zum Zitat Kovacs CS, Ralston SH (2015) Presentation and management of osteoporosis presenting in association with pregnancy or lactation. Osteoporos Int 26(9):2223–2241CrossRefPubMed Kovacs CS, Ralston SH (2015) Presentation and management of osteoporosis presenting in association with pregnancy or lactation. Osteoporos Int 26(9):2223–2241CrossRefPubMed
4.
Zurück zum Zitat Maliha G, Morgan J, Vrahas M (2012) Transient osteoporosis of pregnancy. Injury, Int J Care Injured 43:1237–1241CrossRef Maliha G, Morgan J, Vrahas M (2012) Transient osteoporosis of pregnancy. Injury, Int J Care Injured 43:1237–1241CrossRef
5.
Zurück zum Zitat Cakmak B, Ribeiro AP, Inanir A (2016) Postural balance and the risk of falling during pregnancy. J Matern Fetal Neonatal Med 29(10):1623–1625PubMed Cakmak B, Ribeiro AP, Inanir A (2016) Postural balance and the risk of falling during pregnancy. J Matern Fetal Neonatal Med 29(10):1623–1625PubMed
6.
Zurück zum Zitat McCrory JL, Chambers AJ, Daftary A, Redfern MS (2010) Dynamic postural stability during advancing pregnancy. J Biomech 43:2434–2439CrossRefPubMed McCrory JL, Chambers AJ, Daftary A, Redfern MS (2010) Dynamic postural stability during advancing pregnancy. J Biomech 43:2434–2439CrossRefPubMed
7.
Zurück zum Zitat Sanz-Salvador L, Garcia-Perez MA, Tarin JJ, Cano A (2015) Bone metabolic changes during pregnancy: a period of vulnerability to osteoporosis and fracture. Eur J Endocrinol 172(2):R53–R65CrossRefPubMed Sanz-Salvador L, Garcia-Perez MA, Tarin JJ, Cano A (2015) Bone metabolic changes during pregnancy: a period of vulnerability to osteoporosis and fracture. Eur J Endocrinol 172(2):R53–R65CrossRefPubMed
8.
Zurück zum Zitat More C, Bettembuk P, Bhattoa HP, Balogh A (2001) The effects of pregnancy and lactation on bone mineral density. Osteoporos Int 12(9):732–737CrossRefPubMed More C, Bettembuk P, Bhattoa HP, Balogh A (2001) The effects of pregnancy and lactation on bone mineral density. Osteoporos Int 12(9):732–737CrossRefPubMed
9.
Zurück zum Zitat Chatterjee S, Kotelchuck M, Sambamoorthi U (2008) Prevalence of chronic illness in pregnancy, access to care, and health care costs: implications for interconception care. Womens Health Issues 18(6):107–116CrossRef Chatterjee S, Kotelchuck M, Sambamoorthi U (2008) Prevalence of chronic illness in pregnancy, access to care, and health care costs: implications for interconception care. Womens Health Issues 18(6):107–116CrossRef
10.
Zurück zum Zitat Mendez-Figueroa H, Dahlke JD, Vrees RA, Rouse DJ (2013) Trauma in pregnancy: an updated systematic review. Am J Obstet Gynecol 209(1):1–10CrossRefPubMed Mendez-Figueroa H, Dahlke JD, Vrees RA, Rouse DJ (2013) Trauma in pregnancy: an updated systematic review. Am J Obstet Gynecol 209(1):1–10CrossRefPubMed
11.
Zurück zum Zitat Hadji P, Boekhoff J, Hahn M, Hellmeyer L, Hars O, Kyvernitakis I (2017) Pregnancy-associated osteoporosis: a case-control study. Osteoporos Int 28(4):1393–1399CrossRefPubMed Hadji P, Boekhoff J, Hahn M, Hellmeyer L, Hars O, Kyvernitakis I (2017) Pregnancy-associated osteoporosis: a case-control study. Osteoporos Int 28(4):1393–1399CrossRefPubMed
12.
Zurück zum Zitat Kovacs C (2016) Maternal mineral and bone metabolism during pregnancy, lactation and post-weaning recovery. Physiol Rev 96(2):449–547CrossRefPubMed Kovacs C (2016) Maternal mineral and bone metabolism during pregnancy, lactation and post-weaning recovery. Physiol Rev 96(2):449–547CrossRefPubMed
13.
Zurück zum Zitat Schiff MA (2008) Pregnancy outcomes following hospitalisation for a fall in Washington state from 1987–2004. BJOG 115:1648–1654CrossRefPubMed Schiff MA (2008) Pregnancy outcomes following hospitalisation for a fall in Washington state from 1987–2004. BJOG 115:1648–1654CrossRefPubMed
14.
Zurück zum Zitat Cannada LK, Pan P, Casey BM, McIntire DD, Shafi S, Leveno KJ (2010) Pregnancy outcomes after orthopedic trauma. J Trauma 69:694–698CrossRefPubMed Cannada LK, Pan P, Casey BM, McIntire DD, Shafi S, Leveno KJ (2010) Pregnancy outcomes after orthopedic trauma. J Trauma 69:694–698CrossRefPubMed
15.
Zurück zum Zitat Dunning K, LeMasters G, Bhattacharya A (2010) A major public health issue: the high incidence of falls during pregnancy. Matern Child Health J 14:720–725CrossRefPubMed Dunning K, LeMasters G, Bhattacharya A (2010) A major public health issue: the high incidence of falls during pregnancy. Matern Child Health J 14:720–725CrossRefPubMed
16.
Zurück zum Zitat Eastell R, Reid DM, Compston J, Cooper C, Fogelman I, Francis RM, Hay SM, Hosking DJ, Purdie DW, Ralston SH, Reeve J, Russell RGG, Stevenson JC (2001) Secondary prevention of osteoporosis: when should a non-vertebral fracture be a trigger for action? Q J Med 94:575–597CrossRef Eastell R, Reid DM, Compston J, Cooper C, Fogelman I, Francis RM, Hay SM, Hosking DJ, Purdie DW, Ralston SH, Reeve J, Russell RGG, Stevenson JC (2001) Secondary prevention of osteoporosis: when should a non-vertebral fracture be a trigger for action? Q J Med 94:575–597CrossRef
17.
Zurück zum Zitat Pritchard JM, Giangregorio LM, Ioannidis G, Papaioannou A, Adachi JD, Leslie WD (2012) Ankle fractures do not predict osteoporotic fractures in women with or without fractures. Osteoporos Int 23:957–962CrossRefPubMed Pritchard JM, Giangregorio LM, Ioannidis G, Papaioannou A, Adachi JD, Leslie WD (2012) Ankle fractures do not predict osteoporotic fractures in women with or without fractures. Osteoporos Int 23:957–962CrossRefPubMed
18.
Zurück zum Zitat Biver E, Durosier C, Chevalley T, Hermann FR, Ferrari S, Rizzoli R (2015) Prior ankle fractures in postmenopausal women are associated with low areal bone mineral density and bone microstructure alterations. Osteoporos Int 26:2147–2155CrossRefPubMed Biver E, Durosier C, Chevalley T, Hermann FR, Ferrari S, Rizzoli R (2015) Prior ankle fractures in postmenopausal women are associated with low areal bone mineral density and bone microstructure alterations. Osteoporos Int 26:2147–2155CrossRefPubMed
19.
Zurück zum Zitat Stein EM, Liu XS, Nickolas TL, Cohen A, Thomas V, McMahon DJ, Zhang C, Cosman F, Nieves J, Greisberg J, Guo XE, Shane E (2011) Abnormal microarchitecture and stiffness in postmenopausal women with ankle fractures. J Clin Endocrinol Metabol 96(7):2041–2048CrossRef Stein EM, Liu XS, Nickolas TL, Cohen A, Thomas V, McMahon DJ, Zhang C, Cosman F, Nieves J, Greisberg J, Guo XE, Shane E (2011) Abnormal microarchitecture and stiffness in postmenopausal women with ankle fractures. J Clin Endocrinol Metabol 96(7):2041–2048CrossRef
20.
Zurück zum Zitat Shahtaheri SM, Aaron JE, Johnson DR, Purdie DW (1999) Changes in trabecular bone architecture in women during pregnancy. Br J Obstet Gynaecol 106(5):432–438CrossRefPubMed Shahtaheri SM, Aaron JE, Johnson DR, Purdie DW (1999) Changes in trabecular bone architecture in women during pregnancy. Br J Obstet Gynaecol 106(5):432–438CrossRefPubMed
21.
Zurück zum Zitat Wisser J, Florio I, Neff M, Konig V, Huch R, Huch A, Mandach UV (2005) Changes in bone density and metabolism in pregnancy. Acta Obstet Gynecol Scand 84:349–354CrossRefPubMed Wisser J, Florio I, Neff M, Konig V, Huch R, Huch A, Mandach UV (2005) Changes in bone density and metabolism in pregnancy. Acta Obstet Gynecol Scand 84:349–354CrossRefPubMed
22.
Zurück zum Zitat Ulrich U, Miller PB, Eyre DR, Chesnut CH, Schlebusch H, Soues MR (2003) Bone remodelling and bone mineral density during pregnancy. Arch Gynecol Obstet 268:309–316CrossRefPubMed Ulrich U, Miller PB, Eyre DR, Chesnut CH, Schlebusch H, Soues MR (2003) Bone remodelling and bone mineral density during pregnancy. Arch Gynecol Obstet 268:309–316CrossRefPubMed
23.
Zurück zum Zitat Styczynska H, Lis K, Sobanska I, Pater A, Pollak J, Mankowska A (2009) Bone turnover markers and osteoprotegerin in uncomplicated pregnancy. Electron J Int Fed Clin Chem Lab Med 19(4):193–202 Styczynska H, Lis K, Sobanska I, Pater A, Pollak J, Mankowska A (2009) Bone turnover markers and osteoprotegerin in uncomplicated pregnancy. Electron J Int Fed Clin Chem Lab Med 19(4):193–202
24.
Zurück zum Zitat Dieguez M, Herrero A, Avello N, Suarez P, Delgado E, Menendez E (2016) Prevalence of thyroid dysfunction in women in early pregnancy: does it increase with maternal age? Clin Endocrinol 84(1):121–126CrossRef Dieguez M, Herrero A, Avello N, Suarez P, Delgado E, Menendez E (2016) Prevalence of thyroid dysfunction in women in early pregnancy: does it increase with maternal age? Clin Endocrinol 84(1):121–126CrossRef
25.
Zurück zum Zitat Negro R, H MJ (2011) Thyroid disease in pregnancy. Best Pract Res Clin Endocrinol Metab 25(6):927–943CrossRefPubMed Negro R, H MJ (2011) Thyroid disease in pregnancy. Best Pract Res Clin Endocrinol Metab 25(6):927–943CrossRefPubMed
26.
27.
Zurück zum Zitat World Health Organization (2016) Diabetes country profiles 2016—Australia, Geneva World Health Organization (2016) Diabetes country profiles 2016—Australia, Geneva
28.
Zurück zum Zitat Australian Bureau of Statistics (2015) National health survey: first results, 2014–15. Cat. No. 4363.0.55.001;. ABS, Canberra Australian Bureau of Statistics (2015) National health survey: first results, 2014–15. Cat. No. 4363.0.55.001;. ABS, Canberra
29.
Zurück zum Zitat Templeton M, Pieris-Caldwell I (2008) Gestational diabetes mellitus in Australia, 2005-06. Cat. no. CVD 44. Australian Institute of Health and Welfare Templeton M, Pieris-Caldwell I (2008) Gestational diabetes mellitus in Australia, 2005-06. Cat. no. CVD 44. Australian Institute of Health and Welfare
30.
Zurück zum Zitat Australian Institute of Health and Welfare (2016) Australia’s mothers and babies 2014: in brief. Perinatal statistics series no. 32 Cat no. PER 87. AIHW, Canberra Australian Institute of Health and Welfare (2016) Australia’s mothers and babies 2014: in brief. Perinatal statistics series no. 32 Cat no. PER 87. AIHW, Canberra
31.
32.
Zurück zum Zitat Baldwin EA, Borowski KS, Brost BC, Rose CH (2015) Antepartum nonobstetrical surgery at >/= 23 weeks’ gestation and risk for preterm delivery. Am J Obstet Gynecol 212(232):e1–e5 Baldwin EA, Borowski KS, Brost BC, Rose CH (2015) Antepartum nonobstetrical surgery at >/= 23 weeks’ gestation and risk for preterm delivery. Am J Obstet Gynecol 212(232):e1–e5
33.
Zurück zum Zitat Bhattee G, Rahman MS, Rahman J (2009) Open reduction and internal fixation of an acetabular fracture in pregnancy: a case report. Curr Orthop Pract 20(3):329–330CrossRef Bhattee G, Rahman MS, Rahman J (2009) Open reduction and internal fixation of an acetabular fracture in pregnancy: a case report. Curr Orthop Pract 20(3):329–330CrossRef
34.
Zurück zum Zitat American College of Obstetricians and Gynecologists (2017) Nonobstetric surgery during pregnancy. Committee Opinion No. 696. Obstet Gynecol 129:777–778CrossRef American College of Obstetricians and Gynecologists (2017) Nonobstetric surgery during pregnancy. Committee Opinion No. 696. Obstet Gynecol 129:777–778CrossRef
35.
Zurück zum Zitat Phillips AJ, Ostlere SJ, Smith R (2000) Pregnancy-associated osteoporosis: does the skeleton recover? Osteoporos Int 11:449–454CrossRefPubMed Phillips AJ, Ostlere SJ, Smith R (2000) Pregnancy-associated osteoporosis: does the skeleton recover? Osteoporos Int 11:449–454CrossRefPubMed
36.
Zurück zum Zitat Salles JP (2016) Bone metabolism during pregnancy. Ann Endocrinol 77:163–168CrossRef Salles JP (2016) Bone metabolism during pregnancy. Ann Endocrinol 77:163–168CrossRef
37.
Zurück zum Zitat Pediatrics AAo (2012) Breastfeeding and the use of human milk. Pediatrics 129(3):e827–e841CrossRef Pediatrics AAo (2012) Breastfeeding and the use of human milk. Pediatrics 129(3):e827–e841CrossRef
38.
Zurück zum Zitat Patlas N, Golomb G, Yaffe P, Pinto T, Breuer E, Ornoy A (1999) Transplacental effects of bisphosphonates on fetal skeletal ossification and mineralization in rats. Teratology 60:68–73CrossRefPubMed Patlas N, Golomb G, Yaffe P, Pinto T, Breuer E, Ornoy A (1999) Transplacental effects of bisphosphonates on fetal skeletal ossification and mineralization in rats. Teratology 60:68–73CrossRefPubMed
Metadaten
Titel
Minimal-trauma ankle fractures predominate during pregnancy: a 17-year retrospective study
verfasst von
Madhuni Herath
Phillip Wong
Anne Trinh
Carolyn A. Allan
Euan M. Wallace
Peter R. Ebeling
Peter J. Fuller
Frances Milat
Publikationsdatum
01.12.2017
Verlag
Springer London
Erschienen in
Archives of Osteoporosis / Ausgabe 1/2017
Print ISSN: 1862-3522
Elektronische ISSN: 1862-3514
DOI
https://doi.org/10.1007/s11657-017-0380-x

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