Erschienen in:
01.04.2010 | Original paper
Moderate physical activity and breast cancer risk: the effect of menopausal status
verfasst von:
Angélica Ángeles-Llerenas, Carolina Ortega-Olvera, Edelmiro Pérez-Rodríguez, Jesús Pablo Esparza-Cano, Eduardo Lazcano-Ponce, Isabelle Romieu, Gabriela Torres-Mejía
Erschienen in:
Cancer Causes & Control
|
Ausgabe 4/2010
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Abstract
Introduction
It has been suggested that both moderate- and vigorous-intensity physical activity reduces the risk of breast cancer. However, the effect of moderate-intensity physical activity on breast cancer risk has not been consistently evaluated by menopausal status and has not been evaluated in Mexican women.
Objective
To evaluate the effect of moderate-intensity physical activity (h/week and MET-h/week) on the risk of breast cancer by menopausal status in Mexican women.
Methods
A population-based case–control study was conducted in Mexico. One thousand incident cases and 1,074 matched controls to cases by 5 years of age, site and health institution participated in the study. Women provided information on health, diet and physical activity by means of an in-person interview. Anthropometric measurements and blood samples were obtained from all women. A conditional logistic regression model was used to assess this association.
Results
Participating in moderate-intensity physical activity decreased the risk of BC in both pre- and postmenopausal women (OR = 0.96; 95% CI 0.92.–0.99; OR = 0.90; 95% CI 0.86–0.93, respectively) for every 3 h per week of moderate-intensity physical activity. There was a statistically significant modification effect by menopausal status (p = 0.009).
Conclusions
Strategies need to be identified that will engage women in physical activity programs.