nach oben

Neurological Sciences

Erschienen in:

10.07.2020 | Original Article

Modulation of the excitatory phase following the cutaneous silent period by vibration

verfasst von: Ayşegül Gündüz, Selahattin Ayas, Markus Kofler, Şenay Aydın, Meral Erdemir Kızıltan

Erschienen in: Neurological Sciences | Ausgabe 2/2021

Einloggen, um Zugang zu erhalten

Abstract

Introduction

The post-inhibition excitatory phase (E3) of the cutaneous silent period (CSP) is attributed to the resynchronization of motoneuron activity following the inhibitory period but there is also evidence that a somatosensory startle reflex may contribute to this phase. We hypothesized that the startle reflex component contained in E3 will decrease during vibration.

Methods

Sixteen healthy individuals were included in the study. CSP was recorded from slightly contracted right thenar muscles after painful index finger stimulation, before, during, and immediately after vibration. The values of the percentage change of E3 relative to pre-stimulus baseline (E3%) were compared before, during, and after vibration for each individual.

Results

There was a reduction in E3% during vibration and the values returned to normal immediately after vibration (153.1 ± 43.5%, 115.2 ± 30.2%, 154.9 ± 68.2%, respectively; p = 0.030).

Discussion

E3 is reduced during vibration in healthy individuals, presumably due to suppression of a reflex component, which is superimposed upon the known resynchronization of motoneurons.

Kofler M, Müller J, Reggiani L, Valls-Sol’e J (2001) Influence of age on auditory startle responses in humans. NeurosciLett 307(2):65–68

Kofler M, Poustka K (2005) Ipsi- and contralateral exteroceptive EMG modulation in uni and bilaterally activated thenar muscles. Clin Neurophysiol 116:300–307CrossRef

Kumru H, Opisso E, Valls-Solé J, Kofler M (2009) The effect of a prepulse stimulus on the EMG rebound following the cutaneous silent period. J Physiol 587(3):587–595CrossRef

Müller J, Kofler M, Wenning GK, Seppi K, Valls-Solé J, Poewe W (2003) Auditory startle response in cervical dystonia. Mov Disord 18(12):1522–1526

Hill BD, Blumenthal TD (2005) Inhibition of acoustic startle using different mechano receptive channels. Percept Psychophys 67:741–747CrossRef

Kofler M (2003) Functional organization of exteroceptive inhibition following nociceptive electrical fingertip stimulation in humans. Clin Neurophysiol 114:973–980CrossRef

Kofler M (2004) Influence of transcutaneous electrical nevre stimulation on cutaneous silent periods in humans. Neurosci Lett 360:69–72CrossRef

Stokic DS, Kofler M, Stetkarova I, Leis AA (2019) Exteroceptive suppression of voluntary activity in thenar muscles by cutaneous stimulation: how many trials should be averaged? Clin NeurolNeurosurg 184:105452CrossRef

Kofler M, Kumru H, Stetkarova I, Schindler C, Fuhr P (2007) Muscle force up to 50% of maximum does not affect cutaneous silent periods in thenar muscles. Clin Neurophysiol 118:2025–2030CrossRef

10.

Rodi Z, Springer C (2011) Influence of muscle contraction and intensity of stimulation on the cutaneous silent period. Muscle Nerve 43:324–328CrossRef

11.

Kofler M, Leis AA, Valls-Sole J (2019) Cutaneous silent periods - part 1: update on physiological mechanisms. Clin Neurophysiol 130:588–603CrossRef

12.

Kranz H, Adorjani C, Baumgartner G (1973) The effect of nociceptive cutaneous stimuli on human motoneurons. Brain 96:571–590CrossRef

13.

Gassel M, Ott KH (1970) Local signand late effect on motor neuron excitability of cutaneous stimulation in man. Brain 93:95–106CrossRef

14.

Aydın S, Kofler M, Bakuy Y, Gunduz A, Kızıltan M (2019) Effects of vibration on cutaneous silent period. Exp Brain Res 237:911–918CrossRef

15.

De Gail P, Lance JW, Neilson PD (1966) Differential effects on tonic and phasic reflex mechanisms produced by vibration of muscles in man. J Neurol Neurosurg Psychiatry 29:1–11CrossRef

16.

Gillies JD, Lance JW, Neilson PD, Tassinari CA (1969) Presynaptic inhibition of the monosynaptic reflex by vibration. J Physiol 205:329–339CrossRef

17.

Lapole T, Temesi J, Arnal PJ, Gimenez P, Petitjean M, Millet GY (2015) Modulation of soleus corticospinal excitability during Achilles tendon vibration. Exp Brain Res 233:2655–2662CrossRef

18.

Uncini A, Kujirai T, Gluck B, Pullman S (1991) Silent period induced by cutaneous stimulation. Electroencephalogr Clin Neurophysiol 81:344–352CrossRef

19.

Pierrot-Deseilligny E, Burke D (2012) The circuitry of the human spinal cord. Spinal and corticospinal mechanisms of movement. Cambridge University Press, CambridgeCrossRef

20.

Claus D, Mills KR, Murray NM (1988) The influence of vibration on the excitability of alpha motoneurones. Electroencephalogr Clin Neurophysiol 69:431–436CrossRef

21.

Mosier EM, Herda TJ, Trevino MA, Miller JD (2017) The influence of prolonged vibration on motor unit behavior. Muscle Nerve 55:500–507CrossRef

22.

Xu L, Negro F, Xu Y, Rabotti C, Schep G, Farina D, Mischi M (2018) Does vibration superimposed on low-level isometric contraction alter motor unit recruitment strategy? J Neural Eng 15:066001CrossRef

23.

Griffin L, Garland SJ, Ivanova T, Gossen ER (2001) Muscle vibration sustains motor unit firing rate during submaximal isometric fatigue in humans. J Physiol 535:929–936CrossRef

24.

Blumenthal TD, Gescheider GA (1987) Modification of the acoustic startle reflex by a tactile prepulse: the effects of stimulus onset asynchrony and prepulse intensity. Psychophysiology 24(3):320–327CrossRef

25.

Lovelace CT, Blumenthal TD (1991) Hand dominance and the modification of the acoustically elicited startle response by a vibrotactile prepulse. Psychobiology 19(3):265–273

26.

Pantaleo T, Duranti R, Bellini F (1986) Effects of vibratory stimulation on muscular pain threshold and blink response in human subjects. Pain 24(2):239–250CrossRef

27.

Garcia-Rill E, Saper CB, Rye DB, Kofler M, Nonnekes J, Lozano A, Valls-Solé J, Hallett M (2019) Focus on the pedunculopontine nucleus. Consensus review from the May 2018 brainstem society meeting in Washington, DC, USA. Clin Neurophysiol 130(6):925–940CrossRef

28.

Serrao M, Parisi L, Valente G, Martini A, Fattapposta F, Pierelli F, Rossi P (2002) L-Dopa decreases cutaneous nociceptive inhibition of motor activity in Parkinson’s disease. Acta Neurol Scand 105:196–201CrossRef

29.

Isoardo G, Stella M, Cocito D, Risso D, Migliaretti G, Cauda F, Palmitessa A, Faccani G, Ciaramitaro P (2012) Neuropathic pain in post-burn hypertrophic scars: a psychophysical and neurophysiological study. Muscle Nerve 45:883–890CrossRef

30.

Tekatas A, Arican O, Guler S, Aynaci O, Dincer N (2014) Pruritus: do ad fibers play a role? J Dermatol 41:98–101CrossRef

31.

Baek SH, Seok HY, Koo YS, Kim BJ (2016) Lengthened cutaneous silent period in fibromyalgia suggesting central sensitization as a pathogenesis. PLoS One 11:e0149248CrossRef

32.

Koo YS, Park HR, Joo BE, Choi JY, Jung KY, Park KW, Cho SC, Kim BJ (2010) Utility of the cutaneous silent period in the evaluation of carpal tunnel syndrome. Clin Neurophysiol 121:1584–1588CrossRef

33.

de Leonni Stanonik M, Licata CA, Kofler M (2010) The influence of age and sex on cutaneous silent periods. Clin Neurophysiol 121:S272-S

34.

Mota IA, Fernandes JB, Cardoso MN, Sala-Blanch X, Kofler M, Valls-Solé J (2015) Temporal profile of the effects of regional anesthesia on the cutaneous reflexes of foot muscles. Exp Brain Res 233:2587–2596CrossRef

35.

Ludewig K, Ludewig S, Seitz A, Obrist M, Geyer MA, Vollenweider FX (2003) The acoustic startle reflex and its modulation: effects of age and gender in humans. Biol Psychol 63(3):311–323CrossRef

36.

Ellwanger J, Geyer MA, Braff DL (2003) The relationship of age to prepulse inhibition and habituation of the acoustic startle response. Biol Psychol 62:175–195CrossRef

37.

Kofler M, Müller J, Valls-Solé J (2006) Auditory startle responses as a probe of brainstem function in healthy subjects and patients with movement disorders. Suppl Clin Neurophysiol 58:232-248

Titel: Modulation of the excitatory phase following the cutaneous silent period by vibration
verfasst von: Ayşegül Gündüz
Selahattin Ayas
Markus Kofler
Şenay Aydın
Meral Erdemir Kızıltan
Publikationsdatum: 10.07.2020
Verlag: Springer International Publishing
Erschienen in: Neurological Sciences / Ausgabe 2/2021
Print ISSN: 1590-1874
Elektronische ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-020-04557-5

Leitlinien kompakt für die Neurologie

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Neurologie

Akuter Schwindel: Wann lohnt sich eine MRT?

28.04.2024 Schwindel Nachrichten

Akuter Schwindel stellt oft eine diagnostische Herausforderung dar. Wie nützlich dabei eine MRT ist, hat eine Studie aus Finnland untersucht. Immerhin einer von sechs Patienten wurde mit akutem ischämischem Schlaganfall diagnostiziert.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Frühe Alzheimertherapie lohnt sich

25.04.2024 AAN-Jahrestagung 2024 Nachrichten

Ist die Tau-Last noch gering, scheint der Vorteil von Lecanemab besonders groß zu sein. Und beginnen Erkrankte verzögert mit der Behandlung, erreichen sie nicht mehr die kognitive Leistung wie bei einem früheren Start. Darauf deuten neue Analysen der Phase-3-Studie Clarity AD.

Viel Bewegung in der Parkinsonforschung

25.04.2024 Parkinson-Krankheit Nachrichten

Neue arznei- und zellbasierte Ansätze, Frühdiagnose mit Bewegungssensoren, Rückenmarkstimulation gegen Gehblockaden – in der Parkinsonforschung tut sich einiges. Auf dem Deutschen Parkinsonkongress ging es auch viel um technische Innovationen.

Update Neurologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Abstract

Introduction

Methods

Results

Discussion

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 2/2021

Patient characteristics with negative diffusion-weighted imaging findings in acute lateral medullary infarction

Down’s syndrome and COVID-19: risk or protection factor against infection? A molecular and genetic approach

Serum level of lipoprotein-associated phospholipase A2 is a potential biomarker of vertebrobasilar dolichoectasia and its progression to cerebral infarction

DAPT score: predictive model of dual-antiplatelet therapy for acute cerebral infarction

Multimodal evaluation of the cerebrovascular reserve in Neurofibromatosis type 1 patients with Moyamoya syndrome