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Erschienen in: European Spine Journal 3/2006

01.08.2006 | Review

Molecular therapy of the intervertebral disc

verfasst von: S. Tim Yoon, Nilpesh M. Patel

Erschienen in: European Spine Journal | Sonderheft 3/2006

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Abstract

Disc degeneration is the loss of the normal nucleus pulposus disc matrix to a more fibrotic and less cartilaginous structure. This change in disc micro-anatomy can be associated with pain and deformity, however, prevention and treatment options of disc degeneration are currently limited. Much research is going on to understand intervertebral discs at a molecular/ cellular level in hopes of creating clinically applicable options for treating disc degeneration. This review article will give insight into the current and developing status of treating intervertebral disc degeneration from a molecular standpoint.
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Zurück zum Zitat Paul R, Haydon RC, Cheng H et al (2003) Potential use of sox9 gene therapy for intervertebral degenerative disc disease. Spine 28(8):755–763PubMedCrossRef Paul R, Haydon RC, Cheng H et al (2003) Potential use of sox9 gene therapy for intervertebral degenerative disc disease. Spine 28(8):755–763PubMedCrossRef
Metadaten
Titel
Molecular therapy of the intervertebral disc
verfasst von
S. Tim Yoon
Nilpesh M. Patel
Publikationsdatum
01.08.2006
Verlag
Springer-Verlag
Erschienen in
European Spine Journal / Ausgabe Sonderheft 3/2006
Print ISSN: 0940-6719
Elektronische ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-006-0155-3

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