Introduction
Materials and methods
Population and study protocol
MRI acquisition
Carotid vessel wall thickness
Carotid pulse wave velocity
Cerebral white matter lesions
Image analysis
Carotid vessel wall thickness
Pulse wave velocity
White matter lesions
Statistical analysis
Results
Age at magnetic resonance imaging (MRI) (years) | 61 ± 11 |
Age range (min.–max.) | (37–82) |
Days between MI and vessel wall MRI scan (days) | 299 ± 144 |
Culprit vessel at MI | |
Left anterior descending artery | 5 (25 %) |
Right coronary artery | 13 (65 %) |
Circumflex artery | 2 (10 %) |
Peak troponin T values (µg/l) | 3.8 ± 2.4 |
Male gender, n (%) | 18 (90 %) |
BMI (kg/m2) | 26 ± 3 |
Brachial blood pressure (mmHg) | |
Systolic | 125 ± 23 |
Diastolic | 76 ± 12 |
Heart rate (beats per minute) | 74 ± 16 |
Patients with arterial hypertension, n (%) | 10 (50 %) |
Patients with diabetes mellitus, n (%) | 2 (10 %) |
Smokers, n (%) | 8 (40 %) |
Total cholesterol (mmol/l) | 5.09 ± 1.17 |
Vessel wall morphology and function
Myocardial infarction patients (n = 20) | |
---|---|
Trajectory carotid artery, mm | 147 ± 20 |
PWV carotid artery, m/s | 7.0 ± 2.2 |
Mean vessel wall thickness carotid artery, mm | 1.41 ± 0.3 |
Maximal vessel wall thickness carotid artery, mm | 1.73 ± 0.4 |
White matter lesions
Periventricular lesion score | Subcortical lesion score | |||
---|---|---|---|---|
Anterior | Lateral | Posterior | ||
Score 0 | 0 (0) | 0 (0) | 0 (0) | 3 (20) |
Score 1 | 11 (73) | 11 (73) | 14 (93) | 5 (33) |
Score 2 | 3 (20) | 3 (20) | 1 (7) | 6 (40) |
Score 3 | 1 (7) | 1 (7) | 0 (0) | 1 (7) |