Erschienen in:
11.09.2023 | Letter to the Editor
Mortality risk factors in newly diagnosed diabetic cardiac autonomic neuropathy
verfasst von:
Bruce A. Chase, Sylwia Pocica, Roberta Frigerio, Katerina Markopoulou, Demetrius M. Maraganore, Navamon Aunaetitrakul, Alexander Epshteyn, Alexandru C. Barboi
Erschienen in:
Clinical Autonomic Research
|
Ausgabe 6/2023
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Excerpt
Cardiac autonomic neuropathy (CAN) diagnosis is based on clinical symptoms and supported by noninvasive autonomic reflex tests that establish extent and severity of involvement [
1,
2]. CAN is associated with increased mortality [
3], cardiovascular disease [
4], and chronic kidney disease [
5]. If its clinical, genetic, and comorbidity risk factors [
6‐
8] contribute to pathophysiological processes causing its progression, they may also be mortality risk factors. To inform design of interventions that may reduce mortality in CAN patients living with diabetes, we asked whether genetic variants, clinical attributes, and autonomic testing findings present
at the time of CAN diagnosis are associated with increased mortality. …
