Erschienen in:
01.12.2015 | Brief Communication
Multiple sclerosis and Parkinson’s disease: the two faces of neurodegeneration. Report of the first Greek case and review of the literature
verfasst von:
Anastasia Bougea, Elisabeth Kapaki, George P. Paraskevas, Kostas Kilidireas, Elisabeth Andreadou
Erschienen in:
Neurological Sciences
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Ausgabe 12/2015
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Abstract
There is still an open debate whether multiple sclerosis (MS) lesions can cause parkinsonian symptoms, or the coexistence of both diseases in the same patient is accidental. Moreover, α-synuclein (α Syn), the hallmark of Parkinson’s disease (PD) seems also to play a crucial role in MS. So far, 42 cases of co-occurrence of parkinsonism and MS have been reported, but CSF α Syn measurement is lacking. To our knowledge, we report the first case with concomitant MS and PD diagnosis based on both clinico-radiological and CSF α Syn findings and review of literature.