Erschienen in:
03.11.2022 | REVIEW
Multivariable regression: understanding one of medicine’s most fundamental statistical tools
verfasst von:
Nathan H. Varady, Ayoosh Pareek, Christina M. Eckhardt, Riley J. Williams III, Sophia J. Madjarova, Matthieu Ollivier, R. Kyle Martin, Jón Karlsson, Benedict U. Nwachukwu
Erschienen in:
Knee Surgery, Sports Traumatology, Arthroscopy
|
Ausgabe 1/2023
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Abstract
Multivariable regression is a fundamental tool that drives observational research in orthopaedic surgery. However, regression analyses are not always implemented correctly. This study presents a basic overview of regression analyses and reviews frequent points of confusion. Topics include linear, logistic, and time-to-event regressions, causal inference, confounders, overfitting, missing data, multicollinearity, interactions, and key differences between multivariable versus multivariate regression. The goal is to provide clarity regarding the use and interpretation of multivariable analyses for those attempting to increase their statistical literacy in orthopaedic research.