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Medical Oncology

Erschienen in:

01.06.2019 | Review Article

N-Glycosylation in progression of skin cancer

verfasst von: Ling Tang, Xiaoping Chen, Xu Zhang, Yeye Guo, Juan Su, Jianglin Zhang, Cong Peng, Xiang Chen

Erschienen in: Medical Oncology | Ausgabe 6/2019

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Abstract

Skin cancer can be classified as cutaneous malignant melanoma, basal cell carcinoma, and squamous cell carcinoma. Due to the high level of morbidity and mortality, skin cancer has become a global public health issue worldwide while the pathogenesis of skin cancer is still unclear. It is necessary to further identify the pathogenesis of skin cancer and find candidate targets to diagnose and treat skin cancer. A variety of factors are known to be associated with skin cancer including N-glycosylation, which partly explained the malignant behaviors of skin cancer. In this review, we retrieved databases such as PubMed and Web of Science to elucidate its relationship between glycosylation and skin cancer. We summarized some key glycosyltransferases and proteins during the process of N-glycosylation related to skin cancer, which was helpful to unmask the additional mechanism of skin cancer and find some novel targets of skin cancer.

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Titel: N-Glycosylation in progression of skin cancer
verfasst von: Ling Tang
Xiaoping Chen
Xu Zhang
Yeye Guo
Juan Su
Jianglin Zhang
Cong Peng
Xiang Chen
Publikationsdatum: 01.06.2019
Verlag: Springer US
Erschienen in: Medical Oncology / Ausgabe 6/2019
Print ISSN: 1357-0560
Elektronische ISSN: 1559-131X
DOI: https://doi.org/10.1007/s12032-019-1270-4

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N-Glycosylation in progression of skin cancer

Abstract

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