Erschienen in:
01.02.2003 | Review
Natural killer cells and autoimmunity
verfasst von:
Anthony R French, Wayne M Yokoyama
Erschienen in:
Arthritis Research & Therapy
|
Ausgabe 1/2003
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Abstract
Autoimmune diseases are often characterized as clinical syndromes caused by the inappropriate activation of T or B cells resulting in systemic or organ-specific damage. However, studies support a role for the innate immune system, and in particular natural killer (NK) cells, in stimulating or suppressing autoimmunity. This review focuses on recent research elucidating a potential immunoregulatory role for NK cells in modulating T and B cell-mediated autoimmunity.