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Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy 3/2019

19.06.2018 | Knee

Neither significant osteoarthritic changes nor deteriorating subjective outcomes occur after hybrid fixation of osteochondritis dissecans in the young adult

verfasst von: L. Chadli, C. Steltzlen, P. Beaufils, C. Toanen, N. Pujol

Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy | Ausgabe 3/2019

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Abstract

Purpose

The goal of the fixation of painful osteochondritis dissecans of the femoral condyles in adults is to integrate the osteochondral fragment and thus achieve a normal hyaline cartilaginous coverage. The addition of a biological process to primary fixation may result in improved fragment integration (hybrid fixation). Osteochondral plugs may fulfil this role. The aim of this study was to evaluate long-term clinical and radiological results after hybrid fixation of unstable osteochondritis dissecans. The hypothesis was that the rate of secondary osteoarthritis would be low.

Methods

Nine patients treated by hybrid fixation were retrospectively reviewed at a median follow-up of 10.1 years (range 7–14). The median age at surgery was 21 (range 17–28). Six of them were evaluated as ICRS grade II and three, as ICRS grade III. The mean surface of the lesion was 4.5 cm2. All patients were followed up clinically (IKDC, KOOS, Lysholm) and radiologically [Kellgren–Lawrence score (KL)].

Results

During arthroscopic assessment at the time of screw removal (3 months after surgery), the fragments were stable, and autograft plugs were all well integrated. At the most recent follow-up visit, the median IKDC score was 85.8 (range 51.72–100), the KOOS score was 87.7 (52.4–100), and the Lysholm scale score was 89.8 (77–100). In 7 out of 9 patients, radiographs showed a joint space KL grade of 0 or 1.

Conclusion

Hybrid fixation for treating osteochondritis dissecans lesions of the femoral condyles using mechanical and biological fixation provides healing of the osteochondral fragments with good long-term outcomes. No significant osteoarthritic change was seen with this technique at a mid-term follow-up.

Level of evidence

IV—case series.
Literatur
1.
Zurück zum Zitat Anderson AF, Pagnani MJ (1997) Osteochondritis dissecans of the femoral condyles. Long-term results of excision of the fragment. Am J Sports Med 25:830–834CrossRefPubMed Anderson AF, Pagnani MJ (1997) Osteochondritis dissecans of the femoral condyles. Long-term results of excision of the fragment. Am J Sports Med 25:830–834CrossRefPubMed
2.
Zurück zum Zitat Berlet GC, Mascia A, Miniaci A (1999) Treatment of unstable osteochondritis dissecans lesions of the knee using autogenous osteochondral grafts (mosaicplasty). Arthroscopy 15:312–316CrossRefPubMed Berlet GC, Mascia A, Miniaci A (1999) Treatment of unstable osteochondritis dissecans lesions of the knee using autogenous osteochondral grafts (mosaicplasty). Arthroscopy 15:312–316CrossRefPubMed
3.
Zurück zum Zitat Brittberg M, Winalski CS (2003) Evaluation of cartilage injuries and repair. J Bone Jt Surg Am 85:58–69CrossRef Brittberg M, Winalski CS (2003) Evaluation of cartilage injuries and repair. J Bone Jt Surg Am 85:58–69CrossRef
4.
Zurück zum Zitat Cahill null (1995) Osteochondritis dissecans of the knee: treatment of juvenile and adult forms. J Am Acad Orthop Surg 3:237–247CrossRef Cahill null (1995) Osteochondritis dissecans of the knee: treatment of juvenile and adult forms. J Am Acad Orthop Surg 3:237–247CrossRef
5.
Zurück zum Zitat Chadli L, Steltzlen C, Toanen C, Boisrenoult P, Beaufils P, Pujol N (2018) Hybrid fixation in adult osteochondritis dissecans of the knee. Orthop Traumatol Surg Res 104:223–225CrossRefPubMed Chadli L, Steltzlen C, Toanen C, Boisrenoult P, Beaufils P, Pujol N (2018) Hybrid fixation in adult osteochondritis dissecans of the knee. Orthop Traumatol Surg Res 104:223–225CrossRefPubMed
6.
Zurück zum Zitat Christensen BB, Foldager CB, Jensen J, Jensen NC, Lind M (2016) Poor osteochondral repair by a biomimetic collagen scaffold: 1- to 3-year clinical and radiological follow-up. Knee Surg Sports Traumatol Arthrosc 24:2380–2387CrossRefPubMed Christensen BB, Foldager CB, Jensen J, Jensen NC, Lind M (2016) Poor osteochondral repair by a biomimetic collagen scaffold: 1- to 3-year clinical and radiological follow-up. Knee Surg Sports Traumatol Arthrosc 24:2380–2387CrossRefPubMed
7.
Zurück zum Zitat Delcogliano M, de Caro F, Scaravella E, Ziveri G, De Biase CF, Marotta D, Marenghi P, Delcogliano A (2014) Use of innovative biomimetic scaffold in the treatment for large osteochondral lesions of the knee. Knee Surg Sports Traumatol Arthrosc 22:1260–1269PubMed Delcogliano M, de Caro F, Scaravella E, Ziveri G, De Biase CF, Marotta D, Marenghi P, Delcogliano A (2014) Use of innovative biomimetic scaffold in the treatment for large osteochondral lesions of the knee. Knee Surg Sports Traumatol Arthrosc 22:1260–1269PubMed
8.
Zurück zum Zitat Filardo G, Kon E, Perdisa F, Tetta C, Di Martino A, Marcacci M (2015) Arthroscopic mosaicplasty: long-term outcome and joint degeneration progression. Knee 22:36–40CrossRefPubMed Filardo G, Kon E, Perdisa F, Tetta C, Di Martino A, Marcacci M (2015) Arthroscopic mosaicplasty: long-term outcome and joint degeneration progression. Knee 22:36–40CrossRefPubMed
9.
Zurück zum Zitat Gross AE, Shasha N, Aubin P (2005) Long-term followup of the use of fresh osteochondral allografts for posttraumatic knee defects. Clin Orthop Relat Res 435:79–87CrossRef Gross AE, Shasha N, Aubin P (2005) Long-term followup of the use of fresh osteochondral allografts for posttraumatic knee defects. Clin Orthop Relat Res 435:79–87CrossRef
10.
Zurück zum Zitat Hangody L, Füles P (2003) Autologous osteochondral mosaicplasty for the treatment of full-thickness defects of weight-bearing joints: ten years of experimental and clinical experience. J Bone Jt Surg Am 85-A(Suppl 2):25–32CrossRef Hangody L, Füles P (2003) Autologous osteochondral mosaicplasty for the treatment of full-thickness defects of weight-bearing joints: ten years of experimental and clinical experience. J Bone Jt Surg Am 85-A(Suppl 2):25–32CrossRef
11.
Zurück zum Zitat Hangody L, Vásárhelyi G, Hangody LR, Sükösd Z, Tibay G, Bartha L, Bodó G (2008) Autologous osteochondral grafting–technique and long-term results. Injury 39(Suppl 1):S32–S39CrossRefPubMed Hangody L, Vásárhelyi G, Hangody LR, Sükösd Z, Tibay G, Bartha L, Bodó G (2008) Autologous osteochondral grafting–technique and long-term results. Injury 39(Suppl 1):S32–S39CrossRefPubMed
13.
Zurück zum Zitat Knutsen G, Drogset JO, Engebretsen L, Grøntvedt T, Ludvigsen TC, Løken S, Solheim E, Strand T, Johansen O (2016) A randomized multicenter trial comparing autologous chondrocyte implantation with microfracture: long-term follow-up at 14 to 15 years. J Bone Jt Surg Am 98:1332–1339CrossRef Knutsen G, Drogset JO, Engebretsen L, Grøntvedt T, Ludvigsen TC, Løken S, Solheim E, Strand T, Johansen O (2016) A randomized multicenter trial comparing autologous chondrocyte implantation with microfracture: long-term follow-up at 14 to 15 years. J Bone Jt Surg Am 98:1332–1339CrossRef
14.
Zurück zum Zitat Kocher MS, Tucker R, Ganley TJ, Flynn JM (2006) Management of osteochondritis dissecans of the knee: current concepts review. Am J Sports Med 34:1181–1191CrossRefPubMed Kocher MS, Tucker R, Ganley TJ, Flynn JM (2006) Management of osteochondritis dissecans of the knee: current concepts review. Am J Sports Med 34:1181–1191CrossRefPubMed
15.
Zurück zum Zitat Kon E, Delcogliano M, Filardo G, Busacca M, Di Martino A, Marcacci M (2011) Novel nano-composite multilayered biomaterial for osteochondral regeneration: a pilot clinical trial. Am J Sports Med 39:1180–1190CrossRefPubMed Kon E, Delcogliano M, Filardo G, Busacca M, Di Martino A, Marcacci M (2011) Novel nano-composite multilayered biomaterial for osteochondral regeneration: a pilot clinical trial. Am J Sports Med 39:1180–1190CrossRefPubMed
16.
Zurück zum Zitat Kon E, Delcogliano M, Filardo G, Pressato D, Busacca M, Grigolo B, Desando G, Marcacci M (2010) A novel nano-composite multi-layered biomaterial for treatment of osteochondral lesions: technique note and an early stability pilot clinical trial. Injury 41:693–701CrossRefPubMed Kon E, Delcogliano M, Filardo G, Pressato D, Busacca M, Grigolo B, Desando G, Marcacci M (2010) A novel nano-composite multi-layered biomaterial for treatment of osteochondral lesions: technique note and an early stability pilot clinical trial. Injury 41:693–701CrossRefPubMed
17.
Zurück zum Zitat Lefort G, Moyen B, Beaufils P, de Billy B, Breda R, Cadilhac C, Clavert J-M, Djian P, Fenoll B, Giacomelli M-C, Gicquel P, Gicquel-Schlemmer B, Journeau P, Karger C, Laptoiu D, Lefort G, Mainard-Simard L, Moyen B, Negreanu I, Prové S, Robert H, Thaunat M, Versier G (2006) [Osteochondritis dissecans of the femoral condyles: report of 892 cases]. Rev Chir Orthop Reparatrice Appar Mot 92:2S97–92S141PubMed Lefort G, Moyen B, Beaufils P, de Billy B, Breda R, Cadilhac C, Clavert J-M, Djian P, Fenoll B, Giacomelli M-C, Gicquel P, Gicquel-Schlemmer B, Journeau P, Karger C, Laptoiu D, Lefort G, Mainard-Simard L, Moyen B, Negreanu I, Prové S, Robert H, Thaunat M, Versier G (2006) [Osteochondritis dissecans of the femoral condyles: report of 892 cases]. Rev Chir Orthop Reparatrice Appar Mot 92:2S97–92S141PubMed
18.
Zurück zum Zitat Lintz F, Pujol N, Pandeirada C, Boisrenoult P, Beaufils P (2011) Hybrid fixation: evaluation of a novel technique in adult osteochondritis dissecans of the knee. Knee Surg Sports Traumatol Arthrosc 19:568–571CrossRefPubMed Lintz F, Pujol N, Pandeirada C, Boisrenoult P, Beaufils P (2011) Hybrid fixation: evaluation of a novel technique in adult osteochondritis dissecans of the knee. Knee Surg Sports Traumatol Arthrosc 19:568–571CrossRefPubMed
19.
Zurück zum Zitat Martincic D, Radosavljevic D, Drobnic M (2014) Ten-year clinical and radiographic outcomes after autologous chondrocyte implantation of femoral condyles. Knee Surg Sports Traumatol Arthrosc 22:1277–1283CrossRefPubMed Martincic D, Radosavljevic D, Drobnic M (2014) Ten-year clinical and radiographic outcomes after autologous chondrocyte implantation of femoral condyles. Knee Surg Sports Traumatol Arthrosc 22:1277–1283CrossRefPubMed
20.
Zurück zum Zitat Mathis DT, Kaelin R, Rasch H, Arnold MP, Hirschmann MT (2017) Good clinical results but moderate osseointegration and defect filling of a cell-free multi-layered nano-composite scaffold for treatment of osteochondral lesions of the knee. Knee Surg Sports Traumatol Arthrosc 26:1273–1280PubMed Mathis DT, Kaelin R, Rasch H, Arnold MP, Hirschmann MT (2017) Good clinical results but moderate osseointegration and defect filling of a cell-free multi-layered nano-composite scaffold for treatment of osteochondral lesions of the knee. Knee Surg Sports Traumatol Arthrosc 26:1273–1280PubMed
21.
Zurück zum Zitat Miura K, Ishibashi Y, Tsuda E, Sato H, Toh S (2007) Results of arthroscopic fixation of osteochondritis dissecans lesion of the knee with cylindrical autogenous osteochondral plugs. Am J Sports Med 35:216–222CrossRefPubMed Miura K, Ishibashi Y, Tsuda E, Sato H, Toh S (2007) Results of arthroscopic fixation of osteochondritis dissecans lesion of the knee with cylindrical autogenous osteochondral plugs. Am J Sports Med 35:216–222CrossRefPubMed
22.
Zurück zum Zitat Murray JRD, Chitnavis J, Dixon P, Hogan NA, Parker G, Parish EN, Cross MJ (2007) Osteochondritis dissecans of the knee; long-term clinical outcome following arthroscopic debridement. Knee 14:94–98CrossRefPubMed Murray JRD, Chitnavis J, Dixon P, Hogan NA, Parker G, Parish EN, Cross MJ (2007) Osteochondritis dissecans of the knee; long-term clinical outcome following arthroscopic debridement. Knee 14:94–98CrossRefPubMed
23.
Zurück zum Zitat Navarro R, Cohen M, Filho MC, da Silva RT (2002) The arthroscopic treatment of osteochondritis dissecans of the knee with autologous bone sticks. Arthroscopy 18:840–844CrossRefPubMed Navarro R, Cohen M, Filho MC, da Silva RT (2002) The arthroscopic treatment of osteochondritis dissecans of the knee with autologous bone sticks. Arthroscopy 18:840–844CrossRefPubMed
24.
Zurück zum Zitat Roos EM, Roos HP, Lohmander LS, Ekdahl C, Beynnon BD (1998) Knee Injury and Osteoarthritis Outcome Score (KOOS)--development of a self-administered outcome measure. J Orthop Sports Phys Ther 28:88–96CrossRefPubMed Roos EM, Roos HP, Lohmander LS, Ekdahl C, Beynnon BD (1998) Knee Injury and Osteoarthritis Outcome Score (KOOS)--development of a self-administered outcome measure. J Orthop Sports Phys Ther 28:88–96CrossRefPubMed
25.
Zurück zum Zitat Rossi MJ, Lubowitz JH, Guttmann D (2002) Development and validation of the international knee documentation committee subjective knee form. Am J Sports Med 30:152CrossRefPubMed Rossi MJ, Lubowitz JH, Guttmann D (2002) Development and validation of the international knee documentation committee subjective knee form. Am J Sports Med 30:152CrossRefPubMed
26.
Zurück zum Zitat Sanders TL, Pareek A, Obey MR, Johnson NR, Carey JL, Stuart MJ, Krych AJ (2017) high rate of osteoarthritis after osteochondritis dissecans fragment excision compared with surgical restoration at a mean 16-year follow-up. Am J Sports Med 45:1799–1805CrossRefPubMed Sanders TL, Pareek A, Obey MR, Johnson NR, Carey JL, Stuart MJ, Krych AJ (2017) high rate of osteoarthritis after osteochondritis dissecans fragment excision compared with surgical restoration at a mean 16-year follow-up. Am J Sports Med 45:1799–1805CrossRefPubMed
27.
Zurück zum Zitat Selmi TS, Verdonk P, Chambat P, Dubrana F, Potel J-F, Barnouin L, Neyret P (2008) Autologous chondrocyte implantation in a novel alginate-agarose hydrogel: outcome at two years. J Bone Jt Surg Br 90:597–604CrossRef Selmi TS, Verdonk P, Chambat P, Dubrana F, Potel J-F, Barnouin L, Neyret P (2008) Autologous chondrocyte implantation in a novel alginate-agarose hydrogel: outcome at two years. J Bone Jt Surg Br 90:597–604CrossRef
28.
Zurück zum Zitat Slough JA, Noto AM, Schmidt TL (1991) Tibial cortical bone peg fixation in osteochondritis dissecans of the knee. Clin Orthop Relat Res 267:122–127 Slough JA, Noto AM, Schmidt TL (1991) Tibial cortical bone peg fixation in osteochondritis dissecans of the knee. Clin Orthop Relat Res 267:122–127
29.
Zurück zum Zitat Tampieri A, Sandri M, Landi E, Pressato D, Francioli S, Quarto R, Martin I (2008) Design of graded biomimetic osteochondral composite scaffolds. Biomaterials 29:3539–3546CrossRefPubMed Tampieri A, Sandri M, Landi E, Pressato D, Francioli S, Quarto R, Martin I (2008) Design of graded biomimetic osteochondral composite scaffolds. Biomaterials 29:3539–3546CrossRefPubMed
30.
Zurück zum Zitat Verdonk P, Dhollander A, Almqvist KF, Verdonk R, Victor J (2015) Treatment of osteochondral lesions in the knee using a cell-free scaffold. Bone Jt J 97-B:318–323CrossRef Verdonk P, Dhollander A, Almqvist KF, Verdonk R, Victor J (2015) Treatment of osteochondral lesions in the knee using a cell-free scaffold. Bone Jt J 97-B:318–323CrossRef
31.
Zurück zum Zitat Wright RW, McLean M, Matava MJ, Shively RA (2004) Osteochondritis dissecans of the knee: long-term results of excision of the fragment. Clin Orthop Relat Res 424:239–243CrossRef Wright RW, McLean M, Matava MJ, Shively RA (2004) Osteochondritis dissecans of the knee: long-term results of excision of the fragment. Clin Orthop Relat Res 424:239–243CrossRef
Metadaten
Titel
Neither significant osteoarthritic changes nor deteriorating subjective outcomes occur after hybrid fixation of osteochondritis dissecans in the young adult
verfasst von
L. Chadli
C. Steltzlen
P. Beaufils
C. Toanen
N. Pujol
Publikationsdatum
19.06.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
Knee Surgery, Sports Traumatology, Arthroscopy / Ausgabe 3/2019
Print ISSN: 0942-2056
Elektronische ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-018-5025-0

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