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Irish Journal of Medical Science (1971 -)

Erschienen in:

03.01.2017 | Original Article

Nitrate-rich beetroot juice selectively lowers ambulatory pressures and LDL cholesterol in uncontrolled but not controlled hypertension: a pilot study

verfasst von: C. P. Kerley, E. Dolan, L. Cormican

Erschienen in: Irish Journal of Medical Science (1971 -) | Ausgabe 4/2017

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Abstract

Background

Dietary nitrate has been shown to increase nitrate/nitrite levels in multiple populations, with potential blood pressure lowering effects. However, there are few reports among hypertensives.

Aims

We aimed to assess the effect of daily nitrate in subjects with controlled hypertension vs. uncontrolled hypertension.

Methods

On day 0, hypertensives wore an ambulatory BP monitor (ABPM) for 24 h and fasting blood was taken. Subjects then consumed concentrated beetroot juice (12.9 mmol nitrate) for 14 consecutive days. On day 14 subjects consumed their last nitrate dose after fasting blood was drawn and again had an ABPM for 24 h.

Results

According to baseline ABPM, 11 subjects had controlled BP while 8 had uncontrolled BP. There were similar, significant increases in serum nitrate/nitrite in both groups. We observed little change in BP variables among controlled hypertensives. However, there were reductions in BP variables in uncontrolled hypertensives where decreases in nighttime DBP (−6 ± 4.8 mmHg), arterial stiffness (−0.08 ± 0.03 ambulatory arterial stiffness index) and LDL (−0.36 ± 0.42 mmol/L) reached significance (p = 003, 0.05 and 0.046, respectively).

Conclusions

Our results support the existing data suggesting an anti-hypertensive effect of nitrate-containing beetroot juice, but only among those with uncontrolled hypertension.

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Titel: Nitrate-rich beetroot juice selectively lowers ambulatory pressures and LDL cholesterol in uncontrolled but not controlled hypertension: a pilot study
verfasst von: C. P. Kerley
E. Dolan
L. Cormican
Publikationsdatum: 03.01.2017
Verlag: Springer London
Erschienen in: Irish Journal of Medical Science (1971 -) / Ausgabe 4/2017
Print ISSN: 0021-1265
Elektronische ISSN: 1863-4362
DOI: https://doi.org/10.1007/s11845-016-1551-2

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Springer Medizin

Nitrate-rich beetroot juice selectively lowers ambulatory pressures and LDL cholesterol in uncontrolled but not controlled hypertension: a pilot study

Abstract

Background

Aims

Methods

Results

Conclusions

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Die „Zehn Gebote“ des Endokarditis-Managements

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Abstract

Background

Aims

Methods

Results

Conclusions

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