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01.12.2012 | Research | Ausgabe 1/2012 Open Access

Cardiovascular Ultrasound 1/2012

No relationship between left ventricular radial wall motion and longitudinal velocity and the extent and severity of noncompaction cardiomyopathy

Zeitschrift:
Cardiovascular Ultrasound > Ausgabe 1/2012
Autoren:
Kadir Caliskan, Osama I Soliman, Attila Nemes, Ron T van Domburg, Maarten L Simoons, Marcel L Geleijnse
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1476-7120-10-9) contains supplementary material, which is available to authorized users.

Competing interests

The authors declare that they have no competing interests.

Abstract

Background

Noncompaction cardiomyopathy (NCCM) is characterized by a prominent trabecular meshwork and deep intertrabecular recesses. Although systolic dysfunction is common, limited information is available on differences in wall motion of the normal compacted and noncompacted segments. The purpose of this study was to assess radial wall motion and longitudinal wall velocity in patients with NCCM, according to the extent and severity of noncompaction.

Methods

The study comprised 29 patients in sinus rhythm (age 41 ± 15 years, 15 men), who fulfilled stringent diagnostic criteria for NCCM and compared to 29 age and gender matched healthy controls. Segmental radial wall motion of all compacted and noncompacted segments was assessed with the standard visual wall motion score index and longitudinal systolic (Sm) wall velocity with tissue Doppler imaging of the mitral annulus. For each LV wall a normalized Sm value was calculated. The extent and severity of NC in each LV segment was assessed both in a qualitative and quantitative manner.

Results

Heart failure was the primary clinical presentation in half of the patients. NCCM patients had a wall motion score index of 1.68 ± 0.43 and a normalized Sm of 82 ± 20%. The total and maximal noncompaction scores were not related to the wall motion score index and the normalized Sm. NCCM patients with and without heart failure had similar total and maximal noncompaction scores.

Conclusions

In NCCM patient's radial wall motion and longitudinal LV wall velocity is impaired but not related to the extent or severity of noncompaction.
Zusatzmaterial
Additional file 1: Movie 1 A Apical four chamber and parasternal short axis view of a 37 years old male presenting with severe heart failure en left bundle branch block. Familial screening revealed several affected first degree relatives. Echocardiographically, there are prominent trabeculations with noncomapcted/compacted ratio > 2 at the parasternal short axis view in end systole. There is not only visual LV dyssynchrony, but also diffuse wall motion abnormalities which are not only confined to the noncompacted segments. The systolic wall velocity with tissue Doppler imaging of the mitral annulus was respectively 4.8 cm/s (age/gender matched healthy control: 9.13 cm/s) and 6.3 cm/s (control: 9.4 cm/s) in septal wall and lateral wall. (AVI 3 MB)
12947_2011_412_MOESM1_ESM.avi
Additional file 2: Movie 1 B Apical four chamber and parasternal short axis view of a 37 years old male presenting with severe heart failure en left bundle branch block. Familial screening revealed several affected first degree relatives. Echocardiographically, there are prominent trabeculations with noncomapcted/compacted ratio > 2 at the parasternal short axis view in end systole. There is not only visual LV dyssynchrony, but also diffuse wall motion abnormalities which are not only confined to the noncompacted segments. The systolic wall velocity with tissue Doppler imaging of the mitral annulus was respectively 4.8 cm/s (age/gender matched healthy control: 9.13 cm/s) and 6.3 cm/s (control: 9.4 cm/s) in septal wall and lateral wall. (AVI 2 MB)
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Authors’ original file for figure 1
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Authors’ original file for figure 2
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Authors’ original file for figure 3
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Authors’ original file for figure 4
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