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01.12.2012 | Research | Ausgabe 1/2012 Open Access

Cardiovascular Ultrasound 1/2012

Midwall ejection fraction for assessing systolic performance of the hypertrophic left ventricle

Zeitschrift:
Cardiovascular Ultrasound > Ausgabe 1/2012
Autoren:
Hisao Yoshikawa, Makoto Suzuki, Go Hashimoto, Yukiko Kusunose, Takenori Otsuka, Masato Nakamura, Kaoru Sugi
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1476-7120-10-45) contains supplementary material, which is available to authorized users.

Competing interests

The authors have no competing interests.

Authors’ contributions

HY, MS, and GH planned the study, investigated all patients, performed measurements and analyzed the data. YK and TO analyzed data and wrote the manuscript. MN and KS made critical review of the paper. All authors read and approved the final manuscript.

Abstract

Background

In patients with left ventricular hypertrophy (LVH), LV midwall fractional shortening (FS) is used as a measure of LV systolic performance that is more physiologically appropriate than conventional FS. For evaluation of LV volume and ejection fraction (EF), 2-dimensional (2D) echocardiography is more accurate than M-mode echocardiography. The purpose of this study was to assess systolic performance by midwall EF using 2D speckle tracking echocardiography (STE).

Methods

Sixty patients were enrolled in the study. Patients were divided into two groups with LVH (n = 30) and without LVH (control group, n = 30). LV systolic function was compared between the two groups and the relationships of left ventricular mass index (LVMI) with LV systolic parameters, including midwall EF, were investigated.

Results

Midwall EF in the LVH group was significantly lower than that in the control group (42.8±4.4% vs. 48.1±4.1%, p <0.0001). Midwall FS was also significantly lower in the LVH group (13.4±2.8% vs. 16.1±1.5%, p <0.0001), but EF did not differ significantly between the two groups. There were significant correlations between midwall EF and LVMI (r=0.731, p <0.0001) and between midwall FS and LVMI (r=0.693, p <0.0001), with midwall EF having the higher correlation.

Conclusions

These results show that midwall EF can be determined using 2D STE. Midwall EF can be used to monitor LV systolic dysfunction, which is not possible with conventional EF. Evaluation of midwall EF may allow assessment of new parameters of LV systolic function in patients with LV geometric variability.
Zusatzmaterial
Authors’ original file for figure 1
12947_2012_449_MOESM1_ESM.tiff
Authors’ original file for figure 2
12947_2012_449_MOESM2_ESM.tiff
Literatur
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