Renal prognosis in living kidney donors with diabetes is currently not known. In this study, we sought to investigate renal prognosis in living kidney donors with diabetes.
We retrospectively investigated 241 living kidney donors who underwent nephrectomy at Jichi Medical University Hospital between January 2000 and December 2015. Donors with a follow-up period of less than 1 year were excluded. The remaining donors were divided into a diabetic group and a non-diabetic group. Their clinical parameters before donation and renal prognosis after donation were compared.
Of the 241 donors, 16 were excluded due to their follow-up period being less than 1 year. Of the remaining 225 donors, 14 were diabetic and 211 were non-diabetic. There were no significant differences in variables at pre-donation. The median follow-up period was 4.3 (1.5–10.7) and 4.6 (1.0–13.0) years in kidney donors with and without diabetes, respectively. At the end of follow-up, the estimated glomerular filtration rate was 51.7 ± 7.1 ml/min/1.73 m2 in the diabetic group and 52.1 ± 12.2 ml/min/1.73 m2 (p = 0.906) in the non-diabetic group; urine albumin excretion was 9.5 (2–251) mg/day (or mg/g creatinine) in the diabetic group and 6 (0–626) mg/day (or mg/g creatinine) in the non-diabetic group (p = 0.130); and urine protein excretion was 0.079 (0–0.41) g/day in the diabetic group and 0.051 (0–3.7) g/day in the non-diabetic group (p = 0.455).
There were no significant differences in short-term renal prognosis between kidney donors with and without diabetes.
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- No significant differences in short-term renal prognosis between living kidney donors with and without diabetes
- Springer Singapore
Clinical and Experimental Nephrology
Official Publication of the Japanese Society of Nephrology
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