Skip to main content
Erschienen in: Herz 6/2021

09.11.2021 | Main topic

Non-transvenous ICD therapy: current status and beyond

verfasst von: Vincent F. van Dijk, MD PhD, Lucas V. A. Boersma, MD PhD

Erschienen in: Herz | Ausgabe 6/2021

Einloggen, um Zugang zu erhalten

Abstract

Subcutaneous implantable cardioverter/defibrillators (S-ICDs) have been developed to offer ICD treatment to patients without venous access to the heart and to overcome complications associated with transvenous leads, particularly lead fracture/insulation defects and endocarditis. Several studies and registries have demonstrated the feasibility and safety of S‑ICD in different groups of patients. Further developments in S‑ICD technology involve the combination with devices that can provide anti-bradycardia and anti-tachycardia pacing if needed. The extravascular ICD (EV-ICD) is a new system that similarly offers ICD therapy without a transvenous lead but uses a substernal instead of a subcutaneous lead to facilitate detection of ventricular fibrillation and to provide anti-tachycardia and also temporary anti-bradycardia pacing. The first animal but also clinical data on EV-ICDs have been published. This review discusses the current state, potential advantages and limitations, and future research of both S‑ICD and EV-ICD.
Literatur
1.
Zurück zum Zitat Connolly SJ, Hallstrom AP, Cappato R et al (2000) meta-analysis of the implantable cardioverter defibrillator secondary prevention trials. AVID, CASH and CIDS studies. Antiarrhythmics vs implantable defibrillator study. Cardiac arrest study hamburg. Canadian implantable defibrillator study. Eur Heart J 21(24):2071–2078CrossRef Connolly SJ, Hallstrom AP, Cappato R et al (2000) meta-analysis of the implantable cardioverter defibrillator secondary prevention trials. AVID, CASH and CIDS studies. Antiarrhythmics vs implantable defibrillator study. Cardiac arrest study hamburg. Canadian implantable defibrillator study. Eur Heart J 21(24):2071–2078CrossRef
2.
Zurück zum Zitat Moss AJ, Zareba W, Hall WJ et al (2002) Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N Engl J Med 346(12):877–883CrossRef Moss AJ, Zareba W, Hall WJ et al (2002) Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N Engl J Med 346(12):877–883CrossRef
3.
Zurück zum Zitat Priori SG, Blomstrom-Lundqvist C, Mazzanti A et al (2015) 2015 ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: the task force for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death of the europe. Eur Heart J 36(41):2793–2867CrossRef Priori SG, Blomstrom-Lundqvist C, Mazzanti A et al (2015) 2015 ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: the task force for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death of the europe. Eur Heart J 36(41):2793–2867CrossRef
4.
Zurück zum Zitat Al-Khatib SM, Stevenson WG, Ackerman MJ et al (2018) 2017 AHA/ACC/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American college of cardiology/American heart association task force on clinical practice guidelines and the heart rhythm society. Heart Rhythm 15(10):e73–189CrossRef Al-Khatib SM, Stevenson WG, Ackerman MJ et al (2018) 2017 AHA/ACC/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American college of cardiology/American heart association task force on clinical practice guidelines and the heart rhythm society. Heart Rhythm 15(10):e73–189CrossRef
5.
Zurück zum Zitat Maisel WH, Moynahan M, Zuckerman BD et al (2006) Pacemaker and ICD generator malfunctions: analysis of food and drug administration annual reports. JAMA 295(16):1901–1906CrossRef Maisel WH, Moynahan M, Zuckerman BD et al (2006) Pacemaker and ICD generator malfunctions: analysis of food and drug administration annual reports. JAMA 295(16):1901–1906CrossRef
6.
Zurück zum Zitat Habib A, Le KY, Baddour LM et al (2013) Predictors of mortality in patients with cardiovascular implantable electronic device infections. Am J Cardiol 111(6):874–879CrossRef Habib A, Le KY, Baddour LM et al (2013) Predictors of mortality in patients with cardiovascular implantable electronic device infections. Am J Cardiol 111(6):874–879CrossRef
7.
Zurück zum Zitat Bardy GH, Smith WM, Hood MA et al (2010) An entirely subcutaneous implantable cardioverter-defibrillator. N Engl J Med 363(1):36–44CrossRef Bardy GH, Smith WM, Hood MA et al (2010) An entirely subcutaneous implantable cardioverter-defibrillator. N Engl J Med 363(1):36–44CrossRef
9.
Zurück zum Zitat McLeod CJ, Boersma L, Okamura H, Friedman PA (2017) The subcutaneous implantable cardioverter defibrillator: state-of-the-art review. Eur Heart J 38(4):247–257CrossRef McLeod CJ, Boersma L, Okamura H, Friedman PA (2017) The subcutaneous implantable cardioverter defibrillator: state-of-the-art review. Eur Heart J 38(4):247–257CrossRef
10.
Zurück zum Zitat Boersma LV, Barr CS, Burke MC et al (2017) Performance of the subcutaneous implantable cardioverter-defibrillator in patients with a primary prevention indication with and without a reduced ejection fraction versus patients with a secondary prevention indication. Heart Rhythm 14(3):367–375CrossRef Boersma LV, Barr CS, Burke MC et al (2017) Performance of the subcutaneous implantable cardioverter-defibrillator in patients with a primary prevention indication with and without a reduced ejection fraction versus patients with a secondary prevention indication. Heart Rhythm 14(3):367–375CrossRef
11.
Zurück zum Zitat Weiss R, Knight BP, Gold MR et al (2013) Safety and efficacy of a totally subcutaneous implantable-cardioverter defibrillator. Circulation 128(9):944–953CrossRef Weiss R, Knight BP, Gold MR et al (2013) Safety and efficacy of a totally subcutaneous implantable-cardioverter defibrillator. Circulation 128(9):944–953CrossRef
12.
Zurück zum Zitat Quast ABE, van Dijk VF, Yap SC et al (2018) Six-year follow-up of the initial Dutch subcutaneous implantable cardioverter-defibrillator cohort: long-term complications, replacements, and battery longevity. J Cardiovasc Electrophysiol 29(7):1010–1016. https://doi.org/10.1111/jce.13498CrossRefPubMed Quast ABE, van Dijk VF, Yap SC et al (2018) Six-year follow-up of the initial Dutch subcutaneous implantable cardioverter-defibrillator cohort: long-term complications, replacements, and battery longevity. J Cardiovasc Electrophysiol 29(7):1010–1016. https://​doi.​org/​10.​1111/​jce.​13498CrossRefPubMed
13.
Zurück zum Zitat Burke MC, Aasbo JD, El-Chami MF et al (2020) 1‑year prospective evaluation of clinical outcomes and shocks: the subcutaneous ICD post approval study. JACC Clin Electrophysiol 6(12):1537–1550CrossRef Burke MC, Aasbo JD, El-Chami MF et al (2020) 1‑year prospective evaluation of clinical outcomes and shocks: the subcutaneous ICD post approval study. JACC Clin Electrophysiol 6(12):1537–1550CrossRef
14.
Zurück zum Zitat Gold MR, Lambiase PD, El-Chami MF et al (2021) Primary results from the understanding outcomes with the S‑ICD in primary prevention patients with low ejection fraction (UNTOUCHED) trial. Circulation 143(1):7–17CrossRef Gold MR, Lambiase PD, El-Chami MF et al (2021) Primary results from the understanding outcomes with the S‑ICD in primary prevention patients with low ejection fraction (UNTOUCHED) trial. Circulation 143(1):7–17CrossRef
15.
Zurück zum Zitat Knops RE, Olde Nordkamp LRA, Delnoy P‑PHM et al (2020) Subcutaneous or transvenous defibrillator therapy. N Engl J Med 383(6):526–536CrossRef Knops RE, Olde Nordkamp LRA, Delnoy P‑PHM et al (2020) Subcutaneous or transvenous defibrillator therapy. N Engl J Med 383(6):526–536CrossRef
16.
Zurück zum Zitat Brisben AJ, Burke MC, Knight BP et al (2015) A new algorithm to reduce inappropriate therapy in the S‑ICD system. J Cardiovasc Electrophysiol 26(4):417–423CrossRef Brisben AJ, Burke MC, Knight BP et al (2015) A new algorithm to reduce inappropriate therapy in the S‑ICD system. J Cardiovasc Electrophysiol 26(4):417–423CrossRef
17.
Zurück zum Zitat Theuns DAMJ, Brouwer TF, Jones PW et al (2018) Prospective blinded evaluation of a novel sensing methodology designed to reduce inappropriate shocks by the subcutaneous implantable cardioverter-defibrillator. Heart Rhythm 15(10):1515–1522CrossRef Theuns DAMJ, Brouwer TF, Jones PW et al (2018) Prospective blinded evaluation of a novel sensing methodology designed to reduce inappropriate shocks by the subcutaneous implantable cardioverter-defibrillator. Heart Rhythm 15(10):1515–1522CrossRef
18.
Zurück zum Zitat Moss AJ, Schuger C, Beck CA et al (2012) Reduction in inappropriate therapy and mortality through ICD programming. N Engl J Med 367(24):2275–2283CrossRef Moss AJ, Schuger C, Beck CA et al (2012) Reduction in inappropriate therapy and mortality through ICD programming. N Engl J Med 367(24):2275–2283CrossRef
19.
Zurück zum Zitat Wilkoff BL, Fauchier L, Stiles MK et al (2016) 2015 HRS/EHRA/APHRS/SOLAECE expert consensus statement on optimal implantable cardioverter-defibrillator programming and testing. J Arrhythmia 32(1):1–28CrossRef Wilkoff BL, Fauchier L, Stiles MK et al (2016) 2015 HRS/EHRA/APHRS/SOLAECE expert consensus statement on optimal implantable cardioverter-defibrillator programming and testing. J Arrhythmia 32(1):1–28CrossRef
20.
Zurück zum Zitat Quast A‑FBE, Baalman SWE, Brouwer TF et al (2019) A novel tool to evaluate the implant position and predict defibrillation success of the subcutaneous implantable cardioverter-defibrillator: the PRAETORIAN score. Heart Rhythm 16(3):403–410CrossRef Quast A‑FBE, Baalman SWE, Brouwer TF et al (2019) A novel tool to evaluate the implant position and predict defibrillation success of the subcutaneous implantable cardioverter-defibrillator: the PRAETORIAN score. Heart Rhythm 16(3):403–410CrossRef
21.
Zurück zum Zitat Quast A‑FBE, Baalman SWE, Betts TR et al (2019) Rationale and design of the PRAETORIAN-DFT trial: a prospective randomized CompArative trial of SubcutanEous ImplanTable CardiOverter-DefibrillatoR ImplANtation with and without DeFibrillation testing. Am Heart J 214:167–174CrossRef Quast A‑FBE, Baalman SWE, Betts TR et al (2019) Rationale and design of the PRAETORIAN-DFT trial: a prospective randomized CompArative trial of SubcutanEous ImplanTable CardiOverter-DefibrillatoR ImplANtation with and without DeFibrillation testing. Am Heart J 214:167–174CrossRef
22.
Zurück zum Zitat Tjong FVY, Brouwer TF, Kooiman KM et al (2016) Communicating antitachycardia pacing-enabled leadless pacemaker and subcutaneous implantable defibrillator. J Am Coll Cardiol 67:1865–1866CrossRef Tjong FVY, Brouwer TF, Kooiman KM et al (2016) Communicating antitachycardia pacing-enabled leadless pacemaker and subcutaneous implantable defibrillator. J Am Coll Cardiol 67:1865–1866CrossRef
23.
Zurück zum Zitat Quast A‑FBE, Tjong FVY, Koop BE et al (2018) Device orientation of a leadless pacemaker and subcutaneous implantable cardioverter-defibrillator in canine and human subjects and the effect on intrabody communication. Europace 20(11):1866–1871CrossRef Quast A‑FBE, Tjong FVY, Koop BE et al (2018) Device orientation of a leadless pacemaker and subcutaneous implantable cardioverter-defibrillator in canine and human subjects and the effect on intrabody communication. Europace 20(11):1866–1871CrossRef
24.
Zurück zum Zitat Tjong FVY, Brouwer TF, Koop B et al (2017) Acute and 3‑month performance of a communicating leadless antitachycardia pacemaker and subcutaneous implantable defibrillator. JACC Clin Electrophysiol 3(13):1487–1498CrossRef Tjong FVY, Brouwer TF, Koop B et al (2017) Acute and 3‑month performance of a communicating leadless antitachycardia pacemaker and subcutaneous implantable defibrillator. JACC Clin Electrophysiol 3(13):1487–1498CrossRef
25.
Zurück zum Zitat Mondesert B, Dubuc M, Khairy P et al (2015) Combination of a leadless pacemaker and subcutaneous defibrillator: first in-human report. HeartRhythm Case Rep 1(6):469–471CrossRef Mondesert B, Dubuc M, Khairy P et al (2015) Combination of a leadless pacemaker and subcutaneous defibrillator: first in-human report. HeartRhythm Case Rep 1(6):469–471CrossRef
26.
Zurück zum Zitat Botto GL, Forleo GB, Capucci A et al (2017) The Italian subcutaneous implantable cardioverter-defibrillator survey: S‑ICD, why not? Europace 19(11):1826–1832CrossRef Botto GL, Forleo GB, Capucci A et al (2017) The Italian subcutaneous implantable cardioverter-defibrillator survey: S‑ICD, why not? Europace 19(11):1826–1832CrossRef
27.
Zurück zum Zitat Tung SK, Bennett M, Yeung-Lai-Wah JALH (2007) Minimal invasive extra cardiac placement of high voltage defibrillator leads. Heart Rhythm 4(5):S200 Tung SK, Bennett M, Yeung-Lai-Wah JALH (2007) Minimal invasive extra cardiac placement of high voltage defibrillator leads. Heart Rhythm 4(5):S200
28.
Zurück zum Zitat Bhagwandien RE, Kik C, Yap S‑C, Szili-Torok T (2016) Substernal ICD lead implantation in a patient not suitable for subcutaneous ICD implantation without venous access due to superior vena cava syndrome. HeartRhythm Case Rep 3(1):97–99CrossRef Bhagwandien RE, Kik C, Yap S‑C, Szili-Torok T (2016) Substernal ICD lead implantation in a patient not suitable for subcutaneous ICD implantation without venous access due to superior vena cava syndrome. HeartRhythm Case Rep 3(1):97–99CrossRef
29.
Zurück zum Zitat Sholevar DP, Tung S, Kuriachan V et al (2018) Feasibility of extravascular pacing with a novel substernal electrode configuration: the substernal pacing acute clinical evaluation study. Heart Rhythm 15(4):536–542CrossRef Sholevar DP, Tung S, Kuriachan V et al (2018) Feasibility of extravascular pacing with a novel substernal electrode configuration: the substernal pacing acute clinical evaluation study. Heart Rhythm 15(4):536–542CrossRef
30.
Zurück zum Zitat Chan JYS, Lelakowski J, Murgatroyd FD et al (2017) Novel extravascular defibrillation configuration with a coil in the substernal space: the ASD clinical study. JACC Clin Electrophysiol 3(8):905–910CrossRef Chan JYS, Lelakowski J, Murgatroyd FD et al (2017) Novel extravascular defibrillation configuration with a coil in the substernal space: the ASD clinical study. JACC Clin Electrophysiol 3(8):905–910CrossRef
31.
Zurück zum Zitat Boersma LVA, Merkely B, Neuzil P et al (2019) Therapy from a novel substernal lead: the ASD2 study. JACC Clin Electrophysiol 5(2):186–196CrossRef Boersma LVA, Merkely B, Neuzil P et al (2019) Therapy from a novel substernal lead: the ASD2 study. JACC Clin Electrophysiol 5(2):186–196CrossRef
32.
Zurück zum Zitat Crozier I, Haqqani H, Kotschet E et al (2020) First-in-human chronic implant experience of the substernal extravascular implantable cardioverter-defibrillator. JACC Clin Electrophysiol 6(12):1525–1536CrossRef Crozier I, Haqqani H, Kotschet E et al (2020) First-in-human chronic implant experience of the substernal extravascular implantable cardioverter-defibrillator. JACC Clin Electrophysiol 6(12):1525–1536CrossRef
33.
Zurück zum Zitat Boersma L, Barr C, Knops R et al (2017) Implant and midterm outcomes of the subcutaneous implantable cardioverter-defibrillator registry: the EFFORTLESS study. J Am Coll Cardiol 70(7):830–841CrossRef Boersma L, Barr C, Knops R et al (2017) Implant and midterm outcomes of the subcutaneous implantable cardioverter-defibrillator registry: the EFFORTLESS study. J Am Coll Cardiol 70(7):830–841CrossRef
Metadaten
Titel
Non-transvenous ICD therapy: current status and beyond
verfasst von
Vincent F. van Dijk, MD PhD
Lucas V. A. Boersma, MD PhD
Publikationsdatum
09.11.2021
Verlag
Springer Medizin
Erschienen in
Herz / Ausgabe 6/2021
Print ISSN: 0340-9937
Elektronische ISSN: 1615-6692
DOI
https://doi.org/10.1007/s00059-021-05077-4

Weitere Artikel der Ausgabe 6/2021

Herz 6/2021 Zur Ausgabe

Das Risiko für Vorhofflimmern in der Bevölkerung steigt

02.05.2024 Vorhofflimmern Nachrichten

Das Risiko, im Lauf des Lebens an Vorhofflimmern zu erkranken, ist in den vergangenen 20 Jahren gestiegen: Laut dänischen Zahlen wird es drei von zehn Personen treffen. Das hat Folgen weit über die Schlaganfallgefährdung hinaus.

VHF-Ablation nützt wohl nur bei reduzierter Auswurfleistung

02.05.2024 Ablationstherapie Nachrichten

Ob die Katheterablation von Vorhofflimmern bei Patienten mit Herzinsuffizienz die Komplikationsraten senkt, scheint davon abzuhängen, ob die Auswurfleistung erhalten ist oder nicht. Das legen die Ergebnisse einer Metaanalyse nahe.

Weniger Extremitätenischämien mit dualer Plättchenhemmung

02.05.2024 Thrombozytenaggregationshemmer Nachrichten

Eine Behandlung mit Ticagrelor zusätzlich zu ASS kann das Risiko für Revaskularisierungen und Amputationen von Extremitäten bei Diabetikern mit stabiler KHK deutlich reduzieren, vor allem für solche mit PAVK. Dafür spricht eine Auswertung der Interventionsstudie THEMIS.

Endlich: Zi zeigt, mit welchen PVS Praxen zufrieden sind

IT für Ärzte Nachrichten

Darauf haben viele Praxen gewartet: Das Zi hat eine Liste von Praxisverwaltungssystemen veröffentlicht, die von Nutzern positiv bewertet werden. Eine gute Grundlage für wechselwillige Ärzte und Psychotherapeuten.

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.