Skip to main content
Erschienen in: Neuroradiology 9/2013

01.09.2013 | Interventional Neuroradiology

Novel 3D-CT evaluation of carotid stent volume: greater chronological expansion of stents in patients with vulnerable plaques

verfasst von: Hisakazu Itami, Koji Tokunaga, Yu Okuma, Tomohito Hishikawa, Kenji Sugiu, Kentaro Ida, Isao Date

Erschienen in: Neuroradiology | Ausgabe 9/2013

Einloggen, um Zugang zu erhalten

Abstract

Introduction

Although self-expanding carotid stents may dilate gradually, the degrees of residual stenosis have been quantified by the NASCET criteria, which is too simple to reflect the configuration of the stented artery. We measured the volumes of the stent lumens chronologically by 3D-CT in patients after carotid artery stenting (CAS), and analyzed the correlations between the volume change and medical factors.

Methods

Fourteen patients with carotid artery stenosis were treated using self-expanding, open-cell stents. All patients underwent preoperative plaque MRI (magnetization-prepared rapid acquisition gradient-echo, MPRAGE) and chronological 3D-CT examinations of their stents immediately after their placement and 1 day, 1 week, and 1 month after the procedure. The volume of the stent lumen was measured using a 3D workstation. The correlations between stent volume and various factors including the presence of underlying diseases, plaque characteristics, and the results of the CAS procedure were analyzed.

Results

Stent volume gradually increased in each case and had increased by 1.04–1.55 (mean, 1.25)-fold at 1 postoperative month. The presence of underlying medical diseases, plaque length, the degree of residual stenosis immediately after CAS, and plaque calcification did not have an impact on the change in stent volume. On the other hand, the stent volume increase was significantly larger in the patients with vulnerable plaques that demonstrated high MPRAGE signal intensity (P < 0.05).

Conclusions

A 3D-CT examination is useful for precisely measuring stent volume. Self-expanding stents in carotid arteries containing vulnerable plaques expand significantly more than those without such plaques in a follow-up period.
Literatur
1.
Zurück zum Zitat Men S, Lownie SP, Pelz DM (2002) Carotid stenting without angioplasty. Can J Neurol Sci 29:175–179PubMed Men S, Lownie SP, Pelz DM (2002) Carotid stenting without angioplasty. Can J Neurol Sci 29:175–179PubMed
2.
Zurück zum Zitat Roguin A, Grenadier E, Linn S, Markiewicz W, Beyar R (1999) Continued expansion of the nitinol self-expanding coronary stent: angiographic analysis and 1-year clinical follow-up. Am Heart J 138:326–333CrossRefPubMed Roguin A, Grenadier E, Linn S, Markiewicz W, Beyar R (1999) Continued expansion of the nitinol self-expanding coronary stent: angiographic analysis and 1-year clinical follow-up. Am Heart J 138:326–333CrossRefPubMed
3.
Zurück zum Zitat von Birgelen C, Airiian SG, de Feyter PJ, Foley DP, van der Giessen WJ, Serruys PW (1998) Coronary wallstents show significant late, postprocedural expansion despite implantation with adjunct high-pressure balloon inflations. Am J Cardiol 82:129–134CrossRef von Birgelen C, Airiian SG, de Feyter PJ, Foley DP, van der Giessen WJ, Serruys PW (1998) Coronary wallstents show significant late, postprocedural expansion despite implantation with adjunct high-pressure balloon inflations. Am J Cardiol 82:129–134CrossRef
4.
Zurück zum Zitat Lownie SP, Pelz DM, Lee DH, Men S, Gulka I, Kalapos P (2005) Efficacy of treatment of severe carotid bifurcation stenosis by using self-expanding stents without deliberate use of angioplasty balloons. AJNR Am J Neuroradiol 26:1241–1248PubMed Lownie SP, Pelz DM, Lee DH, Men S, Gulka I, Kalapos P (2005) Efficacy of treatment of severe carotid bifurcation stenosis by using self-expanding stents without deliberate use of angioplasty balloons. AJNR Am J Neuroradiol 26:1241–1248PubMed
5.
7.
Zurück zum Zitat Willfort-Ehringer A, Ahmadi R, Gruber D, Gschwandtner ME, Haumer A, Haumer M, Ehringer H (2004) Arterial remodeling and hemodynamics in carotid stents: a prospective duplex ultrasound study over 2 years. J Vasc Surg 39:728–734. doi:10.1016/j.jvs.2003.12.029 CrossRefPubMed Willfort-Ehringer A, Ahmadi R, Gruber D, Gschwandtner ME, Haumer A, Haumer M, Ehringer H (2004) Arterial remodeling and hemodynamics in carotid stents: a prospective duplex ultrasound study over 2 years. J Vasc Surg 39:728–734. doi:10.​1016/​j.​jvs.​2003.​12.​029 CrossRefPubMed
8.
Zurück zum Zitat Watarai H, Kaku Y, Yamada M, Kokuzawa J, Tanaka T, Andoh T, Iwama T (2009) Follow-up study on in-stent thrombosis after carotid stenting using multidetector CT angiography. Neuroradiology 51:243–251. doi:10.1007/s00234-009-0498-7 CrossRefPubMed Watarai H, Kaku Y, Yamada M, Kokuzawa J, Tanaka T, Andoh T, Iwama T (2009) Follow-up study on in-stent thrombosis after carotid stenting using multidetector CT angiography. Neuroradiology 51:243–251. doi:10.​1007/​s00234-009-0498-7 CrossRefPubMed
9.
Zurück zum Zitat North American Symptomatic Carotid Endarterectomy Trial Collaborators (1991) Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med 325:445–453. doi:10.1056/nejm199108153250701 CrossRef North American Symptomatic Carotid Endarterectomy Trial Collaborators (1991) Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med 325:445–453. doi:10.​1056/​nejm199108153250​701 CrossRef
10.
Zurück zum Zitat Tokunaga K, Sugiu K, Hayase H, Nishida A, Date I (2009) Significant differences in the postoperative morphological and hemodynamic conditions of carotid arteries of patients undergoing stenting or endarterectomy with patch angioplasty. Neurosurgery 65:884–888. doi:10.1227/01.NEU.0000358952.12917.DF, discussion 888-889CrossRefPubMed Tokunaga K, Sugiu K, Hayase H, Nishida A, Date I (2009) Significant differences in the postoperative morphological and hemodynamic conditions of carotid arteries of patients undergoing stenting or endarterectomy with patch angioplasty. Neurosurgery 65:884–888. doi:10.​1227/​01.​NEU.​0000358952.​12917.​DF, discussion 888-889CrossRefPubMed
11.
Zurück zum Zitat Hayase H, Tokunaga K, Nakayama T, Sugiu K, Nishida A, Arimitsu S, Hishikawa T, Ono S, Ohta M, Date I (2011) Computational fluid dynamics of carotid arteries after carotid endarterectomy or carotid artery stenting based on postoperative patient-specific computed tomography angiography and ultrasound flow data. Neurosurgery 68:1096–1101. doi:10.1227/NEU.0b013e318208f1a0, discussion 1101PubMed Hayase H, Tokunaga K, Nakayama T, Sugiu K, Nishida A, Arimitsu S, Hishikawa T, Ono S, Ohta M, Date I (2011) Computational fluid dynamics of carotid arteries after carotid endarterectomy or carotid artery stenting based on postoperative patient-specific computed tomography angiography and ultrasound flow data. Neurosurgery 68:1096–1101. doi:10.​1227/​NEU.​0b013e318208f1a0​, discussion 1101PubMed
12.
Zurück zum Zitat de Weert TT, Ouhlous M, Meijering E, Zondervan PE, Hendriks JM, van Sambeek MR, Dippel DW, van der Lugt A (2006) In vivo characterization and quantification of atherosclerotic carotid plaque components with multidetector computed tomography and histopathological correlation. Arterioscler Thromb Vasc Biol 26:2366–2372. doi:10.1161/01.ATV.0000240518.90124.57 CrossRefPubMed de Weert TT, Ouhlous M, Meijering E, Zondervan PE, Hendriks JM, van Sambeek MR, Dippel DW, van der Lugt A (2006) In vivo characterization and quantification of atherosclerotic carotid plaque components with multidetector computed tomography and histopathological correlation. Arterioscler Thromb Vasc Biol 26:2366–2372. doi:10.​1161/​01.​ATV.​0000240518.​90124.​57 CrossRefPubMed
13.
Zurück zum Zitat Hishikawa T, Iihara K, Yamada N, Ishibashi-Ueda H, Miyamoto S (2010) Assessment of necrotic core with intraplaque hemorrhage in atherosclerotic carotid artery plaque by MR imaging with 3D gradient-echo sequence in patients with high-grade stenosis. Clinical article. J Neurosurg 113:890–896. doi:10.3171/2010.3.jns091057 CrossRefPubMed Hishikawa T, Iihara K, Yamada N, Ishibashi-Ueda H, Miyamoto S (2010) Assessment of necrotic core with intraplaque hemorrhage in atherosclerotic carotid artery plaque by MR imaging with 3D gradient-echo sequence in patients with high-grade stenosis. Clinical article. J Neurosurg 113:890–896. doi:10.​3171/​2010.​3.​jns091057 CrossRefPubMed
14.
Zurück zum Zitat Yamada N, Higashi M, Otsubo R, Sakuma T, Oyama N, Tanaka R, Iihara K, Naritomi H, Minematsu K, Naito H (2007) Association between signal hyperintensity on T1-weighted MR imaging of carotid plaques and ipsilateral ischemic events. AJNR Am J Neuroradiol 28:287–292PubMed Yamada N, Higashi M, Otsubo R, Sakuma T, Oyama N, Tanaka R, Iihara K, Naritomi H, Minematsu K, Naito H (2007) Association between signal hyperintensity on T1-weighted MR imaging of carotid plaques and ipsilateral ischemic events. AJNR Am J Neuroradiol 28:287–292PubMed
15.
Zurück zum Zitat Armon MP, Yusuf SW, Whitaker SC, Gregson RH, Wenham PW, Hopkinson BR (1998) Thrombus distribution and changes in aneurysm size following endovascular aortic aneurysm repair. Eur J Vasc Endovasc Surg 16:472–476CrossRefPubMed Armon MP, Yusuf SW, Whitaker SC, Gregson RH, Wenham PW, Hopkinson BR (1998) Thrombus distribution and changes in aneurysm size following endovascular aortic aneurysm repair. Eur J Vasc Endovasc Surg 16:472–476CrossRefPubMed
16.
Zurück zum Zitat Wever JJ, Blankensteijn JD, Th M Mali WP, Eikelboom BC (2000) Maximal aneurysm diameter follow-up is inadequate after endovascular abdominal aortic aneurysm repair. Eur J Vasc Endovasc Surg 20:177–182. doi:10.1053/ejvs.1999.1051 CrossRefPubMed Wever JJ, Blankensteijn JD, Th M Mali WP, Eikelboom BC (2000) Maximal aneurysm diameter follow-up is inadequate after endovascular abdominal aortic aneurysm repair. Eur J Vasc Endovasc Surg 20:177–182. doi:10.​1053/​ejvs.​1999.​1051 CrossRefPubMed
17.
Zurück zum Zitat Yao J, van Sambeek MR, Dall’Agata A, van Dijk LC, Kozakova M, Koudstaal PJ, Roelandt JR (1998) Three-dimensional ultrasound study of carotid arteries before and after endarterectomy; analysis of stenotic lesions and surgical impact on the vessel. Stroke 29:2026–2031CrossRefPubMed Yao J, van Sambeek MR, Dall’Agata A, van Dijk LC, Kozakova M, Koudstaal PJ, Roelandt JR (1998) Three-dimensional ultrasound study of carotid arteries before and after endarterectomy; analysis of stenotic lesions and surgical impact on the vessel. Stroke 29:2026–2031CrossRefPubMed
18.
Zurück zum Zitat Kobayashi Y, Honda Y, Christie GL, Teirstein PS, Bailey SR, Brown CL, Matthews RV, De Franco AC, Schwartz RS, Goldberg S, Popma JJ, Yock PG, Fitzgerald PJ (2001) Long-term vessel response to a self-expanding coronary stent: a serial volumetric intravascular ultrasound analysis from the ASSURE Trial. A stent vs. stent ultrasound remodeling evaluation. J Am Coll Cardiol 37:1329–1334CrossRefPubMed Kobayashi Y, Honda Y, Christie GL, Teirstein PS, Bailey SR, Brown CL, Matthews RV, De Franco AC, Schwartz RS, Goldberg S, Popma JJ, Yock PG, Fitzgerald PJ (2001) Long-term vessel response to a self-expanding coronary stent: a serial volumetric intravascular ultrasound analysis from the ASSURE Trial. A stent vs. stent ultrasound remodeling evaluation. J Am Coll Cardiol 37:1329–1334CrossRefPubMed
19.
Zurück zum Zitat Murphy RE, Moody AR, Morgan PS, Martel AL, Delay GS, Allder S, MacSweeney ST, Tennant WG, Gladman J, Lowe J, Hunt BJ (2003) Prevalence of complicated carotid atheroma as detected by magnetic resonance direct thrombus imaging in patients with suspected carotid artery stenosis and previous acute cerebral ischemia. Circulation 107:3053–3058. doi:10.1161/01.CIR.0000074204.92443.37 CrossRefPubMed Murphy RE, Moody AR, Morgan PS, Martel AL, Delay GS, Allder S, MacSweeney ST, Tennant WG, Gladman J, Lowe J, Hunt BJ (2003) Prevalence of complicated carotid atheroma as detected by magnetic resonance direct thrombus imaging in patients with suspected carotid artery stenosis and previous acute cerebral ischemia. Circulation 107:3053–3058. doi:10.​1161/​01.​CIR.​0000074204.​92443.​37 CrossRefPubMed
20.
Zurück zum Zitat Farb A, Sangiorgi G, Carter AJ, Walley VM, Edwards WD, Schwartz RS, Virmani R (1999) Pathology of acute and chronic coronary stenting in humans. Circulation 99:44–52CrossRefPubMed Farb A, Sangiorgi G, Carter AJ, Walley VM, Edwards WD, Schwartz RS, Virmani R (1999) Pathology of acute and chronic coronary stenting in humans. Circulation 99:44–52CrossRefPubMed
21.
Zurück zum Zitat Aikawa H, Kodama T, Nii K, Tsutsumi M, Onizuka M, Iko M, Matsubara S, Etou H, Sakamoto K, Kazekawa K (2008) Intraprocedural plaque protrusion resulting in cerebral embolism during carotid angioplasty with stenting. Radiat Med 26:318–323. doi:10.1007/s11604-008-0231-1 CrossRefPubMed Aikawa H, Kodama T, Nii K, Tsutsumi M, Onizuka M, Iko M, Matsubara S, Etou H, Sakamoto K, Kazekawa K (2008) Intraprocedural plaque protrusion resulting in cerebral embolism during carotid angioplasty with stenting. Radiat Med 26:318–323. doi:10.​1007/​s11604-008-0231-1 CrossRefPubMed
22.
Zurück zum Zitat Henneke KH, Regar E, Konig A, Werner F, Klauss V, Metz J, Theisen K, Mudra H (1999) Impact of target lesion calcification on coronary stent expansion after rotational atherectomy. Am Heart J 137:93–99CrossRefPubMed Henneke KH, Regar E, Konig A, Werner F, Klauss V, Metz J, Theisen K, Mudra H (1999) Impact of target lesion calcification on coronary stent expansion after rotational atherectomy. Am Heart J 137:93–99CrossRefPubMed
25.
Zurück zum Zitat Tsutsumi M, Kodama T, Aikawa H, Onizuka M, Iko M, Nii K, Hamaguchi S, Etou H, Sakamoto K, Inoue R, Nakau H, Kazekawa K (2010) Fragmentation of calcified plaque after carotid artery stenting in heavily calcified circumferential stenosis. Neuroradiology 52:831–836. doi:10.1007/s00234-009-0630-8 CrossRefPubMed Tsutsumi M, Kodama T, Aikawa H, Onizuka M, Iko M, Nii K, Hamaguchi S, Etou H, Sakamoto K, Inoue R, Nakau H, Kazekawa K (2010) Fragmentation of calcified plaque after carotid artery stenting in heavily calcified circumferential stenosis. Neuroradiology 52:831–836. doi:10.​1007/​s00234-009-0630-8 CrossRefPubMed
Metadaten
Titel
Novel 3D-CT evaluation of carotid stent volume: greater chronological expansion of stents in patients with vulnerable plaques
verfasst von
Hisakazu Itami
Koji Tokunaga
Yu Okuma
Tomohito Hishikawa
Kenji Sugiu
Kentaro Ida
Isao Date
Publikationsdatum
01.09.2013
Verlag
Springer Berlin Heidelberg
Erschienen in
Neuroradiology / Ausgabe 9/2013
Print ISSN: 0028-3940
Elektronische ISSN: 1432-1920
DOI
https://doi.org/10.1007/s00234-013-1223-0

Weitere Artikel der Ausgabe 9/2013

Neuroradiology 9/2013 Zur Ausgabe

Leitlinien kompakt für die Neurologie

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Sind Frauen die fähigeren Ärzte?

30.04.2024 Gendermedizin Nachrichten

Patienten, die von Ärztinnen behandelt werden, dürfen offenbar auf bessere Therapieergebnisse hoffen als Patienten von Ärzten. Besonders gilt das offenbar für weibliche Kranke, wie eine Studie zeigt.

Akuter Schwindel: Wann lohnt sich eine MRT?

28.04.2024 Schwindel Nachrichten

Akuter Schwindel stellt oft eine diagnostische Herausforderung dar. Wie nützlich dabei eine MRT ist, hat eine Studie aus Finnland untersucht. Immerhin einer von sechs Patienten wurde mit akutem ischämischem Schlaganfall diagnostiziert.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Frühe Alzheimertherapie lohnt sich

25.04.2024 AAN-Jahrestagung 2024 Nachrichten

Ist die Tau-Last noch gering, scheint der Vorteil von Lecanemab besonders groß zu sein. Und beginnen Erkrankte verzögert mit der Behandlung, erreichen sie nicht mehr die kognitive Leistung wie bei einem früheren Start. Darauf deuten neue Analysen der Phase-3-Studie Clarity AD.

Update Neurologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.