Skip to main content
Erschienen in:

01.05.2020 | Psychosocial Aspects (SS Jaser, Section Editor)

Novel Challenges in Aging with Type 1 Diabetes

verfasst von: Jeoffrey A. Bispham, Allyson S. Hughes, Kimberly A. Driscoll, Alicia H. McAuliffe-Fogarty

Erschienen in: Current Diabetes Reports | Ausgabe 5/2020

Einloggen, um Zugang zu erhalten

Abstract

Purpose of Review

Due to treatment advancements, individuals with type 1 diabetes (T1D) are living longer, presenting a unique understudied population with advanced complex needs. This article is a review of the aging literature in T1D and identifies existing gaps while serving as a call to the research community.

Recent Findings

Recent studies have identified an association between cognitive impairment and glycemic variability, as well as increased risk and frequency of hypoglycemia in older adults with T1D. However, limited research exists about additional physical and mental health conditions and barrier to successful treatment in this population.

Summary

Older adults may experience both age- and diabetes-related barriers to diabetes management. Due to the scarcity of aging T1D research, current treatment guidelines for this age group are based on type 2 diabetes research. There is a critical need to further investigate the physical and mental effects of T1D and aging as well as public health policy; insurance challenges; and needs for support and interventions for older adults with T1D.
Literatur
25.
Zurück zum Zitat •• Gilsanz P, Schnaider Beeri M, Karter AJ, Quesenberry CP, Adams AS, Whitmer RA. Depression in type 1 diabetes and risk of dementia. Aging Ment Health. 2019;23(7):880–6. https://doi.org/10.1080/13607863.2018.1455167This study provides evidence that risk of dementia is significantly increased with the occurrence of depression in adults with type 1 diabetes aged ≥ 50. CrossRefPubMed •• Gilsanz P, Schnaider Beeri M, Karter AJ, Quesenberry CP, Adams AS, Whitmer RA. Depression in type 1 diabetes and risk of dementia. Aging Ment Health. 2019;23(7):880–6. https://​doi.​org/​10.​1080/​13607863.​2018.​1455167This study provides evidence that risk of dementia is significantly increased with the occurrence of depression in adults with type 1 diabetes aged ≥ 50. CrossRefPubMed
39.
Zurück zum Zitat Bauer S, Nauck MA. Polypharmacy in people with type 1 and type 2 diabetes is justified by current guidelines-a comprehensive assessment of drug prescriptions in patients needing inpatient treatment for diabetes-associated problems. Diabet Med. 2014;31(9):1078–85. https://doi.org/10.1111/dme.12497.CrossRefPubMed Bauer S, Nauck MA. Polypharmacy in people with type 1 and type 2 diabetes is justified by current guidelines-a comprehensive assessment of drug prescriptions in patients needing inpatient treatment for diabetes-associated problems. Diabet Med. 2014;31(9):1078–85. https://​doi.​org/​10.​1111/​dme.​12497.CrossRefPubMed
42.
Zurück zum Zitat Roussel R, Moutairou A, Riveline J-P, Gautier J-F, Potier L. 1091-P: association between mild and severe hypoglycemia in people with T1 and T2 diabetes enrolled in randomized controlled trials for assessing insulin therapy. Diabetes. 2019;68(Suppl. 1):1091. https://doi.org/10.2337/db19-1091-P.CrossRef Roussel R, Moutairou A, Riveline J-P, Gautier J-F, Potier L. 1091-P: association between mild and severe hypoglycemia in people with T1 and T2 diabetes enrolled in randomized controlled trials for assessing insulin therapy. Diabetes. 2019;68(Suppl. 1):1091. https://​doi.​org/​10.​2337/​db19-1091-P.CrossRef
48.
Zurück zum Zitat •• Chaytor NS, Barbosa-Leiker C, Ryan CM, Germine LT, Hirsch IB, Weinstock RS. Clinically significant cognitive impairment in older adults with type 1 diabetes. J Diabetes Complicat. 2019;33(1):91–7. https://doi.org/10.1016/j.jdiacomp.2018.04.003This study identified the prevalence of clinically significant cognitive impairment in older adults with type 1 diabetes and diabetes-related factors correlated with impairment. CrossRefPubMed •• Chaytor NS, Barbosa-Leiker C, Ryan CM, Germine LT, Hirsch IB, Weinstock RS. Clinically significant cognitive impairment in older adults with type 1 diabetes. J Diabetes Complicat. 2019;33(1):91–7. https://​doi.​org/​10.​1016/​j.​jdiacomp.​2018.​04.​003This study identified the prevalence of clinically significant cognitive impairment in older adults with type 1 diabetes and diabetes-related factors correlated with impairment. CrossRefPubMed
49.
Zurück zum Zitat Mattishent K, Richardson K, Dhatariya K, Savva GM, Fox C, Loke YK. The effects of hypoglycaemia and dementia on cardiovascular events, falls and fractures and all-cause mortality in older individuals: a retrospective cohort study. Diabetes Obes Metab. 2019:1–10. https://doi.org/10.1111/dom.13769. Mattishent K, Richardson K, Dhatariya K, Savva GM, Fox C, Loke YK. The effects of hypoglycaemia and dementia on cardiovascular events, falls and fractures and all-cause mortality in older individuals: a retrospective cohort study. Diabetes Obes Metab. 2019:1–10. https://​doi.​org/​10.​1111/​dom.​13769.
52.
Zurück zum Zitat Administration SA and MHS. Key substance use and mental health indicators in the United States: results from the 2017 National Survey on Drug Use and Health. Rockville, MD; 2018. https://www.samhsa.gov/data/. Accessed 10 Feb 2020. Administration SA and MHS. Key substance use and mental health indicators in the United States: results from the 2017 National Survey on Drug Use and Health. Rockville, MD; 2018. https://​www.​samhsa.​gov/​data/​. Accessed 10 Feb 2020.
Metadaten
Titel
Novel Challenges in Aging with Type 1 Diabetes
verfasst von
Jeoffrey A. Bispham
Allyson S. Hughes
Kimberly A. Driscoll
Alicia H. McAuliffe-Fogarty
Publikationsdatum
01.05.2020
Verlag
Springer US
Erschienen in
Current Diabetes Reports / Ausgabe 5/2020
Print ISSN: 1534-4827
Elektronische ISSN: 1539-0829
DOI
https://doi.org/10.1007/s11892-020-01298-9

Kompaktes Leitlinien-Wissen Innere Medizin (Link öffnet in neuem Fenster)

Mit medbee Pocketcards schnell und sicher entscheiden.
Leitlinien-Wissen kostenlos und immer griffbereit auf ihrem Desktop, Handy oder Tablet.

Neu im Fachgebiet Innere Medizin

Fortgeschrittenes Melanom: Wann den Checkpoint-Inhibitor absetzen?

Eine ICI-Therapie sollte bei Betroffenen mit fortgeschrittenem Melanom mindestens ein Jahr fortgesetzt werden. Bei anhaltendem Ansprechen kann danach offenbar ohne hohes Risiko ein Therapieabbruch erwogen werden.

Therapiestopp bei älteren MS-Kranken kann sich lohnen

Eine Analyse aus Kanada bestätigt: Setzen ältere MS-Kranke die Behandlung mit Basistherapeutika ab, müssen sie kaum mit neuen Schüben und MRT-Auffälligkeiten rechnen.

Dank Nasenspray seltener in die Notaufnahme

Durch die intranasale Applikation von Etripamil lassen sich paroxysmale supraventrikuläre Tachykardien (PSVT) oft in Eigenregie beenden. Das erspart den Betroffenen das Aufsuchen von Notfallambulanzen.

Vorhofflimmern: So häufig kommt es bei Katheterablation zu Embolien

Arterielle Embolien – insbesondere Hirnembolien - sind eine mögliche periprozedurale Komplikation bei Katheterablation von Vorhofflimmern. Wie hoch ist das Risiko? Eine Analyse von weltweit mehr als 300.000 Ablationsprozeduren gibt darüber Auskunft.

EKG Essentials: EKG befunden mit System (Link öffnet in neuem Fenster)

In diesem CME-Kurs können Sie Ihr Wissen zur EKG-Befundung anhand von zwölf Video-Tutorials auffrischen und 10 CME-Punkte sammeln.
Praxisnah, relevant und mit vielen Tipps & Tricks vom Profi.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.