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Current Cardiology Reports
Erschienen in: Current Cardiology Reports 2/2011

01.04.2011

Novel F-18–Labeled PET Myocardial Perfusion Tracers: Bench to Bedside

verfasst von: Stephan G. Nekolla, Antti Saraste

Erschienen in: Current Cardiology Reports | Ausgabe 2/2011

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Abstract

Myocardial perfusion imaging is a widely used approach to noninvasively identify myocardial ischemia and guide therapies. It is typically performed using single photon emission computed tomography. The competing technology positron emission tomography (PET) offers higher diagnostic accuracies but suffers from logistical limitations due to the use of short-lived radioisotopes. New 18F-labeled perfusion markers were introduced in the past years and offer simplified supply approaches, as known from oncologic PET imaging. This review summarizes the available literature especially from preclinical studies, but also very recent findings from early clinical trials. We discuss the consequences of long-lived radioisotopes in myocardial PET and the potential role of absolute blood flow quantification to establish efficient clinical protocols.
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Metadaten
Titel
Novel F-18–Labeled PET Myocardial Perfusion Tracers: Bench to Bedside
verfasst von
Stephan G. Nekolla
Antti Saraste
Publikationsdatum
01.04.2011
Verlag
Current Science Inc.
Erschienen in
Current Cardiology Reports / Ausgabe 2/2011
Print ISSN: 1523-3782
Elektronische ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-010-0159-9

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