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Clinical Rheumatology

Erschienen in:

01.02.2016 | Review Article

Occult spondyloarthritis in inflammatory bowel disease

verfasst von: Francesca Bandinelli, Mirko Manetti, Lidia Ibba-Manneschi

Erschienen in: Clinical Rheumatology | Ausgabe 2/2016

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Abstract

Spondyloarthritis (SpA) is a frequent extra-intestinal manifestation in patients with inflammatory bowel disease (IBD), although its real diffusion is commonly considered underestimated. Abnormalities in the microbioma and genetic predisposition have been implicated in the link between bowel and joint inflammation. Otherwise, up to date, pathogenetic mechanisms are still largely unknown and the exact influence of the bowel activity on rheumatic manifestations is not clearly explained. Due to evidence-based results of clinical studies, the interest on clinically asymptomatic SpA in IBD patients increased in the last few years. Actually, occult enthesitis and sacroiliitis are discovered in high percentages of IBD patients by different imaging techniques, mainly enthesis ultrasound (US) and sacroiliac joint X-ray examinations. Several diagnostic approaches and biomarkers have been proposed in an attempt to correctly classify and diagnose clinically occult joint manifestations and to define clusters of risk for patient screening, although definitive results are still lacking. The correct recognition of occult SpA in IBD requires an integrated multidisciplinary approach in order to identify common diagnostic and therapeutic strategies. The use of inexpensive and rapid imaging techniques, such as US and X-ray, should be routinely included in daily clinical practice and trials to correctly evaluate occult SpA, thus preventing future disability and worsening of quality of life in IBD patients.

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Titel: Occult spondyloarthritis in inflammatory bowel disease
verfasst von: Francesca Bandinelli
Mirko Manetti
Lidia Ibba-Manneschi
Publikationsdatum: 01.02.2016
Verlag: Springer London
Erschienen in: Clinical Rheumatology / Ausgabe 2/2016
Print ISSN: 0770-3198
Elektronische ISSN: 1434-9949
DOI: https://doi.org/10.1007/s10067-015-3074-z

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