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Journal of Assisted Reproduction and Genetics

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22.08.2018 | Fertility Preservation

Oocyte cryopreservation among transmasculine youth: a case series

verfasst von: Diane Chen, Lia A. Bernardi, Mary Ellen Pavone, Eve C. Feinberg, Molly B. Moravek

Erschienen in: Journal of Assisted Reproduction and Genetics | Ausgabe 11/2018

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Excerpt

Approximately 150,000 youth (ages 13–17) in the USA identify as transgender [1]. Transgender people frequently experience gender dysphoria, which refers to the affective distress that stems from incongruence between an individual’s assigned sex at birth and their gender identity [2]. Many transgender people seek gender-affirming hormone therapy (i.e., testosterone or estrogen) or surgery as a means to decrease gender dysphoria by bringing their bodies and gender identities into alignment. While these interventions are effective in reducing gender dysphoria and improving psychosocial functioning [3], many of the surgical procedures are sterilizing, and the long-term effects of gender-affirming hormones on reproductive function are unknown. …

Herman JL, Flores AR, Brown TNT, Wilson BDM, Conron KJ. Age of individuals who identify as transgender in the United States, The Williams Institute UCLA School of Law. 2017. https://williamsinstitute.law.ucla.edu/wp-content/uploads/TransAgeReport.pdf. Accessed 14 March 2018.

American Psychiatric Association. Diagnostic and statistical manual of mental disorders. fifth ed. Arlington: American Psychiatric Association; 2013.CrossRef

Costa R, Colizzi M. The effect of cross-sex hormonal treatment on gender dysphoria individuals’ mental health: a systematic review. Neuropsychiatr Dis Treat. 2016;12:1953–66.CrossRef

De Roo C, Tilleman K, T' Sjoen G, De Sutter P. Fertility options in transgender people. Int Rev Psychiatry. 2016;28:112–9.CrossRef

Wierckx K, Van Caenegem E, Pennings G, Elaut E, Dedecker D, et al. Reproductive wish in transsexual men. Hum Reprod. 2012;27:483–7.CrossRef

De Sutter P, Kira K, Verschoor A, Hotimsky A. The desire to have children and the preservation of fertility in transsexual women: a survey. Int J Transgenderism. 2002;6:215–21.

Coleman E, Bockting W, Botzer M, Cohen-Kettenis P, DeCuypere G, Feldman J, et al. Standards of care for the health of transsexual, transgender, and gender-nonconforming people, version 7. Int J Transgenderism. 2012;13:165–232.CrossRef

Ethics Committee of the American Society of Reproductive Medicine. Access to fertility services by transgender persons: an ethics committee opinion. Fertil Steril. 2015;104:1111–5.CrossRef

Hembree WC, Cohen-Kettenis PT, Gooren L, Hannema SE, Meyer WJ, Murad MH, et al. Endocrine treatment of gender-dysphoric/gender-incongruent persons: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2017;102:3869–903.CrossRef

10.

Spack NP, Edwards-Leeper L, Feldman HA, Leibowitz S, Mandel F, Diamond DA, et al. Children and adolescents with gender identity disorder referred to a pediatric medical center. Pediatrics. 2012;129:418–25.CrossRef

11.

Hsieh S, Leininger J. Resource list: clinical care programs for gender-nonconforming children and adolescents. Pediatr Ann. 2014;43:238–44.CrossRef

12.

Chen M, Fuqua J, Eugster EA. Characteristics of referrals for gender dysphoria over a 13-year period. J Adolesc Health. 2016;58:369–71.CrossRef

13.

Oktay K, Bedoschi G. Oocyte cryopreservation for fertility preservation in postpubertal female children at risk for premature ovarian failure due to accelerated follicle loss in Turner syndrome or cancer treatments. J Pediatr Adolesc Gynecol. 2014;27:342–6.CrossRef

14.

Reichman DE, Davis OK, Zaninovic N, Rosenwaks Z, Goldschlag DE. Fertility preservation using controlled ovarian hyperstimulation and oocyte cryopreservation in a premenarcheal female with myelodysplastic syndrome. Fertil Steril. 2012;98:1225–8.CrossRef

15.

Lavery SA, Islam R, Hunt J, Carby A, Anderson RA. The medical and ethical challenges of fertility preservation in teenage girls: a case series of sickle cell anaemia patients prior to bone marrow transplant. Hum Reprod. 2016;31:1501–7.CrossRef

16.

Dovey S, Krishnamurti L, Sanfilippo J, Gunawardena S, Mclendon P, Campbell M, et al. Oocyte cryopreservation in a patient with sickle cell disease prior to hematopoietic stem cell transplantation: first report. J Assist Reprod Genet. 2012;29(3):265–9.CrossRef

17.

Noyes N, Perretta RC, Fino ME, Matulewicz T, Barakat R. Use of hormone suppression then oocyte freezing to preserve reproductive capability in an adolescent girl with ovarian luteinized thecoma associated with sclerosing peritonitis. Fertil Steril. 2009;92(1):393.e11–4.CrossRef

18.

Kim TJ, Hong SW. Successful live birth from vitrified oocytes after 5 years of cryopreservation. J Assist Reprod Genet. 2011;28:73–6.CrossRef

19.

Kutteh WH, Klosky JL, Green DM, Sparrow CK, Kutteh MA, Robinson GW, et al. Ovulation induction and oocyte retrieval for fertility preservation in young adolescents newly diagnosed with medulloblastoma: a case series. J Obstet Gynaecol. 2018;38(6):878–9.CrossRef

20.

Chen D, Matson M, Macapagal K, Johnson EK, Rosoklija I, Finlayson C, et al. Attitudes toward fertility and reproductive health among transgender and gender-nonconforming adolescents. J Adolesc Health. 2018;63(1):62–8.CrossRef

21.

Armuand G, Dhejne C, Olofsson JI, Rodriguez-Wallberg KA. Transgender men’s experiences of fertility preservation: a qualitative study. Hum Reprod. 2017;32:383–90.CrossRef

22.

Finlayson C, Johnson EK, Chen D, Dabrowski E, Gosiengfiao Y, Campo-Engelstein L, et al. Proceedings of the working group session on fertility preservation for individuals with gender and sex diversity. Transgend Health. 2016;1:99–107.CrossRef

23.

Lierman S, Tilleman K, Braeckmans K, Peynshaert K, Weyers S, T’Sjoen G, et al. Fertility preservation for trans men: frozen-thawed in vitro matured oocytes collected at the time of ovarian tissue processing exhibit normal meiotic spindles. J Assist Reprod Genet. 2017;34:1449–56.CrossRef

24.

De Roo C, Lierman S, Tilleman K, Peynshaert K, Braeckmans K, Caanen M, et al. Ovarian tissue cryopreservation in female-to-male transgender people: insights into ovarian histology and physiology after prolonged androgen treatment. Reprod Biomed Online. 2017;34(6):557–66.CrossRef

25.

Futterweit W, Deligdisch L. Histopathological effects of exogenously administered testosterone in 19 female to male transsexuals. J Clin Endocrinol Metab. 1986;62:16–21.CrossRef

26.

Ikeda K, Baba T, Noguchi H, Nagasawa K, Endo T, Kiya T, et al. Excessive androgen exposure in female-to-male transsexual persons of reproductive age induces hyperplasia of the ovarian cortex and stroma but not polycystic ovary morphology. Hum Reprod. 2013;28:453–61.CrossRef

27.

Pache TD, Chadha S, Gooren LJ, Hop WC, Jaarsma KW, et al. Ovarian morphology in long-term androgen-treated female to male transsexuals. A human model for the study of polycystic ovarian syndrome? Histopathology. 1991;19:445–52.CrossRef

28.

Spinder T, Spijkstra JJ, van den Tweel JG, Burger CW, van Kessel H, et al. The effects of long term testosterone administration on pulsatile luteinizing hormone secretion and on ovarian histology in eugonadal female to male transsexual subjects. J Clin Endocrinol Metab. 1989;69:151–7.CrossRef

29.

Van Den Broecke R, Van Der Elst J, Liu J, Hovatta O, Dhont M. The female-to-male transsexual patient: a source of human ovarian cortical tissue for experimental use. Hum Reprod. 2001;16:145–7.CrossRef

30.

Grynberg M, Fanchin R, Dubost G, Colau JC, Bremont-Weil C, et al. Histology of genital tract and breast tissue after long-term testosterone administration in a female-to-male transsexual population. Reprod Biomed Online. 2010;2:553–8.CrossRef

31.

Loverro G, Resta L, Dellino M, Edoardo DN, Cascarano MA, Loverro M, et al. Uterine and ovarian changes during testosterone administration in young female-to-male transsexuals. Taiwan J Obstet Gynecol. 2016;55:686–91.CrossRef

32.

Chen D, Simons L. Ethical considerations in fertility preservation for transgender youth: a case illustration. Clin Pract Pediatr Psychol. 2018;6:93–100.CrossRef

33.

Kuwayama M, Vajta G, Kato O, Leibo SP. Highly efficient vitrification method for cryopreservation of human oocytes. Reprod BioMed Online. 2005;11:300–8.CrossRef

34.

Chen D, Simons L, Johnson EK, Lockart BA, Finlayson C. Fertility preservation for transgender adolescents. J Adolesc Health. 2017;61:120–3.CrossRef

35.

Nahata L, Tishelman AC, Caltabellotta NM, Quinn GP. Low fertility preservation utilization among transgender youth. J Adolesc Health. 2017;61:40–4.CrossRef

36.

Strang JF, Jarin J, Call D, Clark B, Wallace GL, Anthony LG, et al. Transgender youth fertility attitudes questionnaire: measure development in nonautistic and autistic transgender youth and their parents. J Adolesc Health. 2018;62:128–35.CrossRef

37.

Duncan FE. Egg quality during the pubertal transition-is youth all it’s cracked up to be? Front Endocrinol (Lausanne). 2017;8:226.CrossRef

38.

Zheng W, Zhang H, Gorre N, Risal S, Shen Y, Liu K. Two classes of ovarian primordial follicles exhibit distinct developmental dynamics and physiological functions. Hum Mol Genet. 2014;23:920–8.CrossRef

39.

Maxwell S, Noyes N, Keefe D, Berkeley AS, Goldman KN. Pregnancy outcomes after fertility preservation in transgender men. Obstet Gynecol. 2017;

40.

Cauffman E, Steinberg L. (Im) maturity of judgment in adolescence: why adolescents may be less culpable than adults. Behav Sci Law. 2000;18:741–60.CrossRef

41.

Campo-Engelstein L, Chen D. Ethical issues in pediatric and adolescent fertility preservation. In: TK Woodruff, YC Gosiengfiao, editors. Pediatric and adolescent oncofertility. Cham: Springer; 2017. p. 259–67.CrossRef

42.

Shetty P. India’s unregulated surrogacy industry. Lancet. 2012;380:1633–4.CrossRef

Titel: Oocyte cryopreservation among transmasculine youth: a case series
verfasst von: Diane Chen
Lia A. Bernardi
Mary Ellen Pavone
Eve C. Feinberg
Molly B. Moravek
Publikationsdatum: 22.08.2018
Verlag: Springer US
Erschienen in: Journal of Assisted Reproduction and Genetics / Ausgabe 11/2018
Print ISSN: 1058-0468
Elektronische ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-018-1292-4

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Oocyte cryopreservation among transmasculine youth: a case series

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