The authors declare that they have no competing interests.
JCFL and WML planned the study design. JCFL drafted the manuscript and performed the statistical analysis. WML participated in the literature search, interpretation, and extensive revision of the manuscript. Both authors read and approved the final manuscript.
This study compared the rates of mortality, medical complication, and reoperation after fixation surgery for displaced femoral neck fracture with those after hemiarthroplasty surgery for undisplaced femoral neck fracture using competing risk analysis in inpatients aged 60 years and above from a population database in Taiwan.
We identified 13,772 subjects who underwent fixation for undisplaced cervical fracture and 13,772 matched controls who underwent hemiarthroplasty for displaced cervical fracture from 1998 to 2007, and followed them up until the end of 2009. The outcomes of patients who received internal fixation for undisplaced fracture and those of patients who received hemiarthroplasty for displaced fracture were compared.
The 3-month, 2-year, and 10-year mortality rates were 4.9 %, 22.1 %, and 67.1 % for fixation, and 5.6 %, 23.8 %, and 71.0 % for hemiarthroplasty, respectively. The 3-month, 2-year, and 10-year cumulative incidence rates of the first reoperation were 7.4 %, 18.1 %, and 27.7 % for fixation and 6.3 %, 12.0 %, and 22.3 % for hemiarthroplasty, respectively. The 3-month cumulative incidence rates of the first medical complication were 14.4 % for fixation and 15.4 % for hemiarthroplasty, respectively. Hemiarthroplasty had a 1.09 times (95 % CI: 1.05–1.12) higher hazard ratio for overall death than fixation. However, fixation had a 1.36 times (95 % CI: 1.29–1.43) higher subdistribution hazard ratio for first reoperation than hemiarthroplasty after adjusting for gender, age, and comorbidities.
The short-term overall mortality and medical complication rate of fixation for undisplaced fracture were slightly lower than those of hemiarthroplasty for displaced fracture. However, the short-term cumulative incidence of first reoperation after fixation was significantly higher than that for hemiarthroplasty. Further prospective studies or clinical trials based on the competing risk model, and which include important risk factors, are necessary to quantify the adjusted effects more precisely.
Hui AC, Anderson GH, Choudhry R, Boyle J, Gregg PJ. Internal fixation or hemiarthroplasty for undisplaced fractures of the femoral neck in octogenarians. J Bone Joint Surg Br. 1994;76(6):891–4. PubMed
Beyersmann J. Competing risks and multistate models with R. New York: Springer; 2011.
Pintilie M. Competing risks: a practical perspective. Chichester, England. Hoboken, NJ: John Wiley & Sons; 2006. CrossRef
- Outcomes after fixation for undisplaced femoral neck fracture compared to hemiarthroplasty for displaced femoral neck fracture among the elderly
Jeff Chien-Fu Lin
- BioMed Central
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