Erschienen in:
01.02.2011 | General Gynecology
Oxidant/antioxidant status in premenstrual syndrome
verfasst von:
Candan Iltemir Duvan, Ahmet Cumaoglu, Nilgun Ozturk Turhan, Cimen Karasu, Hasan Kafali
Erschienen in:
Archives of Gynecology and Obstetrics
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Ausgabe 2/2011
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Abstract
Purpose
To investigate oxidant/antioxidant status in premenstrual syndrome (PMS).
Methods
Study group (n = 20) consisted of PMS and control group (n = 21) consisted of normal menstruating women. The serum oxidant status was assessed by the lipid hydroperoxide (LHP), malondialdehyde (MDA) and protein carbonyl (PC); the antioxidant status was assessed by the total thiol (T-SH) and total antioxidant capacity (TAC).
Results
The study and control groups revealed no statistical difference, in terms of day 3 LHP, MDA, PC, T-SH and TAC levels. There were no significant differences between groups in terms of day 21 MDA, PC and T-SH levels. However, day 21 LHP levels were increased and TAC levels were decreased in the study group compared with the control group.
Conclusion
Increased oxidative stress and reduced antioxidant capacity may occur in PMS. It can be speculated that the imbalance of oxidant/antioxidant systems may be a cause or the consequence of the various stress symptoms in PMS.