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Erschienen in: The European Journal of Health Economics 7/2020

12.05.2020 | Original Paper

Patterns of care and cost profiles of women with breast cancer in Italy: EPICOST study based on real world data

verfasst von: Silvia Francisci, Stefano Guzzinati, Giulia Capodaglio, Daniela Pierannunzio, Sandra Mallone, Andrea Tavilla, Tania Lopez, Susanna Busco, Walter Mazzucco, Catia Angiolini, Manuel Zorzi, Diego Serraino, Alessandro Barchielli, Mario Fusco, Fabrizio Stracci, Fortunato Bianconi, Massimo Rugge, Silvia Iacovacci, Antonio Giampiero Russo, Rosanna Cusimano, Anna Gigli

Erschienen in: The European Journal of Health Economics | Ausgabe 7/2020

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Abstract

Objectives

To estimate total direct health care costs associated to diagnosis and treatment of women with breast cancer in Italy, and to investigate their distribution by service type according to the disease pathway and patient characteristics.

Methods

Data on patients provided by population-based Cancer Registries are linked at individual level with data on health-care services and corresponding claims from administrative databases. A combination of cross-sectional approach and a threephase of care decomposition model with initial, continuing and final phases-of-care defined according to time occurred since diagnosis and disease outcome is adopted. Direct estimation of cancer-related costs is obtained.

Results

Study cohort included 49,272 patients, 15.2% were in the initial phase absorbing 42% of resources, 79.7% in the continuing phase absorbing 44% of resources and 5.1% in the final phase absorbing 14% of resources. Hospitalization was the most important cost driver, accounting for over 55% of the total costs.

Conclusions

This paper represents the first attempt in Italy to estimate the economic burden of cancer at population level taking into account the entire disease pathway and using multiple current health care databases. The evidence produced by the study can be used to better plan resources allocation. The model proposed is replicable to countries with individual health care information on services and claims.
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Literatur
1.
Zurück zum Zitat Sullivan, R., Peppercorn, J., Sikora, K., Zalcberg, J., Meropol, N.J., Amir, E., et al.: Delivering affordable cancer in high -income countries. Lancet Oncol 12, 933–980 (2011)CrossRef Sullivan, R., Peppercorn, J., Sikora, K., Zalcberg, J., Meropol, N.J., Amir, E., et al.: Delivering affordable cancer in high -income countries. Lancet Oncol 12, 933–980 (2011)CrossRef
4.
Zurück zum Zitat de Moor, J.S., Mariotto, A.B., Parry, C., Alfano, C.M., Padgett, L., Kent, E.E., et al.: Cancer Survivors in the United States: prevalence across the survivorship trajectory and implications for care. Cancer Epidemiol Biomark Prev 22(4), 561–570 (2013)CrossRef de Moor, J.S., Mariotto, A.B., Parry, C., Alfano, C.M., Padgett, L., Kent, E.E., et al.: Cancer Survivors in the United States: prevalence across the survivorship trajectory and implications for care. Cancer Epidemiol Biomark Prev 22(4), 561–570 (2013)CrossRef
5.
Zurück zum Zitat Mariotto, A.B., Yabroff, K.R., Shao, Y., Feuer, E.J., Brown, M.L.: Projections of the cost of cancer care in the United States: 2010–2020. Natl Cancer Inst 103, 117–128 (2011)CrossRef Mariotto, A.B., Yabroff, K.R., Shao, Y., Feuer, E.J., Brown, M.L.: Projections of the cost of cancer care in the United States: 2010–2020. Natl Cancer Inst 103, 117–128 (2011)CrossRef
6.
Zurück zum Zitat Jonsson, B., Hofmarcher, T., Lindgren, P., Wilking, N.: The cost and burden of cancer in the European Union 1995 e 2014. Eur J Cancer 66, 162–170 (2016)CrossRef Jonsson, B., Hofmarcher, T., Lindgren, P., Wilking, N.: The cost and burden of cancer in the European Union 1995 e 2014. Eur J Cancer 66, 162–170 (2016)CrossRef
7.
Zurück zum Zitat Luengo-Fernandez, R., Leal, J., Gray, A., Sullivan, R.: Economic burden of cancer across the European Union: a population-based cost analysis. Lancet Oncol 14, 1165–1174 (2013)CrossRef Luengo-Fernandez, R., Leal, J., Gray, A., Sullivan, R.: Economic burden of cancer across the European Union: a population-based cost analysis. Lancet Oncol 14, 1165–1174 (2013)CrossRef
9.
Zurück zum Zitat Warren, J.L., Yabroff, K.R., Meekins, A., Topor, M., Lamont, E.B., Brown, M.L.: Evaluation of trends in the cost of initial cancer treatment. J Natl Cancer Inst 100, 888–897 (2008)CrossRef Warren, J.L., Yabroff, K.R., Meekins, A., Topor, M., Lamont, E.B., Brown, M.L.: Evaluation of trends in the cost of initial cancer treatment. J Natl Cancer Inst 100, 888–897 (2008)CrossRef
10.
Zurück zum Zitat Yabroff, K.R., Lamont, E.B., Mariotto, A., Warren, J.L., Topor, M., Meekins, A., et al.: Cost of care for elderly cancer patients in the United States. J Natl Cancer Inst 100, 630–641 (2008)CrossRef Yabroff, K.R., Lamont, E.B., Mariotto, A., Warren, J.L., Topor, M., Meekins, A., et al.: Cost of care for elderly cancer patients in the United States. J Natl Cancer Inst 100, 630–641 (2008)CrossRef
11.
Zurück zum Zitat Banegas, M.P., Yabroff, K.R., O'Keeffe-Rosetti, M.C., Ritzwoller, D.P., Fishman, P.A., Salloum, R.G., et al.: Medical care costs associated with cancer in integrated delivery system. J Natl Compr Canc Netw 16(4), 402–410 (2018)CrossRef Banegas, M.P., Yabroff, K.R., O'Keeffe-Rosetti, M.C., Ritzwoller, D.P., Fishman, P.A., Salloum, R.G., et al.: Medical care costs associated with cancer in integrated delivery system. J Natl Compr Canc Netw 16(4), 402–410 (2018)CrossRef
12.
Zurück zum Zitat De Oliveira, C., Pataky, R., Bremner, K.E., Rangrej, J., Chan, K.K., Cheung, W.Y., et al.: Estimating the cost of cancer care in British Columbia and Ontario: a Canadian inter-provincial comparison. Healthc Policy 12(3), 95 (2017)PubMedPubMedCentral De Oliveira, C., Pataky, R., Bremner, K.E., Rangrej, J., Chan, K.K., Cheung, W.Y., et al.: Estimating the cost of cancer care in British Columbia and Ontario: a Canadian inter-provincial comparison. Healthc Policy 12(3), 95 (2017)PubMedPubMedCentral
13.
Zurück zum Zitat Giuliani, J., Bonetti, A.: The pharmacological costs of first-line therapies in unselected patients with advanced colorectal cancer: a review of published phase III trials. Clin Colorectal Cancer 15(4), 277–284 (2016)CrossRef Giuliani, J., Bonetti, A.: The pharmacological costs of first-line therapies in unselected patients with advanced colorectal cancer: a review of published phase III trials. Clin Colorectal Cancer 15(4), 277–284 (2016)CrossRef
14.
Zurück zum Zitat Francisci, S., Guzzinati, S., Mezzetti, M., Crocetti, E., Giusti, F., Miccinesi, G., et al.: Cost profiles of colorectal cancer patients in Italy based on individual patterns of care. BMC Cancer 13, 329 (2013)CrossRef Francisci, S., Guzzinati, S., Mezzetti, M., Crocetti, E., Giusti, F., Miccinesi, G., et al.: Cost profiles of colorectal cancer patients in Italy based on individual patterns of care. BMC Cancer 13, 329 (2013)CrossRef
15.
Zurück zum Zitat Russo, A., Autelitano, M., Bisanti, L.: Frequency and cost of chemotherapy-related serious adverse effects in a population sample of women with breast cancer. J Natl Cancer Inst 98, 24 (2006) Russo, A., Autelitano, M., Bisanti, L.: Frequency and cost of chemotherapy-related serious adverse effects in a population sample of women with breast cancer. J Natl Cancer Inst 98, 24 (2006)
17.
Zurück zum Zitat Giorgi, D., Giordano, L., Ventura, L., Frigerio, A., Paci, E., Zappa, M.: Mammography breast cancer screening in Italy: 2010 survey. Epidemiol Prev 36(6suppl.1), 8–27 (2012)PubMed Giorgi, D., Giordano, L., Ventura, L., Frigerio, A., Paci, E., Zappa, M.: Mammography breast cancer screening in Italy: 2010 survey. Epidemiol Prev 36(6suppl.1), 8–27 (2012)PubMed
18.
Zurück zum Zitat Corti, M.C., Avossa, F., Schievano, E., Gallina, P., Ferroni, E., Alba, N., et al.: A case-mix classification system for explaining healthcare costs using administrative data in Italy. Eur J Int Med 54, 13–16 (2018)CrossRef Corti, M.C., Avossa, F., Schievano, E., Gallina, P., Ferroni, E., Alba, N., et al.: A case-mix classification system for explaining healthcare costs using administrative data in Italy. Eur J Int Med 54, 13–16 (2018)CrossRef
Metadaten
Titel
Patterns of care and cost profiles of women with breast cancer in Italy: EPICOST study based on real world data
verfasst von
Silvia Francisci
Stefano Guzzinati
Giulia Capodaglio
Daniela Pierannunzio
Sandra Mallone
Andrea Tavilla
Tania Lopez
Susanna Busco
Walter Mazzucco
Catia Angiolini
Manuel Zorzi
Diego Serraino
Alessandro Barchielli
Mario Fusco
Fabrizio Stracci
Fortunato Bianconi
Massimo Rugge
Silvia Iacovacci
Antonio Giampiero Russo
Rosanna Cusimano
Anna Gigli
Publikationsdatum
12.05.2020
Verlag
Springer Berlin Heidelberg
Erschienen in
The European Journal of Health Economics / Ausgabe 7/2020
Print ISSN: 1618-7598
Elektronische ISSN: 1618-7601
DOI
https://doi.org/10.1007/s10198-020-01190-z

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