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Erschienen in:

01.04.2015 | Short Communication

Patterns of peripheral neuropathy in ART-naïve patients initiating modern ART regimen

verfasst von: Anthony J. Lee, Ronald J. Bosch, Scott R. Evans, Kunling Wu, Taylor Harrison, Philip Grant, David B. Clifford

Erschienen in: Journal of NeuroVirology | Ausgabe 2/2015

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Abstract

The purpose of this study was to evaluate associations of pre-ART CD4 with peripheral neuropathy (PN) and estimate the prevalence of PN in HIV-positive patients starting modern combination antiretroviral therapy (cART) regimens. ART-naïve subjects initiating cART were followed longitudinally and screened for signs/symptoms of PN. Lower pre-ART CD4 count was associated with post-ART PN. After 7 years (n = 117), the prevalence (95 % CI) of PN and SPN were 31 % (23, 40 %) and 5 % (2, 11 %) with pre-ART CD4 count >250 copies/μL. PN continues to be identified in HIV-infected individuals on modern cART by targeted assessment but is generally without symptoms.

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Titel: Patterns of peripheral neuropathy in ART-naïve patients initiating modern ART regimen
verfasst von: Anthony J. Lee
Ronald J. Bosch
Scott R. Evans
Kunling Wu
Taylor Harrison
Philip Grant
David B. Clifford
Publikationsdatum: 01.04.2015
Verlag: Springer US
Erschienen in: Journal of NeuroVirology / Ausgabe 2/2015
Print ISSN: 1355-0284
Elektronische ISSN: 1538-2443
DOI: https://doi.org/10.1007/s13365-015-0327-1

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