Background
The structure of PEG10 gene
The expression levels of PEG10 in cancers
The expression levels of PEG10 in normal and cancer tissues
Tumors | Type | Methods | Expression | References |
---|---|---|---|---|
HCC | Primary HCC | IHC | 15/16a | [9] |
HCC tissues and cell lines | cDNA microarray | Significantly higher | [16] | |
HCC cell lines | QPCR | 18/20b | [17] | |
Primary HCC | QPCR | Significantly higher | ||
HCC tissues | IHC | 148/218a | [19] | |
Pancreatic carcinoma | Pancreatic carcinoma tissues | IHC | 85/160b | [20] |
Breast cancer | Ductal carcinoma | IHC | 6/11a | [10] |
Invasive ductal carcinomas | IHC | 7/22a | ||
Breast cancer tissue (n = 161) | IHC | 36%a | ||
Prostate cancer | Prostate cancer tissue (n = 30) | IHC | 37%a | [10] |
Gallbladder carcinoma | Gallbladder adenocarcinoma tissues | IHC | 52/108a | [21] |
Thyroid cancer | 24 thyroid cancer tissues and 14 normal thyroid tissues | QPCR | Significantly higher (P = 0.034) | [22] |
OSCC | OSCC tissues | QPCR | 83/118b | [23] |
Colon cancer | Colon cancer tissues | QPCR and WB | 9/20a | [24] |
Enchondromas | Enchondromas tissues | IHC and QPCR | Strongly positive expression | [25] |
B-CLL | B-CLL PBMNCs | QPCR | 40/42b | [26] |
Cancer type | Accession number | Number of samples (tumor/normal) | P-value | References |
---|---|---|---|---|
Upregulated
| ||||
Hepatocellular carcinoma | GSE14520 | 233/233 | < 0.0001 | |
Breast carcinoma | GSE10780 | 42/143 | 0.0002 | [59] |
Gastric cancer | GSE13861 | 71/19 | 0.0388 | [60] |
Ovarian cancer | GSE14407 | 12/12 | 0.0438 | [61] |
Downregulated
| ||||
Pancreatic cancer | GSE28735 | 45/45 | 0.0003 | |
Colorectal cancer | GSE32323 | 17/17 | 0.0011 | [64] |
Insignificant
| ||||
Melanoma | GSE3189 | 45/7 | 0.0848 | [65] |
Bladder cancer | GSE3167 | 41/9 | 0.1243 | [66] |
Acute lymphoblastic leukemia | GSE26713 | 117/7 | 0.2168 | [67] |
Renal clear cell carcinoma | GSE36895 | 23/23 | 0.2445 | [68] |
Esophageal carcinoma | GSE23400 | 53/53 | 0.2526 | |
Nasopharyngeal carcinoma | GSE12452 | 31/10 | 0.2710 | |
Lung cancer | GSE30219 | 293/14 | 0.2938 | [74] |
Prostate cancer | GSE6919 | 58/58 | 0.7478 |