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BioDrugs
Erschienen in: BioDrugs 5/2013

01.10.2013 | Adis Drug Clinical Q&A

Pegylated Liposomal Doxorubicin: A Guide to Its Use in Various Malignancies

verfasst von: Katherine A. Lyseng-Williamson, Sean T. Duggan, Gillian M. Keating

Erschienen in: BioDrugs | Ausgabe 5/2013

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Abstract

Pegylated liposomal doxorubicin (Caelyx® [EU], Doxil® [USA]) represents an improved formulation of conventional doxorubicin, with reduced cardiotoxicity and an improved pharmacokinetic profile. As shown by evidence from clinical trials, intravenous pegylated liposomal doxorubicin is a useful option in the treatment of various malignancies, including metastatic breast cancer, ovarian cancer, multiple myeloma, and AIDS-related Kaposi sarcoma. It has a favourable safety profile relative to conventional doxorubicin and other available chemotherapy agents.
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Metadaten
Titel
Pegylated Liposomal Doxorubicin: A Guide to Its Use in Various Malignancies
verfasst von
Katherine A. Lyseng-Williamson
Sean T. Duggan
Gillian M. Keating
Publikationsdatum
01.10.2013
Verlag
Springer International Publishing
Erschienen in
BioDrugs / Ausgabe 5/2013
Print ISSN: 1173-8804
Elektronische ISSN: 1179-190X
DOI
https://doi.org/10.1007/s40259-013-0070-1

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