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Magnetic Resonance Materials in Physics, Biology and Medicine

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13.07.2022 | Research Article

Physical limits to human brain B0 shimming with spherical harmonics, engineering implications thereof

verfasst von: Bruno Pinho Meneses, Alexis Amadon

Erschienen in: Magnetic Resonance Materials in Physics, Biology and Medicine | Ausgabe 6/2022

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Abstract

Objective

As the MRI main magnetic field rises for improved signal-to-noise ratio, susceptibility-induced B0-inhomogeneity increases proportionally, aggravating related artifacts. Considering only susceptibility disparities between air and biological tissue, we explore the topological conditions for which perfect shimming could be performed in a Region of Interest (ROI) such as the human brain or part thereof.

Materials and methods

After theoretical considerations for perfect shimming, spherical harmonic (SH) shimming simulations of very high degree are performed, based on a 100-subject database of 1.7-mm-resolved brain fieldmaps acquired at 3T . In addition to the whole brain, shimmed ROIs include slabs targeting the prefrontal cortex, both or single temporal lobes, or spheres in the frontal brain above the nasal sinus.

Results and discussion

We show “perfect” SH shimming is possible only if the ROI can be contained in a sphere that does not enclose sources of magnetic field inhomogeneity, which are gathered at the air-tissue interface. We establish a \(\sim{13}\)Hz inhomogeneity hard shim limit at 7T for whole brain SH shimming, that can only be attained at shimming degree higher than 90. On the other hand, under limited power and SH degree resources, 3D region-specific shimming is shown to greatly improve homogeneity in critical zones such as the prefrontal cortex and around ear canals.

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A ball \({\mathcal {B}}(R,\varvec{c})\) of radius R centered at \(\varvec{c}\in {\mathbb {R}}^3\) is defined as the set of \(\varvec{x}\in {\mathbb {R}}^3\) such that \(\vert \varvec{x}-\varvec{c}\vert <R\).

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Titel: Physical limits to human brain B0 shimming with spherical harmonics, engineering implications thereof
verfasst von: Bruno Pinho Meneses
Alexis Amadon
Publikationsdatum: 13.07.2022
Verlag: Springer International Publishing
Erschienen in: Magnetic Resonance Materials in Physics, Biology and Medicine / Ausgabe 6/2022
Print ISSN: 0968-5243
Elektronische ISSN: 1352-8661
DOI: https://doi.org/10.1007/s10334-022-01025-3

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Physical limits to human brain B0 shimming with spherical harmonics, engineering implications thereof

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Objective

Materials and methods

Results and discussion

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