Erschienen in:
01.09.2006 | Research Letter
Plasma concentrations of vascular endothelial growth factor are associated with peripheral oedema in patients treated with thiazolidinedione
verfasst von:
M. Emoto, N. Fukuda, Y. Nakamori, A. Taguchi, S. Okuya, Y. Oka, Y. Tanizawa
Erschienen in:
Diabetologia
|
Ausgabe 9/2006
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Excerpt
To the Editor Thiazolidinediones are widely used in patients with type 2 diabetes. In addition to lowering plasma glucose, this class of drugs may reduce the risk of cardiovascular diseases in patients with diabetes. Despite the beneficial effect of thiazolidinediones, their use is sometimes associated with peripheral oedema. This is the most frequent adverse effect leading to discontinued treatment with thiazolidinediones in Japan. However, the mechanism by which thiazolidinediones induce oedema remains to be established. …