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Erschienen in:

19.02.2018

Point shear wave elastography of the pancreas in patients with cystic fibrosis: a comparison with healthy controls

verfasst von: Matthias Hermann Christian Pfahler, Wolfgang Kratzer, Michael Leichsenring, Tilmann Graeter, Stefan Andreas Schmidt, Inka Wendlik, Elisabeth Lormes, Julian Schmidberger, Dorit Fabricius

Erschienen in: Abdominal Radiology | Ausgabe 9/2018

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Abstract

Purpose

Manifestations of cystic fibrosis in the pancreas are gaining in clinical importance as patients live longer. Conventional ultrasonography and point shear wave elastography (pSWE) imaging are non-invasive and readily available diagnostic methods that are easy to perform. The aim of this study was to perform conventional ultrasonography and obtain pSWE values in the pancreases of patients with cystic fibrosis and to compare the findings with those of healthy controls.

Methods

27 patients with cystic fibrosis (13 women/14 men; mean age 27.7 ± 13.7 years; range 9–58 years) and 60 healthy control subjects (30 women/30 men; mean age 30.3 ± 10.0 years; range 22–55 years) underwent examinations of the pancreas with conventional ultrasound and pSWE imaging.

Results

Patients with cystic fibrosis have an echogenic pancreatic parenchyma. We found cystic lesions of the pancreas in six patients. pSWE imaging of the pancreatic parenchyma gave significantly lower shear wave velocities in patients with cystic fibrosis than in the control group (1.01 m/s vs 1.30 m/s; p < 0.001).

Conclusions

Using pSWE imaging in vivo, we have shown that the pancreas is considerably softer in patients with cystic fibrosis than in a healthy control population.

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Titel: Point shear wave elastography of the pancreas in patients with cystic fibrosis: a comparison with healthy controls
verfasst von: Matthias Hermann Christian Pfahler
Wolfgang Kratzer
Michael Leichsenring
Tilmann Graeter
Stefan Andreas Schmidt
Inka Wendlik
Elisabeth Lormes
Julian Schmidberger
Dorit Fabricius
Publikationsdatum: 19.02.2018
Verlag: Springer US
Erschienen in: Abdominal Radiology / Ausgabe 9/2018
Print ISSN: 2366-004X
Elektronische ISSN: 2366-0058
DOI: https://doi.org/10.1007/s00261-018-1479-2

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Point shear wave elastography of the pancreas in patients with cystic fibrosis: a comparison with healthy controls