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Current Neurology and Neuroscience Reports

Erschienen in:

31.07.2023

Polypharmacy in Multiple Sclerosis: Prevalence, Risks, and Mitigation Strategies

verfasst von: W. Daniel Chapman, Megan C. Herink, Michelle H. Cameron, Dennis Bourdette

Erschienen in: Current Neurology and Neuroscience Reports | Ausgabe 9/2023

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Abstract

Purpose of Review

Polypharmacy, the use of ≥ 5 medications, is common in people with multiple sclerosis and is associated with negative outcomes. The use of multiple medications is common for symptom management in people with multiple sclerosis, but risks drug-drug interactions and additive side effects. Multiple sclerosis providers should therefore focus on the appropriateness and risks versus benefits of pharmacotherapy in each patient. This review describes the prevalence and risks associated with polypharmacy in people with multiple sclerosis and offers strategies to identify and mitigate inappropriate polypharmacy.

Recent Findings

Research in people with multiple sclerosis has identified risk factors and negative outcomes associated with polypharmacy. Medication class-specific investigations highlight their contribution to potentially inappropriate polypharmacy in people with multiple sclerosis.

Summary

People with multiple sclerosis are at risk for inappropriate polypharmacy. Multiple sclerosis providers should review medications and consider their appropriateness and potential for deprescribing within the context of each patient.

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Titel: Polypharmacy in Multiple Sclerosis: Prevalence, Risks, and Mitigation Strategies
verfasst von: W. Daniel Chapman
Megan C. Herink
Michelle H. Cameron
Dennis Bourdette
Publikationsdatum: 31.07.2023
Verlag: Springer US
Erschienen in: Current Neurology and Neuroscience Reports / Ausgabe 9/2023
Print ISSN: 1528-4042
Elektronische ISSN: 1534-6293
DOI: https://doi.org/10.1007/s11910-023-01289-9

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Abstract

Purpose of Review

Recent Findings

Summary

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