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01.07.2009 | Short Report

Possible association of Down syndrome and exstrophy–epispadias complex: report of two new cases and review of the literature

verfasst von: Heiko Reutter, Arend Bökenkamp, Anne-Karolin Ebert, Wolfgang Rösch, Thomas M. Boemers, Markus M. Nöthen, Michael Ludwig

Erschienen in: European Journal of Pediatrics | Ausgabe 7/2009

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Abstract

In the past, several midline defects have been associated with Down syndrome (DS) on a regular basis, e.g. heart defects, cleft lip and palate, neural tube defects, omphalocele and anal atresia. The exstrophy–epispadias complex (EEC) represents a rare midline defect, rarely described in association with DS. Here, we report on the co-occurrence of DS and EEC in two, so far, unreported cases and present a review of the literature. We suggest that EEC represents a rare but inherent part in the spectrum of DS-associated midline defects.

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Titel: Possible association of Down syndrome and exstrophy–epispadias complex: report of two new cases and review of the literature
verfasst von: Heiko Reutter
Arend Bökenkamp
Anne-Karolin Ebert
Wolfgang Rösch
Thomas M. Boemers
Markus M. Nöthen
Michael Ludwig
Publikationsdatum: 01.07.2009
Verlag: Springer-Verlag
Erschienen in: European Journal of Pediatrics / Ausgabe 7/2009
Print ISSN: 0340-6199
Elektronische ISSN: 1432-1076
DOI: https://doi.org/10.1007/s00431-008-0852-5

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