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Erschienen in: Breast Cancer Research and Treatment 3/2010

01.10.2010 | Invited Commentary

Predicting skeletal complications in metastatic breast cancer raises challenges

verfasst von: Catherine Van Poznak

Erschienen in: Breast Cancer Research and Treatment | Ausgabe 3/2010

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Excerpt

Breast cancer is a common diagnosis and is annually responsible for the deaths of over 400,000 women worldwide [1]. Approximately, 75% of patients with metastatic breast cancer develop bone metastases [2]. Once affected by tumor, the bone may be painful and may be at risk for skeletal related events (SREs) including fracture, need for surgery or radiation to bone, or spinal cord compression. Hypercalcemia of malignancy (HCM) may also be considered an SRE, but it is often categorized as a separate adverse event. In addition, bone metastases can be associated with marrow infiltration and disruption of hematopoiesis. Not only do bone metastases implicate an incurable diagnosis, bone metastases associate with pain, decreased quality of life, and significant health care expenditure [3]. …
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Metadaten
Titel
Predicting skeletal complications in metastatic breast cancer raises challenges
verfasst von
Catherine Van Poznak
Publikationsdatum
01.10.2010
Verlag
Springer US
Erschienen in
Breast Cancer Research and Treatment / Ausgabe 3/2010
Print ISSN: 0167-6806
Elektronische ISSN: 1573-7217
DOI
https://doi.org/10.1007/s10549-010-1104-8

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