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Erschienen in: European Spine Journal 3/2016

01.03.2016 | Original Article

Predictors of inpatient morbidity and mortality in adult spinal deformity surgery

verfasst von: Nancy Worley, Bryan Marascalchi, Cyrus M. Jalai, Sun Yang, Bassel Diebo, Shaleen Vira, Anthony Boniello, Virginie Lafage, Peter G. Passias

Erschienen in: European Spine Journal | Ausgabe 3/2016

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Abstract

Purpose

This nationwide study identifies ASD surgical risk factors for morbidity/mortality.

Methods

NIS discharges from 2001 to 2010 aged 25+ with scoliosis diagnoses, 4+ levels fused, and procedural codes for anterior and/or posterior thoracic and/or lumbar spinal fusion and refusion were included. Demographics, comorbidities and procedure-related complications were determined for each subgroup (degenerative, congenital, idiopathic, other). Multivariate analysis reported as [OR (95 % CI)].

Results

11,982 discharges were identified. Morbidity, excluding device-related, and mortality rates were 50.81 and 0.28 %, respectively. Certain comorbidities were associated with increased morbidity/mortality: congestive heart failure (CHF) [1.62 (1.42–1.84)] [5.67 (3.30–9.73)], coagulopathy [3.52 (3.22–3.85)] [2.32 (1.44–3.76)], electrolyte imbalance [2.65 (2.52–2.79)] [4.63 (3.15–6.81)], pulmonary circulation disorders [9.45 (7.45–11.99)] [8.94 (4.43–18.03)], renal failure [1.29 (1.13–1.47)] [5.51 (2.57–11.82)], and pathologic weight loss [2.38 (2.01–2.81)] [7.28 (4.36–12.14)]. Chronic pulmonary disease was associated with higher morbidity [1.08 (1.02–1.14)]; liver disease was linked to increased mortality [36.09 (16.16–80.59)]. 9+ level fusions had increased morbidity vs 4–8 level fusions [1.69 (1.61–1.78)] and refusions [1.08 (1.02–1.14)]. Idiopathic scoliosis was associated with decreased morbidity vs all other subgroups [0.85 (0.80–0.91)]. Age >65 was associated with increased morbidity and mortality vs 25–64 group [1.09 (1.05–1.14)] [3.49 (2.31–5.29)]. Females had increased morbidity [1.18 (1.13–1.23)] and decreased mortality [0.30 (0.21–0.44)]. Mean comorbidity index (0.55) and age (64.38) for degenerative cohort were higher vs all other subgroups (P < 0.0001).

Conclusions

Longer fusions were associated with increased morbidity. Age >65 was associated with increased morbidity/mortality, while females were associated with increased morbidity but decreased mortality. Idiopathic scoliosis had decreased morbidity. Degenerative ASD cases had higher comorbidity indices, potentially due to older age. This study is clinically useful for patient education, surgical decision-making, and optimizing patient outcomes.
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Metadaten
Titel
Predictors of inpatient morbidity and mortality in adult spinal deformity surgery
verfasst von
Nancy Worley
Bryan Marascalchi
Cyrus M. Jalai
Sun Yang
Bassel Diebo
Shaleen Vira
Anthony Boniello
Virginie Lafage
Peter G. Passias
Publikationsdatum
01.03.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
European Spine Journal / Ausgabe 3/2016
Print ISSN: 0940-6719
Elektronische ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-015-4104-x

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