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Breast Cancer Research

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01.10.2013 | Viewpoint

Pregnancy offers new insights into mechanisms of breast cancer risk and resistance

verfasst von: D Joseph Jerry, Grace Makari-Judson, Giovanna M Crisi, Karen A Dunphy

Erschienen in: Breast Cancer Research | Ausgabe 5/2013

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Abstract

Pregnancy induces long-lasting changes in gene expression that are associated with a reduction in breast cancer risk. Although several mechanisms have been proposed to mediate the reduction in breast cancer risk among parous women, recent studies focus attention on progenitor cells as major targets. The results suggest new biomarkers that may improve risk prediction and provide endpoints for assessment of clinical responses to prophylactic therapies.

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Titel: Pregnancy offers new insights into mechanisms of breast cancer risk and resistance
verfasst von: D Joseph Jerry
Grace Makari-Judson
Giovanna M Crisi
Karen A Dunphy
Publikationsdatum: 01.10.2013
Verlag: BioMed Central
Erschienen in: Breast Cancer Research / Ausgabe 5/2013
Elektronische ISSN: 1465-542X
DOI: https://doi.org/10.1186/bcr3482

Springer Medizin

Pregnancy offers new insights into mechanisms of breast cancer risk and resistance

Abstract

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Springer Medizin

Abstract

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