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Journal of Public Health

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01.10.2017 | Original Article

Prevalence of childhood diarrhea and associated risk factors in Dire Dawa, eastern Ethiopia

verfasst von: Mohammed Mekonnen, Biftu Geda, Zelalem Teklemariam, Fitsum Weldegebreal, Senthilkumar Balakrishnan

Erschienen in: Journal of Public Health | Ausgabe 1/2018

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Abstract

Aim

Childhood diarrhea caused by enteric bacteria remains an important public health problem in the developing countries. Therefore, this study aimed to determine the prevalence of childhood diarrhea, etiological agents, antibiotic susceptibility patterns and associated risk factors in Eastern Ethiopia.

Subjects and methods

A total of 196 children under the age of 5 years with diarrhea were chosen for the study. Stool specimens were collected for the isolation of bacterial agents and their antibiotic susceptibility pattern using standard methods. Analysis of data was done using SPSS version 16.

Results

The overall prevalence of enteric bacteria observed in this study was 21.9%. The bacterial isolates identified were Escherichia coli (12.8%), Shigella species (5.6%) and Salmonella species (3.6%). Children using an unprotected spring/well source for their water supply were more likely to be infected with diarrhea-causing bacteria (AOR = 4.74, 95% CI: 1.48,15.13). None of the bacterial isolates showed resistance to ceftriaxone, while resistance to amoxicillin was observed for Shigella (100%), Salmonella (85.7%) and E. coli (56%) isolates. Resistance to ampicillin was found to be 90.9%, 71.4% and 52% for Shigella, Salmonella and E. coli isolates. All Shigella isolates were found to be multidrug resistant.

Conclusion

Interventions aimed to improve safe drinking water access should be strengthened/considered in the study area.

Alemu T, Mezgebu Y, Akilew A (2014) Prevalence and determinants of childhood diarrhoea among graduated households, in rural area of Shebedino District, Southern Ethiopia. Sci J Public Health 2(3):243–251CrossRef

Alrifai SB, Alsaadi A, Mahmood YA, Ali AA, Al-Kaisi LA (2009) Prevalence and etiology of nosocomial diarrhoea in children under 5 years in Tikrit Teaching Hospital, Iraq. Eastern Mediterr Health J 15(5):1111–1118

Andualem A (2010) Assessment of the impact of latrine utilization on diarrhoeal diseases in the rural community of Hulet Ejju Enessie Woreda, East Gojjam Zone, Amhara Region. Ethiop J Health Dev 24(3):110–118

Ansari S, Sherchand JB, Parajuli K, Mishra SK, Dahal RK, Shrestha S, Tandukar S, Pokhrel BM (2012) Bacterial etiology of acute diarrhoea in children under five years of age. J Nepal Health Res Counc 10(22):218–223PubMed

Asrat D (2008) Shigella and Salmonella serogroups and their antibiotic susceptibility patterns in Ethiopia. East Mediterr Health J 14:760–767PubMed

Beyene G, Haile-Amlak A (2004) Antimicrobial sensitivity pattern of Campylobacter species among children in Jimma University Specialized Hospital, Southwest Ethiopia. Ethiop J Health Dev 18:185–189

Beyene G, Tasew H (2014) Prevalence of intestinal parasite, Shigella and Salmonella species among diarrhoeal children in Jimma Health Center, Jimma Southwest Ethiopia: A cross-sectional study. Ann Clin Microbiol Antimicrob 13:10. https://doi.org/10.1186/1476-0711-13-10 CrossRefPubMedPubMedCentral

Bhutta ZA, Das JK, Walker N, Rizvi A, Campbell H, Rudan I (2013) Interventions to address deaths from childhood pneumonia and diarrhoea equitably: what works and at what cost? Lancet 381:1417–1429CrossRefPubMed

Cheesebrough M (2006) District laboratory practice in tropical countries. In: Microbiology Part II, 2nd edn. Cambridge University Press, London UK, pp 105–114

CLSI (Clinical Laboratory Standard Institute) (2010) Performance Standard for Antimicrobial Susceptibility Testing; Twentieth Informational Supplement. CLSI document M100- S20. Wayne, PA: Clinical and Laboratory Standards Institute. 30(1): 48-51

CLSI (Clinical Laboratory Standard Institute) (2014) Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Fourth Informational Supplement. CLSI document M100-S24. Wayne, PA: Clinical and Laboratory Standards Institute. 34(1):50-57

CSA (Central Statistics Agency) of Ethiopia (2007). http://www.csa.gov.et/index.php/2013-02-20-14-51-51/2013-04-01.../census-2007

EDHS (Ethiopia Demographic and Health Survey) (2011) Central Statistics Authority and ORC Marco. Ethiopia and Calverton, Maryland, USA, Addis Ababa

El-Astal Z (2005) Bacterial pathogens and their antimicrobial susceptibility in Gaza Strip, Palestine. Pak J Med 20(4):365–370

Elliott EJ (2007) Acute gastroenteritis in children. BMJ 334:35–40CrossRefPubMedPubMedCentral

GBD (Global Burden of Disease), Ethiopia (2010) The Global Burden of Disease, Injuries and Risk Factor Study: Institute for Health Metrics and Evaluation (IHME), University of Washington. Available at http://www.healthmetricsandevaluation.org. Accessed on April 2015

Jeevan BS, Michiyo Y, Ojaswee S, Arun RP, Osamu N (2009) Burden of enteropathogens associated diarrhoeal diseases in Children Hospital, Nepal. Sci World 7(7):71–75. https://doi.org/10.3126/sw.v7i7.3830

Mamo A, Hailu A (2014) Assessment of prevalence and related factors of diarrheal diseases among under-five years children in Debrebirehan Referral Hospital, Debrebirehan Town, North Shoa Zone, Amhara Region, Ethiopia. Open Access Lib J 1:e283

Mengistu G, Mulugeta G, Lema T, Aseffa A (2014) Prevalence and antimicrobial susceptibility patterns of Salmonella serovars and Shigella species. J Microb Biochem Technol S2:006. https://doi.org/10.4172/1948-5948.S2-006

Mitikie G, Kassu A, Genetu A, Nigussie D (2000) Campylobacter enteritis among children in Dembia District. Northwest Ethiopia East Afr Med J 77(654-6):57

Mulatu G, Beyene G, Zeynudin A (2014) Prevalence of Shigella, Salmonella and Campylobacter Species and their susceptibility pattern among under five children with diarrhoea in Hawassa Town, South Ethiopia. Ethiop J Health Sci 24(2):101–107CrossRefPubMedPubMedCentral

Naghipour M, Nakgomi T, Nakagomi O (2008) Issues with reducing the rotavirus associated mortality by vaccination in developing countries. Vaccine 26:3236–3241CrossRefPubMed

Pokharela BM, Janak K, Rajan KD, Shyam KM, Prem KK, Tuladhara NR (2006) Multidrug-resistant and extended-spectrum beta-lactamase (ESBL)-producing Salmonella enterica (serotypes Typhi and Paratyphi A) from blood isolates in Nepal: surveillance of resistance and a search for newer alternatives. Intl J Infect Dis 10(6):434–438CrossRef

Randrianirina F, Elisoa HR, Lova R, Rindra R, Hanitra CR, Tahiry A, Fanjasoa R, Soatiana R, Vincent R, Antoine T (2014) Antimicrobial resistance of bacterial enteropathogens isolated from stools in Madagascar. BMC Infect Dis 14:104. https://doi.org/10.1186/1471-2334-14-104

Ravi S, Singh SP, Tripathi CB (2004) Persistent diarrhoea: approaches for the management among under five children. Ind J Pre Soc Med 35(3):115–119

Reda A, Seyoum B, Jemal Y, Andualem G, Fiseha S, Jean-Michel V (2011) Antibiotic susceptibility patterns of Salmonella and Shigella isolates in Harar, Eastern Ethiopia. J Infect Dis Immunol 3:134–139

Roma B, Worku S, Mariam ST, Langeland N (2000) Antimicrobial susceptibility pattern of Shigella isolates in Hawassa. Ethiop J Health Dev 14:149–154CrossRef

Senthilkumar B, Prabakaran G (2005) Multidrug resistant Salmonella typhi in asymptomatic typhoid carriers among food handlers in Namakkal District Tamil Nadu. Ind J Med Microbiol 23(2):92–94CrossRef

Senthilkumar B, Senbagam D, Rajasekarapandian M (2014a) An epidemiological surveillance of asymptomatic typhoid carriers associated in respect to socioeconomic status in India. J Public Health 22:297–301CrossRef

Senthilkumar B, Zothansanga, Senbagam D, Senthilkumar N, Gurusubramaniam G (2014b) Practical Microbiology-A Laboratory Manual. Panima Publishing Corp., New Delhi, India. https://doi.org/10.13140/2.1.2667.6163

Senthilkumar B, Ilakkia S, Selvam K, Senbagam D, Nachimuthu S, Guruswami G (2017) Biosynthesis of silver nanoparticles using Myristica fragrans seeds (nutmeg) extract and its antibacterial activity against multidrug resistant (MDR) Salmonella enteric serovar Typhi isolates. Environ Sci Pollut Res. https://doi.org/10.1007/s11356-017-9065-7

Temu MM, Kaatano GM, Miyaye ND, Buhalata SN, Shushu M-L, Kishamawe C, Changalucha JM (2007) Antimicrobial susceptibility of S. flexneri and S. dysenteriae isolated from stool specimens of patients with bloody diarrhoea in Mwanza, Tanzania. Tanza Health Res Bull 9:186–189

UNICEF (UN Inter-Agency Group for Child Mortality Estimation) (2012) Levels and Trends in Child Mortality. United Nations International Children’s Emergency Fund, New York Available at http://www.apromiserenewed.org/wp-content/uploads/2015/03/UNICEF_2012_child_mortality_for_web_0904

UNICEF/WHO (2009) Diarrhoea: Why Children Are Still Dying and What Can Be Done. Available at http://apps.who.int/iris/bitstream/10665/44174/1/9789241598415_eng

Urio EM, Collison EK, Gashe BA, Sebunya TK, Mpuchane S (2001) Shigella and Salmonella strains isolated from children under 5 years in Gaborone, Botswana, and their antibiotic susceptibility patterns. Trop Med Int Health 6(1):55–59CrossRefPubMed

Wanzahun G, Bezatu M (2013) Environmental factors associated with acute diarrhea among children under five years of age in Derashe District, Southern Ethiopia. Sci J Public Health 1(3):119–124CrossRef

Willie KS, Valerie O, David S (2012) Prevalence and antibiotic resistance of bacterial pathogens isolated from childhood diarrhea in four provinces of Kenya. J Infect Dev Countries 6(7):572–578

Wondwossen BE (2008) A stepwise regression analysis on under-five diarrhoeal morbidity prevalence in Nekemte town, western Ethiopia: maternal care giving and hygiene behavioral determinants. East Afr J Public Health 5(3):193–198

World Gastroenterology Organization (2008) practice guideline: Acute diarrhea. Available at http://www.ngc.org

Yismaw G, Negeri C, Kassu A (2006) A five-year antimicrobial resistance pattern observed in Shigella species isolated from stool samples in Gondar University Hospital, Northwest Ethiopia. Ethiop J Health Dev 20(3):194–198

Titel: Prevalence of childhood diarrhea and associated risk factors in Dire Dawa, eastern Ethiopia
verfasst von: Mohammed Mekonnen
Biftu Geda
Zelalem Teklemariam
Fitsum Weldegebreal
Senthilkumar Balakrishnan
Publikationsdatum: 01.10.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: Journal of Public Health / Ausgabe 1/2018
Print ISSN: 2198-1833
Elektronische ISSN: 1613-2238
DOI: https://doi.org/10.1007/s10389-017-0843-y

Springer Medizin

Abstract

Aim

Subjects and methods

Results

Conclusion

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